OSSEOINTEGRATION

作品数：120被引量：337H指数：10
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相关领域：医药卫生更多>>
相关作者：龚树生李永新郑雅丽张强谢畅更多>>
相关机构：首都医科大学南方医科大学第三附属医院温州医科大学重庆医科大学更多>>
相关期刊：《Journal of Wuhan University of Technology(Materials Science)》《Science China(Life Sciences)》《Regenerative Biomaterials》《Transactions of Nonferrous Metals Society of China》更多>>
相关基金：国家自然科学基金中国博士后科学基金重庆市自然科学基金国家教育部博士点基金更多>>
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Bioactive mineralized small intestinal submucosa acellular matrix/PMMA bone cement for vertebral bone regeneration被引量：1
《Regenerative Biomaterials》2023年第1期957-967,共11页Xinbao Miao Shuhui Yang Jinjin Zhu Zhe Gong Dongze Wu Juncong Hong Kaiwen Cai Jiying Wang Xiangqian Fang Jiye Lu Guoqiang Jiang 
supported by Medical Science and Technology Project of Zhejiang Province[2023RC027];the Natural Science Foundation of Ningbo[202003N4281];the Youth Talent Cultivation Program of the Affiliated Hospital of Medical School of Ningbo University[FYQM-LC-202005];GA created with BioRender.com.
Polymethylmethacrylate(PMMA)bone cement extensively utilized for the treatment of osteoporotic vertebral compression fractures due to its exceptional handleability and mechanical properties.Nevertheless,the clinical a...
关键词：PMMA bone cement mineralized small intestinal submucosa mechanical properties osteogenic differentiation OSSEOINTEGRATION 
CaP-coated Zn-Mn-Li alloys regulate osseointegration via influencing macrophage polarization in the osteogenic environment被引量：2
《Regenerative Biomaterials》2023年第1期1096-1110,共15页Huifen Qiang Caiyao Hou Yujue Zhang Xin Luo Jun Li Chunxiu Meng Kun Liu Zhaoyong Lv Ximeng Chen Fengzhen Liu 
supported by the Science Foundation of Shandong Province of China[Grant No.ZR2021MH026,ZR2022MH075];Medicine and Health Science Technology Development plan of Shandong Province of China[Grant No.202108020440,2020Q127];Liaocheng Key Research and Development Plan of Shandong Province of China[Grant No.2022YDSF16,2022YDSF21];Liaocheng People’s Hospital Youth Fund Project[Grant No.LYQN201914].
Immune response is an important factor in determining the fate of bone replacement materials,in which macrophages play an important role.It is a new idea to design biomaterials with immunomodulatory function to reduce...
关键词：Zn-Mn-Li alloys CaP coatings macrophages polarization OSTEOINTEGRATION inflammation 
A novel biomimetic trabecular bone metal plate for bone repair and osseointegration被引量：2
《Regenerative Biomaterials》2023年第1期423-431,共9页Zhijie Ma Baoyi Liu Shuqiang Li Xiaohu Wang Jingyu Li Jiahui Yang Simiao Tian Chengjun Wu Dewei Zhao 
supported by the National Natural Science Foundation of China[82172398];Dalian Medical Key Specialty‘Dengfeng Plan’Construction Project and China Postdoctoral Science Foundation[2022M720616].
Fracture is one of the most common traumatic diseases in clinical practice,and metal plates have always been the first choice for fracture treatment because of their high strength.However,the bone plates have high ela...
关键词：FRACTURE trabecular bone metal bone plate bone repair OSSEOINTEGRATION 
Advances in osseointegration of biomimetic mineralized collagen and inorganic metal elements of natural bone for bone repair被引量：2
《Regenerative Biomaterials》2023年第1期808-829,共22页Wenbo Zhu Chao Li Mengxuan Yao Xiumei Wang Juan Wang Wei Zhang Wei Chen Hongzhi Lv 
supported by the National Natural Science Foundation of China(grant no.82102584);the National Key R&D Program of China(grant no.2020YFC1107601).
At this stage,bone defects caused by trauma,infection,tumor,or congenital diseases are generally filled with autologous bone or allogeneic bone transplantation,but this treatment method has limited sources,potential d...
关键词：mineralized collagen bone defect reconstruction inorganic metal elements clinical applications 
Degradation behavior and osseointegration of Mg-Zn-Ca screws in different bone regions of growing sheep:a pilot study被引量：2
《Regenerative Biomaterials》2023年第1期1-14,共14页Romy Marek Hanna C´wieka Nicholas Donohue Patrick Holweg Julian Moosmann Felix Beckmann Iva Brcic Uwe Yacine Schwarze Kamila Iskhakova Marwa Chaabane Sandra Sefa Berit Zeller-Plumhoff Annelie-Martina Weinberg Regine Willumeit-Ro¨mer Nicole Gabriele Sommer 
supported by the European Training Network‘Promoting patient safety by a novel combination of imaging technologies for biodegradable magnesium implants,MgSafe’(Horizon 2020 Marie Skłodowska-Curie Action(MSCA)grant No.811226(www.mgsafe.eu))and the Laura Bassi Center of Expertise BRIC(Bioresorbable Implants for Children,FFG,Austria);This research was supported in part through the Maxwell computational resources operated at DESY。
Magnesium(Mg)-based implants are highly attractive for the orthopedic field and may replace titanium(Ti)as support for fracture healing.To determine the implant-bone interaction in different bony regions,we implanted ...
