NEUTROPHILIC

作品数：25被引量：52H指数：4
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相关领域：医药卫生更多>>
相关作者：薛春生周世文刘世杰赵海金叶艳梅更多>>
相关机构：第三军医大学新桥医院重庆医科大学西南医科大学南方医科大学南方医院更多>>
相关期刊：《Journal of Biophysical Chemistry》《Acta Biochimica et Biophysica Sinica》《Chinese Medical Sciences Journal》《Synthetic and Systems Biotechnology》更多>>
相关基金：国家自然科学基金国家教育部博士点基金更多>>
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Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients:A Multicenter and Clinicopathological Study
《Research》2025年第1期320-332,共13页Mengqi Fan Erfei Song Yuying Zhang Pengfei Zhang Bing Huang Kaixuan Yan Wah Yang Subrata Chakrabarti Hema Mahajan Sen Yan Ying Xu Shuang Hua Wei Liu Cunchuan Wang Aimin Xu Dewei Ye 
financially supported by NSFC(82374171 and 81570701);the Natural Science Foundation of Guangdong Province(2024A1515012945);the Key Laboratory of Model Animal Phenotyping and Basic Research in Metabolic Diseases(2018KSYS003).
Metabolic dysfunction-associated steatohepatitis(MASH)is the progressive form of metabolic dysfunction-associated steatotic liver disease(MASLD),and closely associated with a high risk of liver-related morbidity and m...
关键词：hepatic neutrophils enhanced neutrophil infiltration neutrophilic crown structures morbidly obese clinicopathological study bariatric surgery 
Intrinsically bioactive and biomimetic nanoparticle-derived therapies alleviate asthma by regulating multiple pathological cells被引量：2
《Bioactive Materials》2023年第10期12-26,共15页Jiajun Cai Hui Tao Huan Liu Yi Hu Songling Han Wendan Pu Lanlan Li Gang Li Chenwen Li Jianxiang Zhang 
supported by the National Natural Science Foundation of China(Nos.81971727 and 32271451);the Program for Scientific and Technological Innovation Leader of Chongqing(No.CQYC20210302362);the Program for Distinguished Young Scholars of TMMU,and the Graduate Supervisor Team Program of Chongqing in 2022.
Asthma is a serious global public health concern. Airway neutrophilic inflammation is closely related to severe asthma, for which effective and safe therapies remain to be developed. Here we report nanotherapies capab...
关键词：Neutrophilic asthma Nanotherapy Neutrophil extracellular traps INFLAMMASOME Precision therapy 
Directed evolution of a neutrophilic and mesophilic methanol dehydrogenase based on high-throughput and accurate measurement of formaldehyde被引量：2
《Synthetic and Systems Biotechnology》2023年第3期386-395,共10页Jin Qian Liwen Fan Jinxing Yang Jinhui Feng Ning Gao Guimin Cheng Wei Pu Wenjuan Zhou Tao Cai Shuang Li Ping Zheng Jibin Sun Depei Wang Yu Wang 
the National Key Research and Development Program of China(2018YFA0901500);the National Natural Science Foundation of China(32070083 and 32222004);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2021177);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-008);the Innovation Fund of Haihe Laboratory of Synthetic Biology.
Methanol is a promising one-carbon feedstock for biomanufacturing,which can be sustainably produced from carbon dioxide and natural gas.However,the efficiency of methanol bioconversion is limited by the poor catalytic...
关键词：Methanol dehydrogenase Formaldehyde biosensor Directed evolution C1 bioconversion Methanol oxidation METHYLOTROPHY 
Neutrophilic Panniculitis Associated With Myelodysplastic Syndrome/Myeloproliferative Neoplasm:A Case Report and Literature Review被引量：1
《International Journal of Dermatology and Venereology》2023年第3期168-171,共4页Alexa J.Cohen Laura K.Gleason Safiyyah A.Bhatti Neda Nikbakht 
supported by a grant from the National Cancer Institute(R03CA252818 to NN).
Introduction:Neutrophilic panniculitis(NP)is a rare subtype of neutrophilic dermatosis,a group of neutrophilrich inflammatory skin disorders that can present in association with myeloid neoplasms.NP is defined by the ...
