supported by the ARC Industrial Transformation Training Centre for Multiscale 3D Imaging,Modelling,and Manufacturing[IC 180100008],NHMRC 2008018-Transformation of the implant paradigm in breast rehabilitation Grant;the Max Planck Queensland Centre.
Biofilm-related biomaterial infections are notoriously challenging to treat and can lead to chronic infection and persisting inflammation.To date,a large body of research can be reviewed for coatings which potentially...
supported by the following NIH grants:R01 grants(AR075860,AR077616,and AR083900 to JS;HL138175,HL164062,and DK133949 to JG)and a R21 grant(AR077226 to JS);a P30 Core Center grant(AR074992 to the Musculoskeletal Research Center at Washington University in St.Louis).
Critical size bone defects represent a significant challenge worldwide,often leading to persistent pain and physical disability that profoundly impact patients’quality of life and mental well-being.To address the int...
The authors regret.The cytoskeleton staining images in Fig.5(C)of the original manuscript overlap,as shown in the white dotted box below.Given this error,we re-supplement the relevant experime...
supported by the National Natural Science Foundation of China(52071277,21802009);Jiangsu Provincial Key Research and Development Program(CN)(BE2019608);China Postdoctoral Science Foundation(2022M721685);Jiangsu Health Commission Medical Research Program(2020158);National Facility for Translational Med-icine(Shanghai)Open Program(TMSK-2021-304);2020 Nanjing In-ternational Science and Technology Cooperation Program;Nanjing Medical Science and Technology Development Key Program(ZKX18041).
The resection of malignant osteosarcoma often results in large segmental bone defects,and the residual cells can facilitate recurrence.Consequently,the treatment of osteosarcoma is a major challenge in clinical practi...
The authors regret.The cytoskeleton staining images in Fig.5(C)of the original manu-script overlap,as shown in the white dotted box below.Given this error,we re-supplement the relevant experim...
supported by the National Natural Science Foundation of China(32071359,11827803,61227902,and U20A20390);National Key Technology R&D Program(2020YFC0122203);International Joint Research Center of Aerospace Biotechnology and Medical Engineering from Ministry of Science and Technology of China;111 Project(B13003);Research Fund for the Doctoral Program of Higher Education of China(20131102130004);Fundamental Research Funds for the Central Universities.
Cell sheet engineering has been proven to be a promising strategy for cardiac remodeling post-myocardial infarction. However, insufficient mechanical strength and low cell retention lead to limited therapeutic efficie...
National Key Research and Development Program of China(grant number 2017YFC1104900);National Natural Science Foundation of China(No.51871239,51771227,52171244 and 81772328);The authors also appreciate the support from the Incubation Project of the Army’s Medical Technology Youth Cultivation Program of China(17QNP021)。
Biodegradable polycaprolactone/β-tricalcium phosphate(PT)composites are desirable candidates for bone tissue engineering applications.A higherβ-tricalcium phosphate(TCP)ceramic content improves the mechanical,hydrop...
supported by grants from Zhejiang Provincial Natural Science Foundation of China(LR19H160002);National Natural Science Foundation of China(82073296 and 81773193);Research Project of Jinan Microecological Biomedicine Shandong Laboratory(JNL-2022010B).
The recent remarkable success and safety of mRNA lipid nanoparticle technology for producing severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vaccines has stimulated intensive efforts to expand nanoparticle ...
This study is supported by NIH Grants 1R01DE029321 to C.H.L.
The inevitable gap between in vitro and in vivo degradation rate of biomaterials has been a challenging factor in the optimal designing of scaffold’s degradation to be balanced with new tissue formation.To enable non...
This study was supported by the Innovation research program[HHKT-00-03];the National Natural Science Foundation of China[grant numbers 82170929,81970908,51901003,81200814,and 81771039].
Guided bone regeneration membranes have been effectively applied in oral implantology to repair bone defects.However,typical resorbable membranes composed of collagen(Col)have insufficient mechanical properties and hi...