support from the Helmholtz International Lab(InterLabs0007);Yuhao Ren acknowledges the support from the International Postdoctoral Exchange Fellowship Program(ZD202125)between Helmholtz Association;Germany and the Office of China Postdoc Council(OCPC),China.
The biosynthetic potential of actinobacteria to produce novel natural products is still regarded as immense.In this paper,we correlated a cryptic biosynthetic gene cluster to chemical molecules by genome mining and ch...
the Guangdong Basic and Applied Basic Research Foundation(2021A1515011523,2021B1515120046,2022B1515120075);National Key Research and Development Program of China(2022YFC2807501);National Natural Science Foundation of China(grant no.41976224);Hainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City(2021JJLH0097,2021CXLH0013);Hainan Provincial Natural Science Foundation of China(823CXTD393)。
Microbes well-adapted to the Arctic Ocean are promising for producing novel compounds,due to their fancy strategies for adaptation and being under-investigated.Two new phenazine alkaloids(1 and 2)and one new phenoxa-z...
This work was supported in part by the NIH grant CA209189.
Marine natural products have become an increasingly important source of new drug leads during recent years.In an attempt to identify novel anti-microbial natural products by bioprospecting deep-sea Actinobacteria,thre...