BIOTHERAPEUTICS

作品数：8被引量：13H指数：2
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Fighting type 2 diabetes: Formulation strategies for peptide-based therapeutics被引量：1
《Acta Pharmaceutica Sinica B》2022年第2期621-636,共16页Carlos Bendicho-Lavilla Iria Seoane-Viano Francisco J.OteroEspinar Asteria Luzardo-Alvarez 
funded by Xunta de Galicia grant number GRC2013/015 and GPC2017/015(Spain)。
Diabetes mellitus is a major health problem with increasing prevalence at a global level.The discovery of insulin in the early 1900 s represented a major breakthrough in diabetes management,with further milestones bei...
关键词：Type 2 diabetes mellitus Glucagon-like peptide-1 receptor agonists EXENATIDE Subcutaneous administration Amylin mimetics Drug delivery systems BIOTHERAPEUTICS Peptide delivery Controlled-release formulations Microparticles Nanoparticles 
Insights into biological therapeutic strategies for COVID-19
《Fundamental Research》2021年第2期166-178,共13页Xiaolong Tian Cheng Li Yanling Wu Tianlei Ying 
the National Key R&D Program of China(2019YFA0904400);National Natural Science Foundation of China(81822027,81630090,81902108);National Megaprojects of China for Major Infectious Diseases(2018ZX10101003-005-010).
The worldwide pandemic of novel coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)that emerged in late December 2019 requires the urgent development of therapeutic ...
关键词：COVID-19 SARS-CoV-2 BIOTHERAPEUTICS Viral entry Viral replication Cytokine storm 
Noveome Biotherapeutics完成1500万美元D轮融资
《健康大视野》2019年第8期11-11,共1页
近日,总部位于美国宾夕法尼亚州的Noveome Biotherapeutics,宣布完成1500万美元D轮融资。自2000年成立以来,Noveome Biotherapeutics已累计筹集超过1.44亿美元的资金,投资者包括美国国防部、宾夕法尼亚州联邦政府、阿勒格尼县政府以及...
关键词：融资 联邦政府 国防部 投资者 美国 
Therapeutic applications of genetic code expansion被引量：7
《Synthetic and Systems Biotechnology》2018年第3期150-158,共9页Yujia Huang Tao Liu 
We thank the following agencies for financial support on related ongoing projects in our lab:National Key Research and Development Program of China(No.2016YFA0201400);the National Natural Science Foundation of China(21778005);Peking University Health Science Center(BMU20160537 and BMU2017QQ006);Youth Thousand-Talents Program of China。
In nature,a limited,conservative set of amino acids are utilized to synthesize proteins.Genetic code expansion technique reassigns codons and incorporates noncanonical amino acids(ncAAs)through orthogonal aminoacyltRN...
关键词：Genetic code expansion Noncanonical amino acids BIOTHERAPEUTICS Antibody-drug conjugates Live-attenuated vaccines 
Indian Spices and Biotherapeutics in Health and Chronic Disease
《Health》2018年第4期374-380,共7页Ian James Martins 
The acceleration in the rate of chronic disease that involves insulin resistance has become of concern in various countries. The rate of the most prevalent chronic diseases involves the metabolic syndrome and non alco...
关键词：SPICES BIOTHERAPEUTICS 
Pharmacokinetics and toxicology of therapeutic proteins:Advances and challenges被引量：3
《World Journal of Biological Chemistry》2012年第4期73-92,共20页Yulia Vugmeyster Frank-Peter Theil Leslie A Khawli Michael W Leach 
Significant progress has been made in understanding pharmacokinetics (PK),pharmacodynamics (PD),as well as toxicity profiles of therapeutic proteins in animals and humans,which have been in commercial development for ...
关键词：PHARMACOKINETICS TOXICOLOGY Therapeutic proteins BIOTHERAPEUTICS MONOCLONAL ANTIBODIES 
Frontier of therapeutic antibody discovery:The challenges and how to face them被引量：1
《World Journal of Biological Chemistry》2012年第12期187-196,共10页Zhi-Jian Lu Su-Jun Deng Da-Gang Huang Yun He Ming Lei Li Zhou Pei Jin 
Therapeutic monoclonal antibodies have become an important class of modern medicines.The established technologies for therapeutic antibody discovery such as humanization of mouse antibodies,phage display of human anti...
关键词：Antibody BIOTHERAPEUTICS BIOPHYSICAL property BISPECIFIC HUMANIZATION Immunogenicity Transgenic RODENT PHAGE display Yeast 
Monoclonal antibody:the corner stone of modern biotherapeutics被引量：1
《药学学报》2012年第10期1275-1280,共6页XIA Zhi-nan CAI Xue-ting CAO Peng 
Worldwide sales of biologic drugs exceeded 100 billion USD in 2011.About 32% is from therapeutic monoclonal antibody(mAb).With many blockbuster biopharmaceutical patents expiring over the next decade,there is a great ...
关键词：monoclonal antibody biotherapeutic BIOSIMILAR biobetter 
第一张基因转殖动物生产蛋白质新药的许可证GTC Biotherapeutics
《臺灣經濟研究月刊》陳政忻 
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