OSTEOGENIC

作品数：144被引量：451H指数：9
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相关领域：医药卫生生物学更多>>
相关作者：鄂玲玲张硕刘洪臣游利陈瑾瑜更多>>
相关机构：中国人民解放军总医院南京医科大学第二军医大学第四军医大学更多>>
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Runx2 controls the osteogenic fate of growth plate chondrocytes
《Genes & Diseases》2025年第3期1-3,共3页Daofu Zeng Jiamin Yu Ke Lu Dan Yi Zhidao Xia Ling Qin Guozhi Xiao Xiao Yang Liping Tong Di Chen 
supported by the National Key Research and Development Program of China(No.2022YFA1207500);the National Natural Science Foundation of China(No.82394445 to D.C.and L.T.;82250710174 and 82030067 to D.C.;82161160342 to D.C.and L.Q.);the Shenzhen Science and Technology Research Funding(No.JCYJ20220818101414032 to L.T.;JSGGKQTD20210831174330015 to D.C.).
The origin of bone marrow osteoblasts is not totally understood.Recent findings demonstrated that bone marrow osteoblasts could be derived from a subpopulation of hypertrophic Col2^(+)/Col10^(+)chondrocytes which migr...
关键词：RUNX mesenchymal progenitor cells chondrocyte osteoblast transdifferentiation hypertrophic chondrocytes growth plate bone marrow bone marrow osteoblasts 
Biomaterials science and surface engineering strategies for dental peri‑implantitis management
《Military Medical Research》2025年第3期354-392,共39页Ya-Meng Yu Yu-Pu Lu Ting Zhang Yu-Feng Zheng Yun-Song Liu Dan-Dan Xia 
supported by the National Key Research and Development Program of China(2023YFC2412600);the National Natural Science Foundation of China(52271243,52171233,82370924,82170929);the Beijing Natural Science Foundation(L212014);the Beijing Nova Program(20230484459);the National Clinical Key Discipline Construction Project(PKUSSNKP-T202103);the Research Foundation of Peking University School and Hospital of Stomatology(PKSS20230104).
Peri-implantitis is a bacterial infection that causes soft tissue inflammatory lesions and alveolar bone resorption,ultimately resulting in implant failure.Dental implants for clinical use barely have antibacterial pr...
关键词：PERI-IMPLANTITIS Dental implant Osteogenic property Antibacterial activity Anaerobic bacteria 
EZH2,via an association with KDM2B,modulates osteogenic differentiation of root apical papillary stem cells
《World Journal of Stem Cells》2025年第4期99-112,共14页Hui-Yue Xu Yan-Tong Wang Hao-Qing Yang Yang-Yang Cao Zhi-Peng Fan 
Supported by National Key Research and Development Program,No.2022YFA1104401;Beijing Natural Science Foundation,No.7222075;CAMS Innovation Fund for Medical Sciences,No.2019RU020;Innovation Research Team Project of Beijing Stomatological Hospital,No.CXTD202204.
BACKGROUND Stem cells from apical papilla(SCAPs)represent promising candidates for bone regenerative therapies due to their osteogenic potential.However,enhancing their differentiation capacity remains a critical chal...
关键词：Bioactive peptides Bone tissue engineering Enhancer of zeste homolog 2 OSTEOGENIC Apical papillary stem cell 
Enhanced wear resistance,antibacterial performance,and biocompatibility using nanotubes containing nano-Ag and bioceramics in vitro
《Bio-Design and Manufacturing》2024年第5期670-686,共17页Qingge Wang Jia Liu Hong Wu Jingbo Liu Yaojia Ren Luxin Liang Xinxin Yan Ian Baker Shifeng Liu V.V.Uglov Chengliang Yang Liqiang Wang 
supported by the National Natural Science Foundation of China(Nos.52071346,52111530193,and 52274387);the Natural Science Foundation of Hunan Province for Distinguished Young Scholars(No.2023JJ10075);the Hunan Provincial Natural Science Foundation of China(No.2021JJ30846);the Central South University Research Program of Advanced Interdisciplinary Studies(No.2023QYJC038);the Funding for the Medical Engineering Cross Disciplinary Project at Shanghai Jiao Tong University,and the Fundamental Research Funds for the Central Universities of Central South University(No.2022ZZTS0402);The authors would also thank Sinoma Institute of Materials Research(Guangzhou)Co.,Ltd.for the assistance with the TEM characterization.
A good Ti-based joint implant should prevent stress shielding and achieve good bioactivity and anti-infection performance.To meet these requirements,the low-elastic-modulus alloy—Ti–35Nb–2Ta–3Zr—was used as the s...
关键词：βTi alloy Surface modification Wear resistance Corrosion resistance Osteogenic behavior Antibacterial activity 
Porous Ti_(3)SiC_(2)ceramics with improved osteogenic functions via biomineralization as load-bearing bone implants
《Journal of Materials Science & Technology》2024年第28期248-259,共12页Qian Xu Shuze Wang Yun Bai Qiang Wang Rui Yang Xiaohui Wang Xiaowu Li Xing Zhang 
supported by the National Natural Science Foundation of China(No.52273278);the Liaoning Revitalization Talents Program(No.XLYC2007112).
