CONVERTASE

作品数:6被引量:7H指数:2
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相关领域:医药卫生更多>>
相关作者:孙静许正宏更多>>
相关机构:中国医学科学院江南大学中南大学中南大学湘雅二医院更多>>
相关期刊:《Neural Regeneration Research》《Journal of Hainan Medical University》《中国心血管病研究》《Journal of Cancer Therapy》更多>>
相关基金:国家自然科学基金国家教育部博士点基金更多>>
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Proprotein convertase 1/3-mediated down-regulation of brain-derived neurotrophic factor in cortical neurons induced by oxygen-glucose deprivation被引量:3
《Neural Regeneration Research》2020年第6期1066-1070,共5页Xiang-Yang Zhang Feng Liu Yan Chen Wei-Chun Guo Zhao-Hui Zhang 
supported by the National Nature Science Foundation of China,No.81501053(to YC)
Brain-derived neurotrophic factor(BDNF)has robust effects on synaptogenesis,neuronal differentiation and synaptic transmission and plasticity.The maturation of BDNF is a complex process.Proprotein convertase 1/3(PC1/3...
关键词:cortical neuron ischemia NEUROTROPHIN oxygen-glucose deprivation precursor protein of BRAIN-DERIVED NEUROTROPHIC factor PROPROTEIN CONVERTASE PROPROTEIN CONVERTASE 1/3 
The different relations of PCSK9 and Lp(a) to the presence and severity of atherosclerotic lesions in patients with HeFH
《中国循环杂志》2018年第S01期141-142,共2页Yexuan Cao Huihui Liu Di Sun Jinglu Jin Ruixia Xu Yuanlin Guo Naqiong Wu Sha Li Yan Zhang Jing Sun Jianjun Li 
Background Relations of lipoprotein (a)(Lp[a]) and proprotein convertase substilisin/kexin type 9 (PCSK9) levels to coronary artery disease (CAD) have been well established in general population, while little is known...
关键词:lipoprotein(a) PROPROTEIN CONVERTASE substilisin/kexin type 9 CORONARY artery disease 
酶解褐藻寡糖的分离制备及其脂蛋白调节作用被引量:2
《食品与发酵工业》2018年第12期30-35,共6页陈岩君 窦文芳 李恒 史劲松 许正宏 
采用Isoptericola halotolerans CGMCC 5336褐藻胶裂解酶制备褐藻寡糖,通过液质联用技术(liquid chromatograph-mass spectrometer,LC-MS)对其组成进行初步分析,后经过凝胶色谱柱对其进行分离、纯化,得到4种组分,分别命名为Fr1、Fr2、Fr...
关键词:褐藻寡糖 凝胶分离 低密度脂蛋白受体(low-density-lipoprotein receptor LDLR) 前蛋白转化酶枯草溶菌素9(proprotein CONVERTASE subtilisin/kexin type 9 PCSK9) 
Value of serum PCSK9 for evaluating the severity in patients with type 2 diabetes mellitus and atherosclerosis
《Journal of Hainan Medical University》2017年第3期40-43,共4页Ji Ma Hong-Xia Shuai Juan Xiao 
National Natural Science Foundation of China(81601373).
Objective:To study the value of serum PCSK9 for evaluating the severity in patients with type 2 diabetes mellitus and atherosclerosis. Methods:Type 2 diabetic patients with carotid atherosclerosis who were treated in ...
关键词:Type 2 diabetes MELLITUS CAROTID ATHEROSCLEROSIS PROPROTEIN CONVERTASE SUBTILISIN kexin 9 Oxidative stress 
ABO血型与血脂和PCSK9相关性研究被引量:2
《中国心血管病研究》2016年第6期501-507,共7页高莹 李莎 徐瑞霞 郭远林 张彦 朱成刚 吴娜琼 孙静 李建军 
国家自然科学基金,首都临床特色应用研究基金,首都医学发展科研基金,北京自然科学基金,高等学校博士学科点专项科研基金
目的 探讨ABO血型和前蛋白转化酶枯草杆菌蛋白酶9(PCSK9)水平之间的联系.方法 人选507例行诊断性或治疗性冠状动脉造影检查的患者,收集基线数据并用ELISA法评价血浆PCSK9水平.结果 非O型受试者与O型受试者相比,总胆固醇(TC)[(5.07...
关键词:前蛋白转化酶枯草杆菌蛋白酶9 血脂 ABO血型 冠状动脉疾病 PROPROTEIN CONVERTASE subtilisin/kexin type 9 
Inhibition of EGFR Suppresses Ethyl Alcohol and Tobacco Cell Effects on Growth of Human Oral Keratinocytes and Human Papillomavirus 16 Entry as a Function of Furin
《Journal of Cancer Therapy》2015年第1期90-108,共19页Joel L. Schwartz Alexander Munaretto Sirlata Bagchi David Crowe Gonzalo Izaguirre 
Background: Reported are increased risks for malignant transformation in human oral keratinocytes (HOK) from ethyl alcohol (ETOH), tobacco products or human papilloma virus oncogenic subtype 16 (HPV 16) infections. We...
关键词:Ethyl Alcohol Tobacco Poly-Cyclic Aromatic Hydrocarbons Nitrosamines DNA Damage Tumor Suppressor Oncogene HPV 16 FURIN PROPROTEIN CONVERTASE EGFR INHIBITORS Phospho-L-Tyrosine INHIBITORS 
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