关键词：biodegradable implants magnesium-based alloys computed tomography Mg-Zn-Ca SHEEP HISTOLOGY 
Promoting osteointegration effect of Cu-alloyed titanium in ovariectomized rats
《Regenerative Biomaterials》2022年第1期143-155,共13页Xiyue Zhang Hui Liu Ling Li Cuishan Huang Xiangbo Meng Junzuo Liu Xueling Bai Ling Ren Xinluan Wang Ke Yang Ling Qin 
supported by the Key Program for Foreign Cooperation of Chinese Academy of Sciences[grant number 174321KYSB20180006];the National Natural Science Foundation of China[grant number 51631009];the International Cooperation Program of Shenzhen Science and Technology Innovation Commission(grant number GJHZ20190821160803823).
Osteoporosis is a common skeletal disease making patients be prone to the osteoporotic fracture.However,the clinical implants made of titanium and its alloys with a poor osseointegration need a long time for healing a...
关键词：copper-alloyed titanium alloy OSTEOPOROSIS implant OSSEOINTEGRATION VASCULARIZATION 
Titanium alloy composited with dual-cytokine releasing polysaccharide hydrogel to enhance osseointegration via osteogenic and macrophage polarization signaling pathways被引量：3
《Regenerative Biomaterials》2022年第1期372-388,共17页Yaping Wang Zujian Feng Xiang Liu Chunfang Yang Rui Gao Wenshuai Liu Wenbin Ou-Yang Anjie Dong Chuangnian Zhang Pingsheng Huang Weiwei Wang 
supported by the National Natural Science Foundation of China(32171380,31971306);Natural Science Fund for Distinguished Young Scholars of Tianjin(21JCJQJC00020);CAMS Innovation Fund for Medical Sciences(No.2021-I2M-1-065,2021-I2M-1-058);Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(NO.2019-F40-SYS)and Tianjin Innovation and Promotion Plan Key Innovation Team of Implantable and Interventional Biomedical Materials.
Titanium alloy has been widely used in orthopedic surgeries as bone defect filling.However,the regeneration of high-quality new bones is limited due to the pro-inflammatory microenvironment around implants,resulting i...
关键词：HYDROGEL composite scaffold bone regeneration cytokine delivery macrophage polarization 
Microarchitecture of titanium cylinders obtained by additive manufacturing does not influence osseointegration in the sheep
《Regenerative Biomaterials》2021年第4期11-20,共10页Louis Rony Eric Aguado Bruno Verlee Florence Pascaretti-Grizon Daniel Chappard 
This work was supported partially by the Walloon Region(CWALity project NEXTBONE:Convention n_1610093).This work was made possible by grants from the CHU of Angers(University hospital),project MOCONA and the French Ministry of Research.
Large bone defects are a challenge for orthopedic surgery.Natural(bone grafts)and synthetic biomaterials have been proposed but several problems arise such as biomechanical resistance or viral/bacterial safety.The use...
关键词：TITANIUM trabecular scaffold OSSEOINTEGRATION geometric architecture HISTOMORPHOMETRY 
Characterization and evaluation of a femtosecond laser-induced osseointegration and an anti-inflammatory structure generated on a titanium alloy被引量：1
《Regenerative Biomaterials》2021年第2期104-117,共14页Yang Liu Zhongying Rui Wei Cheng Licheng Song Yunqiang Xu Ruixin Li Xizheng Zhang 
The authors acknowledge financial support from the National Natural Science Foundation of China(11972198,31470935 and 11432016).
Cell–material interactions during early osseointegration of the bone–implant interface are critical and involve crosstalk between osteoblasts and osteoclasts.The surface properties of titanium implants also play a c...
关键词：femtosecond laser hybrid micro-/nanostructure cell–material interactions OSSEOINTEGRATION macrophage polarization 
Efficacy of concentrated growth factors combined with mineralized collagen on quality of life and bone reconstruction of guided bone regeneration被引量：19
《Regenerative Biomaterials》2020年第3期313-320,共8页Yan Dai Xiao-Hui Han Li-Hua Hu Hai-Wei Wu Sheng-Yun Huang Yu-Peng Lu 
funded by China Postdoctoral Science Foundation Grant(No.2019M652380).
To evaluate the clinical efficacy of concentrated growth factors(CGFs)combined with mineralized collagen(MC)in guided bone regeneration(GBR).A retrospective study involving 29 patients treated with GBR technique,which...
关键词：concentrated growth factors mineralized collagen guided bone regeneration bone augmentation OSSEOINTEGRATION 
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