Ti_(3)SiC_(2)ceramics exhibit excellent mechanical properties and good biocompatibility,rendering them promising bone substitutes for load-bearing conditions.However,the bone integration and osteogenic ability of Ti_(...
关键词：Ti_(3)SiC_(2)scaffolds BIOMINERALIZATION Macrophage polarization Bone regeneration 
Solitary Osteogenic Exostosis of the Femur Revealed by Recurring Acute Distal Thigh Pain: About a Case
《Open Journal of Pediatrics》2024年第4期719-726,共8页Thierno Saïdou Barry Mohamed Lamine Sadou Sacko Balla Keita Sory Sidimé Moussa Condé Daniel Agbo-Panzo 
Introduction: Solitary exostoses are the most common benign tumors of the fertile metaphyses of the long bones of children. Their radiological diagnosis of metaphyseal bone growth must be confirmed on pathological exa...
关键词：Osteogenic Exostosis Osteochondromas Fertile Long Bone Metaphyses Child 
Enhancing osteogenic bioactivities of coaxial electrospinning nanoscaffolds through incorporating iron oxide nanoparticles and icaritin for bone regeneration
《Nano Research》2024年第7期6430-6442,共13页Peng Wang Qianjin Wang Dengxian Wu Yunyang Zhang Shixiong Kang Xucai Wang Jiayu Gu Hao Wu Zhihong Xu Qing Jiang 
supported by the National Basic Research Program of China(Nos.2021YFA1201404,and 2019YFA0210103);the National Natural Science Foundation of China(Nos.32271413,and 82272492);Natural Science Foundation of Jiangsu Province(No.BK20232023);Science program of Jiangsu Province Administration for Market Regulation(No.KJ2024010).
Bone tissue engineering provides a promising strategy for the treatment of bone defects.Nonetheless,the clinical utilization of biomaterial-based scaffolds is constrained by their inadequate mechanical strength and ab...
关键词：iron oxide nanoparticles ICARITIN coaxial electrospinning nano-scaffolds MEK/ERK signaling pathway bone regeneration 
持续释放蒙脱土插层杂化复合材料中的成骨微量元素促进骨再生
《Science China Materials》2024年第7期2067-2079,共13页童磊 刘泉滢 熊丽 王培磊 赵明达 李星 梁洁 樊渝江 张兴栋 孙勇 
sponsored by National Natural Science Foundation of China(32271419,32071352)。
优化支架组分和结构以实现内源性成骨是骨组织工程中一项有前景的进展.本研究将蒙脱土作为一种增强相,以插层结构引入到多巴胺介导的仿生有机/无机杂化水凝胶中.通过蒙脱土-聚合物相互作用和多酚介导的多重反应改善了骨再生支架(HDC-HAp...
关键词：MONTMORILLONITE osteogenic elements hybrid com-posites bone regeneration 
The marriage of immunomodulatory,angiogenic,and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scafold for military medicine
《Military Medical Research》2024年第3期323-344,共22页Ping Wu Lin Shen Hui-Fan Liu Xiang-Hui Zou Juan Zhao Yu Huang Yu-Fan Zhu Zhao-Yu Li Chao Xu Li-Hua Luo Zhi-Qiang Luo Min-Hao Wu Lin Cai Xiao-Kun Li Zhou-Guang Wang 
supported by the National Natural Science Foundation of China(82202352,82271629);the Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University(ZNLH202202);the China Postdoctoral Science Foundation Funded Project(2023M732711);the Wenzhou Medical University grant(QTJ23004)。
Background:Most bone-related injuries to grassroots troops are caused by training or accidental injuries.To establish preventive measures to reduce all kinds of trauma and improve the combat effectiveness of grassroot...
关键词：Piezoelectric hydrogel Tissue engineering scafold IMMUNOMODULATION Angiogenesis Osteogenic differentiation 
Sustained adenosine release:Revealing its impact on osteogenic signalling pathways of human mesenchymal stromal cells
《Engineered Regeneration》2024年第2期255-268,共14页Hadi Hajiali Jane McLaren Cristina Gonzalez-García Salah Abdelrazig Dong-Hyun Kim Matthew J.Dalby Manuel Salmerón-Sánchez Felicity R.A.J.Rose 
Financial support was received from Engineering and Physical Sci-ences Research Council(EPSRC);Reference:EP/P001114/;Engineering growth factor microenvironments-a new therapeutic paradigm for re-generative medicine.
Non-healing fractures,a global health concern arising from trauma,osteoporosis,and tumours,can lead to severe disabilities.Adenosine,integral to cellular energy metabolism,gains prominence in bone regeneration via ade...
关键词：Adenosine release Osteogenic signalling pathways Human mesenchymal stromal cells Bone regeneration 
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