关键词：neutrophilic panniculitis myelodysplastic syndrome neutrophilic dermatoses 
Triple hit to the kidney-dual pathological crescentic glomerulonephritis and diffuse proliferative immune complexmediated glomerulonephritis: A case report
《World Journal of Clinical Cases》2022年第32期11869-11876,共8页Dalia Ibrahim Sergey V Brodsky Anjali A Satoskar Laura Biederman Natallia Maroz 
BACKGROUND Anti-glomerular basement membrane(GBM)disease is a rare rapidly progressive glomerulonephritis,frequently associated with alveolar hemorrhage in the lungs and involving the kidney by crescentic glomerulonep...
关键词：Anti-glomerular basement membrane disease Anti-neutrophilic antibody-associated glomerulonephritis Diffuse proliferative glomerulone-phritis Immune complex mediated glomerulonephritis Case report 
Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis被引量：7
《Acta Pharmacologica Sinica》2022年第4期963-976,共14页Ling Yang Yun Zheng Yu-meng Miao Wen-xin Yan Yan-zhi Geng Yue Dai Zhi-feng Wei 
This work was supported by the National Natural Science Foundation of China(No.81773970);the 2019 Outstanding Young Backbone Teacher Project of Jiangsu University“Green Blue Project”.
Bergenin is a natural PPARγ agonist that can prevent neutrophil aggregation, and often be used in clinics for treating respiratory diseases. Recent data show that Th17 cells are important for neutrophil aggregation a...
关键词：immunity-related diseases neutrophilic asthma Th17 differentiation GLUTAMINOLYSIS GLS1 BERGENIN 
Dysregulated neutrophilic cell death in SLE:a spotlight on ferroptosis被引量：2
《Signal Transduction and Targeted Therapy》2021年第12期3375-3376,共2页Kim Ohl Thomas Rauen Klaus Tenbrock 
In the recent issue of Nature Immunology,Li et al.present a mechanistic insight into neutrophilic cell death and its role in systemic lupus erythematosus(SLE).1 Several groups reported an altered neutrophil function a...
关键词：DEATH NEUTROPHIL PEROXIDATION 
Eighty-year-old man with rare chronic neutrophilic leukemia caused by CSF3R T618I mutation:A case report and review of literature
《World Journal of Clinical Cases》2020年第24期6337-6345,共9页Ya-Ping Li Na Chen Xian-Mei Ye Yong-Shou Xia 
BACKGROUNDChronic neutrophilic leukemia (CNL) is a rare bone marrow proliferative tumorand a heterogeneous disorder. In 2016, the World Health Organization includedactivating mutations in the CSF3R gene as one of the ...
关键词：Chronic neutrophilic leukemia LEUKEMIA Hyperplasia of interstitial neutrophil system CSF3R Case report HYDROXYUREA ALLOPURINOL 
Role of immunodeficiency in Acinetobacter baumannii associated pneumonia in mice
《Chinese Medical Journal》2020年第18期2161-2169,共9页Ai-Ran Liu Wen-Jing Du Jian-Feng Xie Jing-Yuan Xu Ying-Zi Huang Hai-Bo Qiu Yi Yang 
supported by grants from the National Natural Science Foundations of China(No.81300060);Specialized Research Fund for the Doctoral Program of Higher Education of China(No.20130092120070)。
Background:Acinetobacter baumannii(A.baumannii)has become one of the most important opportunistic pathogens inducing nosocomial pneumonia and increasing mortality in critically ill patients recently.The interaction be...
关键词：Acinetobacter baumannii Compromised immunity Dendritic cells Helper T cell Neutrophilic granulocytes PNEUMONIA 
Leukocyte adhesion defect:Where do we stand circa 2019?被引量：2
《Genes & Diseases》2020年第1期107-114,共8页Jhumki Das Avinash Sharma Ankur Jindal Vaishali Aggarwal Amit Rawat 
Migration of polymorphonuclear leukocytes from bloodstream to the site of inflammation is an important event required for surveillance of foreign antigens.This trafficking of leukocytes from bloodstream to the tissue ...
关键词：Neutrophilic defect Neutrophilic leukocytosis Phagocyte rolling PHAGOCYTES Primary immunodeficiency disorders 
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