financially supported by the National Key Research and Development Program of China(grant no.2023YFF1105300).
Consumption of fried foods is highly prevalent in the Western dietary pattern.Western diet has been unfavorably linked with high risk of developing cardiovascular diseases.Heart failure(HF)as a cardiovascular disease ...
Introduction: Malaria control needs the development of complementary and/or alternative strategies such as biological controls. Despite, malaria’s current control efforts, the spread and the emergence of insecticide ...
supported by the National R&D program of China(2022YFC2703500);the Science and Technology Program of Guangzhou,China(202201020292 and 2023A03J0258);the Natural Science Foundation of Shandong Province(ZR2021ZD33);the Strategic Collaborative Research Program of the Ferring Institute of Reproductive Medicine,Ferring Pharmaceuticals and Chinese Academy of Sciences(FIRMC181101).
Environmental factors such as diet and lifestyle can influence the health of both mothers and offspring.However,its transgenerational transmission and underlying mechanisms remain largely unknown.Here,using a maternal...
the ANR JCJC“QuailHeatE”Research Program[ANR-15-CE02-0009–01].
Background In the current context of global warming,thermal manipulation of avian embryos has received increasing attention as a strategy to promote heat tolerance in avian species by simply increasing the egg incubat...
supported by grants from the National Key R&D Program of China No.2020YFA0803900(Hui Wang);the National Natural Science Foundation of China No.81973405(Dan Xu),No.82122071(Dan Xu),and No.82030111(Hui Wang)。
The formation of learning and memory is regulated by synaptic plasticity in hippocampal neurons.Here we explored how gestational exposure to dexamethasone,a synthetic glucocorticoid commonly used in clinical practice,...
The occurrence of transgenerational epigenetic inheritance has overwhelming evidence in plants and invertebrates;however,the substantial erasure of DNA and histone modifications during early embryogenesis has been con...
supported by the National Key Research and Development Program of China (2019YFA0802600);the National Natural Science Foundation of China (31930019,31900442,32200431);the Strategic Priority Research Program“Biological basis of aging and therapeutic strategies”of the Chinese Academy of Sciences (XDB39010400);the China Postdoctoral Science Foundation (2022M713053)。
Argonaute proteins generally play regulatory roles by forming complexes with the corresponding small RNAs(s RNAs).An expanded Argonaute family with 20 potentially functional members has been identified in Caenorhabdit...
supported by the Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(No.SMSEGL20SC02);the National Natural Science Foundation of China(No.41977371);a Project grant from the Shenzhen and Technology Innovation Commission(No.JCYJ20170818094137791);supported by the National Institute of Environmental Health Sciences of the National Institutes of Health under award number 1R15ES032936-01.
Benzo[a]pyrene(BaP),a ubiquitous pollutant,raises environmental health concerns due to induction of bone toxicity in the unexposed offspring.Exposure of F0 ancestor medaka(Oryzias latipes)to 1μg/L BaP for 21 days cau...
supported by the National Natural Science Foundation of China(U20A2030,32025028,and 32188102);the Central Public-interest Scientific Institution Basal Research Fund(Y2022QC20);the Hainan Yazhou Bay Seed Laboratory(#B21HJ0215);the Agricultural Science and Technology Innovation Program of the Chinese Academy of Agricultural Sciences(CAAS-ZDRW202001).
In hybrid plants,heterosis often produces large,vigorous plants with high yields;however,hybrid seeds are generated by costly and laborious crosses of inbred parents.Apomixis,in which a plant produces a clone of itsel...
Transgenerational epigenetic inheritance in mammals remains a debated subject. Here, we demonstrate that DNA methylationof promoter-associated CpG islands (CGIs) can be transmitted from parents to their offspring in m...