RNAINTERFERENCE

作品数：14被引量：33H指数：3
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相关领域：生物学医药卫生更多>>
相关作者：刘丹丹王莉佳杨琴卢光琇田代印更多>>
相关机构：重庆医科大学中南大学江苏省农业科学院更多>>
相关期刊：《现代生物医学进展》《重庆医科大学学报》《Acta Biochimica et Biophysica Sinica》《Neural Regeneration Research》更多>>
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Advances and prospects of RNA delivery nanoplatforms for cancer therapy
《Acta Pharmaceutica Sinica B》2025年第1期52-96,共45页Mohamed S.Attia Gregor Kijanka Nam-Trung Nguyen Jun Zhang Hongjie An 
support from the Australian Research Council Future Fellowship(No.FT180100361,Australia);Discovery Project(No.DP230100556,Australia);support from Australian Laureate Fellowship(FL230100023,Australia).
Modern oncology is rapidly evolving,driven by recent advances in RNA-based therapeutics.As new emerging cutting-edge technology,mRNA vaccines hold excellent promise for encoding immunostimulatory molecules,tumor-assoc...
关键词：Cancer therapy mRNA vaccine RNAINTERFERENCE Nanoplatforms Gene delivery IMMUNOTHERAPIES Gene silencing Neoantigens 
Matrix metalloproteinase 2 contributes to adult eclosion and immune response in the small hive beetle,Aethina tumida
《Insect Science》2024年第3期733-747,共15页Lixian Wu Yajing Xu Liangbin Li Dainan Cao Fang Liu Hongxia Zhao 
funded by GDAS Special Project of Science and Technology Development(2022GDASZH-2022010106);National Natural Science Foundation of China(Grant No.32200405),Guangzhou Basic and Applied Basic Research Foundation(202201010255);Guangdong Basic and Applied Basic Research Foundation(2021A1515012102,2021A1515010630);Science and Technology Planning Project of Yunfu City(2022020425).
During the pupal-adult eclosion process of holometabolous insects,the old cuticle is shed and replaced by a completely different new cuticle that requires tanning and expansion,along with extensive extracellular matri...
关键词：Aethina tumida adult eclosion immune response matrix metalloproteinase RNAINTERFERENCE 
Molecular and functional characterization of a candidate sex pheromone receptor OR1 in Spodoptera fitura被引量：7
《Insect Science》2017年第4期543-558,共16页Qin-Hui Zhang Zhong-Nan Wu Jing-Jiang Zhou Yong-Jun Du 
This study was funded by the Special Fund for Agro- scientific Research in the Public Interest in China （Grant No. 201203036）, Natural Science Foundation of Zhejiang （Project No. D3080388） and National 973 Project （Project No. 2012CB11410005）.
Olfaction is primarily mediated by highly specified olfactory receptors （ORs）. Here, we cloned and identified an olfactory receptor, named SlituOR1 （Genbank no. JN835269）, from Spodoptera litura and found evidence...
关键词：electroantennogram （EAG） individual variation in situ hybridization ol-factory receptor （9Z  11E）-tetradecadienyl acetate （9Z  12E）-tetradecadienyl acetate RNAINTERFERENCE 
Identification of a novel cytochrome P450 CYP321B1 gene from tobacco cutworm （Spodoptera litura） and RNA interference to evaluate its role in commonly used insecticides被引量：3
《Insect Science》2017年第2期235-247,共13页Rui-Long Wang Keyan Zhu-Salzman Scott R. Baerson Xiao-Wei Xin Jun Li Yi-Juan Su Ren-Sen Zeng 
Insect cytochrome P450 monooxygenases （CYPs or P450s） play an important role in detoxifying insecticides leading to resistance in insect populations. A polyphagous pest, Spodoptera litura, has developed resistance t...
关键词：CYP321B1 cytochrome P450 monooxygenases insecticide resistance RNAINTERFERENCE Spodoptera litura 
Construction of a RNA Interference Vector of Brassica napus L.Pyruvate Kinase Gene
《Agricultural Science & Technology》2014年第5期745-750,共6页付三雄 张超 陈松 周晓婴 戚存扣 
Supported by Natural Science Foundation of Jiangsu Province(BK2011668);Special Fund for Independent Innovation of Agricultural Science and Technology in Jiangsu Province[CX(10)406];Opening Project of the Key Lab of Biology of Oil Crops of Ministry of Agriculture(201001);National 948 Project of China(2011-G23)~~
A predominantly expressed gene, pyruvate kinease （PK） gene, control ing oil accumulation, had been identified in previous study. To construct a PK RNAi vector, a 498-bp target PK gene sequence was amplified and tran...
