OROSOMUCOID

作品数:11被引量:35H指数:4
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相关领域:医药卫生更多>>
相关机构:河南理工大学第二军医大学东南大学南京医科大学更多>>
相关期刊:《Current Medical Science》《World Journal of Critical Care Medicine》《Journal of Traditional Chinese Medicine》《Journal of Animal Science and Biotechnology》更多>>
相关基金:国家自然科学基金更多>>
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From gene identifications to therapeutic targets for asthma:Focus on great potentials of TSLP,ORMDL3,and GSDMB
《Chinese Medical Journal Pulmonary and Critical Care Medicine》2023年第3期139-147,共9页Youming Zhang 
Asthma is a chronic respiratory disease,and clinically,asthma exacerbations remain difficult to treat.The disease is caused by combinations of and interactions between genetic and environmental factors.Genomic and gen...
关键词:ASTHMA Thymic stromal lymphopoietin(TSLP) Orosomucoid-like 3(ORMDL3) Gasdermin B(GSDMB) Therapeutic targets 
Evaluation of IFIT3 and ORM1 as Biomarkers for Discriminating Active Tuberculosis from Latent Infection被引量:2
《Current Medical Science》2022年第6期1201-1212,共12页Bing-fen YANG Fei ZHAI Shan YU Hong-juan AN Zhi-hong CAO Yan-hua LIU Ruo WANG Xiao-xing CHENG 
supported by grants from the Thirteen-Fifth Mega-Scientific Project on“Prevention and Treatment of AIDS,Viral Hepatitis and Other Infectious Diseases”(No.2017ZX10201301-007-002);the National Natural Science Foundation of China(No.82072233).
Objective Current commercially available immunological tests cannot be used for discriminating active tuberculosis(TB)from latent TB infection.To evaluate the value of biomarker candidates in the diagnosis of active T...
关键词:TUBERCULOSIS BIOMARKER latent tuberculosis infection interferon-induced protein with tetratricopeptide repeats 3 orosomucoid 1 
The adipokine orosomucoid alleviates adipose tissue fibrosis via the AMPK pathway被引量:4
《Acta Pharmacologica Sinica》2022年第2期367-375,共9页Peng-yuan Wang Jia-yi Feng Zhen Zhang Yi Chen Zhen Qin Xian-min Dai Jie Wei Bo-han Hu Wei-dong Zhang Yang Sun Xia Liu 
This study was supported by grants from the National Natural Science Foundation of China(Nos.81773726,82073907,and 82073842);the Shanghai Science and Technology Innovation Action Plan(Nos.20ZR1470100,18431900800,and 20S11902700);the National Science&Technology Major Project“Key New Drug Creation and Manufacturing Program,China(No.2018ZX09711002-003-015).
The excess deposition of underlying extracellular matrix (ECM) in adipose tissue is defined as adipose tissue fibrosis that is a major contributor to metabolic disorder such as obesity and type 2 diabetes. Anti-fibros...
关键词:ORM adipose tissue FIBROSIS AMPK TGF-β1 3T3-L1 fibroblasts dorsomorphin obesity metabolic disorders 
Orosomucoid in liver diseases
《World Journal of Gastroenterology》2021年第45期7739-7747,共9页Gulsum Ozlem Elpek 
In this editorial,the roles of orosomucoid(ORM)in the diagnoses and follow-up assessments of both nonneoplastic diseases and liver tumors are discussed with respect to the publication by Zhu et al presented in the pre...
关键词:OROSOMUCOID Alpha-1-acid glycoprotein Viral hepatitis CIRRHOSIS Hepatocellular carcinoma DOWNREGULATION 
Orosomucoid-like protein 3,rhinovirus and asthma被引量:4
《World Journal of Critical Care Medicine》2021年第5期170-182,共13页You-Ming Zhang 
The genetic variants of orosomucoid-like protein 3(ORMDL3)gene are associated with highly significant increases in the number of human rhinovirus(HRV)-induced wheezing episodes in children.Recent investigations have b...
关键词:ASTHMA Intercellular adhesion molecule 1 Orosomucoid-like protein 3 Rhinovirus infection SPHINGOLIPIDS 
维生素D受体激活剂治疗早期糖尿病肾病及对尿orosomucoid水平的影响被引量:7
《广东医学》2020年第24期2502-2505,共4页周雪红 刘曙艳 李勇峰 王辉辉 
焦作市医学科研项目(2017KY018)。
目的探究维生素D受体激活剂帕立骨化醇治疗早期糖尿病肾病的效果及对尿类黏蛋白(orosomucoid)水平的影响。方法将收治的120例早期糖尿病肾病患者随机分为帕立骨化醇组、药物对照组各60例,帕立骨化醇组患者使用帕立骨化醇进行治疗,药物...
关键词:帕立骨化醇 糖尿病肾病 肾功能 血糖水平 
Downregulation of orosomucoid 2 acts as a prognostic factor associated with cancer-promoting pathways in liver cancer被引量:9
《World Journal of Gastroenterology》2020年第8期804-817,共14页Han-Zhang Zhu Wei-Jiang Zhou Ya-Feng Wan Ke Ge Jun Lu Chang-Ku Jia 
Supported by Medicine and Health Science and Technology Plan Projects of Zhejiang Province,No.2018KY569;Zhejiang Provincial Natural Science Foundation of China,No.LY17H030002
BACKGROUND Liver cancer has a high mortality and morbidity rate throughout the world.In clinical practice,the prognosis of liver cancer patients is poor,and the complex reasons contribute to treatment failures,includi...
关键词:Orosomucoid gene Specific expression DOWNREGULATION Prognostic factor Tumor promoter signaling Immune suppression 
Estrogen weakens muscle endurance via estrogen receptor-MAPK mediated orosomucoid suppression
《中国药理学与毒理学杂志》2017年第10期974-974,共1页Peng-yuan WANG Xia LIU 
Gender differences in fatigue,manifesting as female more prone to feel exhausted with lower muscle endurance,still remains unclear mechanism.Here,we investigated whether orosomucoid,an endogenous anti-fatigue protein ...
关键词:ESTROGEN MAPK OROSOMUCOID 
Regulation of cytokine gene expression by orosomucoid in neonatal swine adipose tissue
《Journal of Animal Science and Biotechnology》2016年第3期403-411,共9页Timothy G.Ramsay Margo J.Stoll Le Ann Blomberg Thomas J.Caperna 
Background: Porcine adipose tissue expresses orosomucoid(ORM1) mRNA, a protein with anti-inflammatory and immunomodulatory properties. Previous research has demonstrated that porcine ORM1 can reduce insulin stimula...
关键词:Adipose Cytokines Neonate Orosomucoid Swine 
Effect of Gubenfangxiao decoction on respiratory syncytial virus-induced asthma and expression of asthma susceptibility gene orosomucoid 1-like protein 3 in mice被引量:8
《Journal of Traditional Chinese Medicine》2016年第1期101-106,共6页Huang Zhengguang Gao Lijuan Zhao Xia Ling Hao Chen Wenjun 
Supported by Natural Science Foundation of China(Effect of Gubenfangxiao Decoction on the Expression of Asthma Susceptibility Gene ORMDL3 and ADAM33 and its Signaling pathway,No.81173209)
OBJECTIVE: To investigate the effect of Gubenfangxiao decoction (GBFXD) on respiratory-syncytial-virus (RSV) -induced asthma and the expression of asthma susceptibility gene, orosomucoid 1-1ike protein 3 (ORMDL3...
关键词:ASTHMA ORMDL3 protein  mouse Air-way remodeling Gubenfangxiao decoction 
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