ADDICTION

作品数：228被引量：201H指数：7
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Orexin Receptor Antagonists as Emerging Treatments for Psychiatric Disorders被引量：19
《Neuroscience Bulletin》2020年第4期432-448,共17页Ying Han Kai Yuan Yongbo Zheng Lin Lu 
the National Natural Science Foundation of China(81701312 and 81521063);the Interdisciplinary Medicine Seed Fund of Peking University(BMU2018MX024).
Orexins comprise two neuropeptides produced by orexin neurons in the lateral hypothalamus and are released by extensive projections of these neurons throughout the central nervous system. Orexins bind and activate the...
关键词：OREXIN INSOMNIA DEPRESSION ANXIETY Drug ADDICTION 
MicroRNA-132 in the Adult Dentate Gyrus is Involved in Opioid Addiction Via Modifying the Differentiation of Neural Stem Cells被引量：6
《Neuroscience Bulletin》2019年第3期486-496,共11页Meng Jia Xuewei Wang Haolin Zhang Can Ye Hui Ma Mingda Yang Yijing Li Cailian Cui 
supported by grants from the National Natural Science Foundation(81471353 and 81771433);the National Basic Research Development Program of China(2015CB553500);the Science Fund for Creative Research Groups from the National Natural Science Foundation of China(81521063)
MicroRNA-132(miR-132), a small RNA that regulates gene expression, is known to promote neurogenesis in the embryonic nervous system and adult brain.Although exposure to psychoactive substances can increase miR-132 exp...
关键词：miR-132 OPIOID ADDICTION Neural stem cell DENTATE GYRUS 
N-acetylaspartylglutamate Inhibits Heroin Self-Administration and Heroin-Seeking Behaviors Induced by Cue or Priming in Rats被引量：1
《Neuroscience Bulletin》2017年第4期396-404,共9页Huaqiang Zhu Miaojun Lai Weisheng Chen Disen Mei Fuqiang Zhang Huifeng Liu Wenhua Zhou 
supported by the National Basic Research Program of China(2015CB553504);the National Natural Science Foundation of China(81471350 and 81671321);the Natural Science Foundation of Ningbo Municipality,Zhejiang Province,China(2015A610193)
Activation of presynaptic group II metabotropic glutamate receptors（mGluR2/3） inhibits drug reward and drug-seeking behavior, but the role of N-acetylaspartylglutamate（NAAG）, an agonist of endogenous mGluR2/3,in h...
关键词：Glutamate OPIOID Metabotropic glutamate receptor Reward ADDICTION 
Calcium-Impermeable NMDA Receptor:A Novel Target for Addiction被引量：2
《Neuroscience Bulletin》2017年第3期357-358,共2页Xiaodan Huang Wei Ni Changzheng Zhang 
supported by grants from the Postdoctoral Foundation of Jiangsu Province,China(1601180B);a Project of the Postdoctoral Science Foundation of China(2016M601841)
Drug addiction results in long-term synaptic potentiation at excitatory synapses in the brain reward circuitry,especially in the ventral tegmental area（VTA）and nucleus accumbens（NAc）,central parts of the mesolimbi...
关键词：potentiation excitatory dopamine addiction synaptic cortical NMDA ventral Receptor nucleus 
Special Topic on Mental Health and Addiction
《Neuroscience Bulletin》2016年第6期509-511,共3页Lin Lu Wenhua Zhou 
We are delighted to have been invited to edit this Special Topic on Mental Health and Addiction. Mental disorders like drug addiction, mood disorders, and schizophrenia affect a sizeable proportion of the human popula...
关键词：Special Topic on Mental Health and Addiction GENE VNTR 
Non-invasive Brain Stimulation for the Treatment of Nicotine Addiction:Potential and Challenges被引量：3
《Neuroscience Bulletin》2016年第6期550-556,共7页Li-Zhuang Yang Zhiyu Yang Xiaochu Zhang 
supported by grants from the National Natural Science Foundation of China(31471071 and 31500917);China Postdoctoral Science Foundation(2016M592051);Fundamental Research Funds for the Central Universities of China (WK2070000033);Hefei Science Center,CAS "User with Potential",China(2015HSC-UP017)
Abstract Tobacco consumption is one of the leading causes of preventable death worldwide. However, it is difficult to give up smoking by relying on the help of tra- ditional treatments only. Recent years have witnesse...
关键词：TMS TDCS NIBS NICOTINE ADDICTION 
Disruption of dopamine D1 receptor phosphorylation at serine 421 attenuates cocaine-induced behaviors in mice被引量：1
《Neuroscience Bulletin》2014年第6期1025-1035,共11页Ying Zhang Ning Wang Ping Su Jie Lu Yun Wang 
supported by grants from the National Natural Science Foundation of China (91332119,81161120497,30925015,30830044,31371143,30900582 and 81221002);the National Basic Research Development Program from the Ministry of Science and Technology of China (2014CB542204)
Dopamine D1 receptors（D1Rs） play a key role in cocaine addiction, and multiple protein kinases such as GRKs, PKA, and PKC are involved in their phosphorylation. Recently, we reported that protein kinase D1 phosphory...
关键词：protein kinase D1 dopamine D1 receptor PHOSPHORYLATION COCAINE ADDICTION conditioned place preference locomotor activity 
Regulation of dopamine D3 receptors by protein-protein interactions
《Neuroscience Bulletin》2010年第2期163-167,共5页郭鸣雷 刘贤宇 毛利民 王强 
supported by the grant from the Saint Luke’s Hospital Foundation (Kansas City, MO, USA);grants (No. R01-DA010355, R01-MH061469) from the National Institutes of Health (Bethesda,MD, USA)
Gαi/o protein-coupled dopamine D3 receptors （D3Rs） are preferentially expressed in the limbic system, including the nucleus accumbens. This situates the receptor well in the regulation of limbic function and in the...
关键词：STRIATUM CAUDATE phosphorylation COCAINE ADDICTION cAMP CAMKII 
Repeated morphine treatment influences operant and spatial learning differentially被引量：4
《Neuroscience Bulletin》2006年第3期137-143,共7页Mei-Na WANG Zhi-Fang DONG Jun CAO Lin XU 
This work was supported by grants from the National Natural Science Foundation of China （No. 30470549）;the National Basic Research Priorities Programme （973） of China （No.2006CBS00800）
Objective To investigate whether repeated morphine exposure or prolonged withdrawal could influence operant and spatial learning differentially. Methods Animals were chronically treated with morphine or subjected to m...
关键词：MORPHINE ADDICTION WITHDRAWAL CONDITIONING spatial learning 
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