关键词：Brassicanapus L. Pyruvatekinase （PK） RNAINTERFERENCE Vector construction 
Auxin biosynthesis by the YUCCA6 flavin monooxygenase gene in woodland strawberry被引量：10
《Journal of Integrative Plant Biology》2014年第4期350-363,共14页Hong Liu Wei-Fa Xie Ling Zhang Victoriano Valpuesta Zheng-Wen Ye Qing-Hua Gao Ke Duan 
the Science and Technology Commission of Shanghai Municipality (Shanghai Rising-Star Program (09QA1405300) to K. D., Key Program (12391901400) to Q. H. G.);Shanghai Academy of Agricultural Sciences (S & T Development Program (2012(13)) to K. D.). V. V. was funded by MICINN (Spain), grant no. BIO2010-15630
Auxin has been regarded as the main signal molecule coordinating the growth and ripening of fruits in strawberry, the reference genomic system for Rosaceae. The mechanisms regulating auxin biosynthesis in strawberry a...
关键词：Auxin biosynthesis Fragaria vesta plant development RNAINTERFERENCE YUCCA genes 
Two hydroxypyruvate reductases encoded by OsHPR1 and OsHPR2 are involved in photorespiratory metabolism in rice被引量：4
《Journal of Integrative Plant Biology》2014年第2期170-180,共11页Nenghui Ye Guozhen Yang Yan Chen Chan Zhang Jianhua Zhang Xinxiang Peng 
supported by the National Natural Science Foundation of China (U1201212; 31170222);the Shenzhen Overseas Talents Innovation and Entrepreneurship Funding Scheme (The Peacock Scheme);China Postdoctoral Science Foundation (2013M530374)
Mutations in the photorespiration pathway dis- play a lethal phenotype in atmospheric air, which can be fully recovered by elevated C02. An exception is that mutants of peroxisomal hydroxypyruvate reductase （HPR1） d...
关键词：PHOTORESPIRATION hydroxypyruvate reductase RNAINTERFERENCE alternative splicing rice （Oryza sativa L.） 
Oxygen-glucose deprivation of neurons transfected with toll-like receptor 3-siRNA Determination of an optimal transfection sequence被引量：2
《Neural Regeneration Research》2013年第34期3233-3240,共8页Guiyun Cui Xiaopeng Wang Xinchun Ye Jie Zu Kun Zan Fang Hua 
supported by the National Natural Science Foundation of China,No.30970995;the Postgraduate Science Research Innovation Project of Higher Learning University of Jiangsu Province in China,No.CXLX11_0735
Toll-like receptor 3 protein expression has been shown to be upregulated during cerebral ische- mia/reperfusion injury in rats. In this study, rat primary cortical neurons were subjected to oxy- gen-glucose deprivatio...
关键词：neural regeneration brain injury Toll-like receptor 3 small interfering RNA primary neurons ischemia/reperfusion injury TRANSFECTION HYPOXIA LIPOSOME immune/inflammatory reactions RNAINTERFERENCE grants-supported paper NEUROREGENERATION 
Down-regulation of MTA1 protein leads to the inhibition of migration, invasion, and angiogenesis of non-small-cell lung cancer cell line被引量：2
《Acta Biochimica et Biophysica Sinica》2013年第2期115-122,共8页Shuhai Li Hui Tian Weiming Yue Lin Li Cun Gao Libo Si Wenjun Li Wensi Hu Lei Qi Ming Lu 
This work was supported by the grants from the National Natural Science Foundation of China （3057Ig44）; the Natural Science Foundation of Shandong Province （2009ZRB14005）; and the Independent Innovation Foundation of Shandong University.
Metastasis-associated protein 1 （MTA1） high expression has been detected in a wide variety of human aggressive tumors and plays important roles in the malignant biological behaviors such as invasion, metastasis, and...
关键词：metastasis-associated protein 1 RNAINTERFERENCE ANGIOGENESIS non-small-cell lung cancer 
Identification of a novel C-type lectin from the shrimp Litopenaeus vannamei and its role in defense against pathogens infection被引量：1
《Chinese Journal of Oceanology and Limnology》2011年第5期942-951,共10页罗展 张继泉 李富花 张晓军 柳承璋 相建海 
Supported by the National Basic Research Program of China (973 Program) (No. 2006CB101804);the National Natural Science Foundation of China (No. 30972245);Public Industry (Agriculture) Specific Research Program (No. 200803012)
Acting as one of the pattern recognition receptors （PRRs）, C-type lectin is believed to mediate pathogen recognition and plays an important role in the clearance of pathogens as part of the innate immune system. In ...
关键词：Litopenaeus vannamei innate immune pattern recognition receptor C-type lectin RNAinterference （RNAi） recombinant expression 
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