ANTI-MRSA

作品数：8被引量：6H指数：2
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相关期刊：《Chinese Journal of Natural Medicines》《Journal of Pharmacy and Pharmacology》《Journal of Pharmaceutical Analysis》《Research in Cold and Arid Regions》更多>>
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Quinosumycin,a novel anti-MRSA thioether-linked quinolinone-quinazolinone heterodimer from a marine actinomycete Streptomyces diastaticus NBU2966
《Journal of Oceanology and Limnology》2024年第6期1991-1997,共7页Shuangling TAN Yang LIU Haonan FU Yutong XUE Fangjian FENG Jinling LI Xiaojun YAN Sitong WU Shan HE Lijian DING 
Supported by the National Natural Science Foundation of China(No.42176101);the Ningbo Youth Science and Technology Innovation Leading Project(No.2024QL063);the National 111 Project of China(No.D16013);the Scientific Research Fund of Zhejiang Provincial Education Department(No.Y202250186);the Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Development Fund。
Marine natural products offer a promising source in the development of new antibiotic drugs.Two previously undescribed compounds,including one sulfur-bearing alkaloid named quinosumycin(1)along with one chromone deriv...
关键词：marine natural product marine Streptomyces THIOETHER alkaloid HETERODIMER anti-methicillinresistant Staphylococcus aureus(anti-MRSA) 
New nor-ent-halimane and nor-clerodane diterpenes from Callicarpa integerrima with anti-MRSA activity
《Chinese Journal of Natural Medicines》2024年第11期1003-1010,共8页WANG Mengru WANG Qi MA Yanzi ZEB Muhammad Aurang LI Xiaoli SHEN Feng XIAO Weilie 
supported by the National Natural Science Foundation of China(Nos.22477108,82260682);the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT_17R94);the Project of Yunnan Characteristic Plant Screening and R&D Service CXO Platform(No.2022YKZY001);the Scientific Research Fund of Yunnan Provincial Department ofEducation(No.2023Y0235)。
Two new nor-ent-halimane diterpenes and three previously unreported nor-clerodane diterpenes,designated callicain-tides A-E(1-5),were isolated from Callicarpa integerrima.Compounds 1 and 2 feature a distinctive 5/6-me...
关键词：Callicarpa integerrima Halimane diterpenes Clerodane diterpenes Structure elucidationanti-MRSA 
Discovery of potent anti-MRSA components from Dalbergia odorifera through UPLC-Q-TOF-MS and targeting PBP2a protein through in-depth transcriptomic,in vitro,and in-silico studies
《Journal of Pharmaceutical Analysis》2024年第8期1251-1254,共4页Jiajia Wu Syed Shams ul Hassan Xue Zhang Tao Li Abdur Rehman Shikai Yan Huizi Jin 
the National Natural Science Foundation of China(Grant No.:81973191);Shanghai Agriculture Applied Technology Development Program,China(Program No.:T20200104);the National Key Research and Development Program of China(Program No.:2018YFE0192600)for providing financial support for the complete undertaking.
Methicillin-resistant Staphylococcus aureus(MRSA)is an important pathogen casting dire shadow over global human wellbeing[1].Rising antibiotic resistance in MRSA led to research into plant-derived anti-microbial agent...
关键词：protective MRSA anti 
Quinoline-based anti-MRSA agents: Current development, structure-activity relationships, and mechanisms
《Chinese Chemical Letters》2024年第1期52-63,共12页Hong Yao Liping Cui Hang Liu Xueyu Li Lin Shen Ruige Yang Shangshang Qin Yong Guo 
the National Natural Science Foundation of China(No.32272575);National College Student Innovation and Entrepreneurship Training Program(No.202210459164)for financial support.
Methicillin-resistant Staphylococcus aureus (MRSA), the most common pathogen in hospital and community environments, can cause serious and even fatal infections. The antibiotics currently used for clinical treatment o...
关键词：Quinoline analogue Methicillin-resistant Staphylococcus aureus Antibacterial activity Structure–activity relationship Antibacterial mechanism 
Mode of Action and Cytotoxicity of Bioactive Compounds Produced by Streptomyces sp. KB1
《Journal of Pharmacy and Pharmacology》2019年第9期499-503,共5页Monthon Lertcanawanichakul Kittisak Chawawisit 
Rapid emergence of methicillin-resistant Staphylococcus aureus (MRSA) has led to search of a novel bioactive compounds from natural resources. This study was aimed to determine the mode of action of bioactive compound...
关键词：ANTI-MRSA activity  bioactive compounds  MODE of action  cytotoxicity  STREPTOMYCES sp. KB1 TISTR 2304 
Nocardiopsistins A-C:New angucyclines with anti-MRSA activity isolated from a marine sponge-derived Nocardiopsis sp.HB-J378被引量：3
《Synthetic and Systems Biotechnology》2018年第4期246-251,共6页Dongbo Xu Keshav K.Nepal Jing Chen Dedra Harmody Haining Zhu Peter J.McCarthy Amy E.Wright Guojun Wang 
This work was supported in part by the NIH grant CA209189.
Marine natural products have become an increasingly important source of new drug leads during recent years.In an attempt to identify novel anti-microbial natural products by bioprospecting deep-sea Actinobacteria,thre...
关键词：NOCARDIOPSIS Nocardiopsistins Angucycline ANTI-MRSA ACTINOBACTERIA LaCl_(3) 
High-quality draft genome sequence of Streptomyces agglomeratus 5-1-8 with strong anti-MRSA ability, isolated from the frozen soil of Tibet in China
《Research in Cold and Arid Regions》2017年第5期503-510,共8页XiMing Chen Ling Zhang HaiLi Sun ShuYan Li SiJing Chang QingFeng Zhang BingLin Zhang Tuo Chen GuangXiu Liu Paul Dyson 
supported by the National Natural Science Foundation of China (Grant No. 31400437);the international cooperation program of Gansu (1504WKCA097);the application transformationfoundation of CAS (HHS-CGZH-16-02);UK BBSRC China Partnering Grant (BB/J020419/1)
Streptomyces agglomeratus 5-1-8 with strong anti methicillin-resistant Staphylococcus aureus(MRSA)ability,isolated from the frozen soil of Tibet in China,has a strong ability to kill the multi-drugs-resistant MRSA.To ...
关键词：STREPTOMYCES antibiotic multi-drugs-resistant MRSA genome gene cluster 
Anti-methicillin-resistant Staphylococcus aureus assay of azalomycin F_(5a) and its derivatives被引量：3
《Chinese Journal of Natural Medicines》2014年第4期309-313,共5页YUAN Gan-Jun LI Pei-Bo YANG Jun PANG Hui-Zhong PEI Ying 
supported by the Jiangxi Province Science and Technology Supporting Plan(No.20111BBG7006-1);the National Natural Science Foundation of China(No.81260476)
AIM: To discover anti-methicillin-resistant Staphylococcus aureus(anti-MRSA) microbial natural products or their derivatives. METHOD: Azalomycin F5a(1) was prepared through fermentation of Streptomyces hygroscopicus v...
关键词：Azalomycin F5a ANTI-MRSA Demalonyl Derivatives Macrocyclic antibiotics 
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