supported by the National Natural Science Foundation of China(82022038)。
Guanosine-based hydrogels have attracted considerable attention because of their simplicity and easy preparation.However,the sugar moiety limits its further applications because of the necessity of sugar in the hydrog...
supported by grants from the National Natural Science Foundation of China(Nos.22277072 and 22107065);"Clinic Plus"Outstanding Project(Nos.2021ZYB009 and 2021ZYB003)from Shanghai Key Laboratory for Nucleic Acid Chemistry Nanomedicine;Innovative research team of high-level local universities in Shanghai.
Nucleic acids are the hereditary information storage medium of life. Due to its high programmability and good biocompatibility, the applications of nucleic acids are not limited to their natural function. However, the...
supported by the National Natural Science Foundation of China[grant numbers 12174009,11974031,12104082,12234002,and 92250303];Beijing Natural Science Foundation[grant number Z220008];N.M.gratefully acknowledges financial support from the Czech Ministry of Education,Youth,and Sports[grantnumbers LTT17015,LM2018114,and EF16_013/0001552].
The identification of the decay pathway of the nucleobase uracil after being photoexcited by ultraviolet light has been a long-standing problem.Various theoretical models have been proposed but yet to be verified.Here...
supported by the National Key Research and Development Program of China(2017YFA0503900);Shenzhen Government’s Plan of Science and Technology(JCYJ20170412110504956);the Shenzhen Fundamental Research Program(JCYJ20200109114225087);the National Science Fund for Distinguished Young Scholars(81525026);the Guangdong Key Laboratory for Functional Substances in Medicinal Edible Resources and Healthcare Products(2021B1212040015).
(±)-Cyclopeltains A and B(1 and 2),two pairs of unusual alkylated adenine derivatives,were isolated from the insect Cyclopelta parva and structurally characterized.1 and 2 both possess a 6/5/7/5 ring system arising f...
This work is supported by the Singapore Ministry of Education under MOE Tier 1 RG178/15 and MOE Tier 1 RG100/15. C. X. C. thanks the support by the National Young 1000 Talent Plan of China and the Shanghai Municipal Natural Science Foundation (No. 16ZR1402500). M. E. appreciates the support by National Synergetic Innovation Center for Advanced Materials (SICAM), the start-up fund by Nanjing Tech University, and Jiangsu 100 Talent.
Two-dimensional transition metal dichalcogenides (2D TMDs) possess a tunable excitonic light emission that is sensitive to external conditions such as electric field, strain, and chemical doping. In this work, we re...
The Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20115103110009);"211"Project Double-Support Plan of Sichuan Agricultural Un iversity(Grant No.03570313);Modernization of Chinese Traditional Medicines in Hainan Province(Grant No.ZY201410)
Determination of nucleosides and nucleobases is important for the quality control of Fritillaria unibracteata Hsiao et K.C. Hsia var. wabuensis (FUW) due to their physiological and pharmacological actions. In the pr...
In this paper we have designed a biosensor device built from B-N substituted graphene nanoribbon within density functional based tight-binding (DFTB) framework. We have investigated the interaction of the nucleobases ...
This work was supported by grants from the Ministry of Science and Technology of China (2009CBl19101), the Ministry of Agriculture of China (2010ZX08010-002), and the National Natural Science Foundation of China (91017010) to H.G.We thank Dr Zhigang Jiang and Dr Di Guo for manu- script preparation and critical discussion, and Dr Shuhua Yang (China Agricultural University, China), Dr Dong Liu (Tsinghua University, China), and Dr Thomas Schm~lling (Free University of Berlin, Germany) for kindly providing the cytokinin mutants and relevant transgenic plants. We thank Dr Xiangning Jiang (Beijing Forestry University, China) and Dr Meiping Zhao (Peking University, China) for their assis- tance on cytokinin quantification, and Meng Ke (Tsinghua University, China) for guidance on bioinformatics. No conflict of interest declared.
In plants, the cytokinin metabolic processes, including cytokinin biosynthesis, interconversion, inactivation, and degradation, play critical roles in the regulation of cytokinin homeostasis and plant development. Pur...
This work was supported by the National Natural Science Foundation of China (No.20903104, No.2107320L and No.20733005) and the Chinese Academy of Sciences.
Pentachlorophenol, a widespread environmental pollutant that is possibly carcinogenic to humans, is metabolically oxidized to tetrachloroquinone (TCBQ) which can result in DNA damage. We have investigated the photoc...
supported by the National Natural Science Foundation of China (20727001 and 30870591);the National Basic Research Program of China (973, 2007CB815205);the Chinese Academy of Sciences through the Hundred Talent Fund
Canonical Watson-Crick base pairs and four representative mismatched base pairs have been studied by quantum chemical computations. Detailed anharmonic vibrational analysis was carried out to reveal some vibrational s...