ADDICTION

作品数:228被引量:201H指数:7
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相关领域:医药卫生更多>>
相关作者:胡莹赵艳刘贤宇王秋海张娟更多>>
相关机构:宁波大学宁波市第一医院睢宁县凌城中学河北昌黎第一中学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家科技支撑计划更多>>
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N-acetylaspartylglutamate Inhibits Heroin Self-Administration and Heroin-Seeking Behaviors Induced by Cue or Priming in Rats被引量:1
《Neuroscience Bulletin》2017年第4期396-404,共9页Huaqiang Zhu Miaojun Lai Weisheng Chen Disen Mei Fuqiang Zhang Huifeng Liu Wenhua Zhou 
supported by the National Basic Research Program of China(2015CB553504);the National Natural Science Foundation of China(81471350 and 81671321);the Natural Science Foundation of Ningbo Municipality,Zhejiang Province,China(2015A610193)
Activation of presynaptic group II metabotropic glutamate receptors(mGluR2/3) inhibits drug reward and drug-seeking behavior, but the role of N-acetylaspartylglutamate(NAAG), an agonist of endogenous mGluR2/3,in h...
关键词:Glutamate OPIOID Metabotropic glutamate receptor Reward ADDICTION 
Disruption of dopamine D1 receptor phosphorylation at serine 421 attenuates cocaine-induced behaviors in mice被引量:1
《Neuroscience Bulletin》2014年第6期1025-1035,共11页Ying Zhang Ning Wang Ping Su Jie Lu Yun Wang 
supported by grants from the National Natural Science Foundation of China (91332119,81161120497,30925015,30830044,31371143,30900582 and 81221002);the National Basic Research Development Program from the Ministry of Science and Technology of China (2014CB542204)
Dopamine D1 receptors(D1Rs) play a key role in cocaine addiction, and multiple protein kinases such as GRKs, PKA, and PKC are involved in their phosphorylation. Recently, we reported that protein kinase D1 phosphory...
关键词:protein kinase D1 dopamine D1 receptor PHOSPHORYLATION COCAINE ADDICTION conditioned place preference locomotor activity 
Decreased frontal lobe function in people with Internet addiction disorder
《Neural Regeneration Research》2013年第34期3225-3232,共8页Jun Liu Fatema Esmail Lingjiang Li Zhifeng Kou Weihui Li Xueping Gao Zhiyuan Wang Changlian Tan Yan Zhang Shunke Zhou 
supported by the National Natural Science Foundation of China,No.30830046,30670751,30570695;the National Science and Technology Program of China,No.2007BAI17B02;the National 973 Program of China,No.2009CB918303;the Natural Science Foundation of Hunan Province of China,No.07JJ3042;Department of Public Health of Hunan Province of China,No.B2005048
In our previous studies, we showed that frontal lobe and brainstem functions were abnormal in online game addicts. In this study, 14 students with Internet addiction disorder and 14 matched healthy controls underwent ...
关键词:neural regeneration Internet addiction disorder internet gaming addiction magnetic resonanceimaging magnetic resonance spectroscopy N-ACETYLASPARTATE choline-containing compounds CREATINE grants-supported paper NEUROREGENERATION 
The role of K-opioid receptor activation in mediating antinociception and addiction被引量:8
《Acta Pharmacologica Sinica》2010年第9期1065-1070,共6页Yu-hua WANG Jian-feng SUN Yi-min TAO Zhi-qiang CHI Jing-gen LIU 
The K-opioid receptor (KOR), a member of the opioid receptor family, is widely expressed in the central nervous system and peripheral tissues. Substantial evidence has shown that activation of KOR by agonists and en...
关键词:K-opioid receptor DYNORPHIN DESENSITIZATION ANTINOCICEPTION tolerance ADDICTION drug withdrawal cocaine reward nega-tive mood state 
Chronic morphine drinking establishes morphine tolerance, but not addiction in Wistar rats被引量:3
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2006年第11期892-898,共7页BINSACK Ralf ZHENG Ming-lan ZHANG Zhan-sai YANG Liu ZHU Yong-ping 
Project supported by the National Basic Research Program (973) of China (No. 2003CB515402), and the Science and Technology Council of Zhejiang Province (No. 2005C23G2010166), China
Objective: Some animal models apply morphine in the drinking water to generate addiction, but related reports are not free of conflicting results. Accordingly, this study aimed to figure out if chronic consumption of...
关键词:ADDICTION MORPHINE SELF-ADMINISTRATION TOLERANCE Wistar rats 
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