INACTIVATED

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Single-cell multi-omics analysis revealing immune features of inactivated COVID-19 vaccination in systemic lupus erythematosus patients
《Science Bulletin》2025年第1期42-46,共5页Yuxuan Zheng Siyuan Wang Xingyu Zhou Shitong Qiao Xin Zhao Yuan Chen Zijun Li Zhanguo Li Xiaolin Sun Shuguang Tan Jing He George Fu Gao 
supported by the National Key Research and Development Program of China(2022YFC2604100,2022YFC2302900,2021YFC2301400,and 2022YFE0131700);National Natural Science Foundation of China(92169208,32222031,82071813,32141004,and 82171775);Peking University People’s Hospital Research and Development Funds(RDGS2022-05);National Postdoctoral Program for Innovative Talents of China(BX20220332)。
Studies have focused on neutralizing antibody titers and T-cell activation induced by vaccination against different SARS-CoV-2strains[1,2].Advanced single-cell technology has allowed for a comprehensive evaluation of ...
关键词：VACCINATION REVEALING TITER 
COVID-19 infection and inactivated vaccination:Impacts on clinical and immunological profiles in Chinese children with type 1 diabetes
《World Journal of Diabetes》2024年第12期2276-2284,共9页Zhen-Ran Xu Li Xi Jing Wu Jin-Wen Ni Fei-Hong Luo Miao-Ying Zhang 
Supported by National Key Research and Development Program of China,No.2021YFC2701900 and No.2016YFC1305300.
BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has been linked to an increased incidence of diabetes and diabetic ketoacidosis(DKA).However,the relationship between COVID-19 infection and progression to typ...
关键词：COVID-19 infection Diabetic ketoacidosis Type 1 diabetes VACCINATION Immune profiles 
Safety,immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly:a prospective longitudinal study
《Signal Transduction and Targeted Therapy》2024年第6期2738-2747,共10页Hong-Hong Liu Yunbo Xie Bao-Peng Yang Huan-Yue Wen Peng-Hui Yang Jin-E Lu Yan Liu Xi Chen Meng-Meng Qu Yang Zhang Wei-Guo Hong Yong-Gang Li Junliang Fu Fu-Sheng Wang 
supported by Guangzhou Laboratory,Grant Award Number:EKPG21-30-4.
The safety and efficacy of COVID-19 vaccines in the elderly,a high-risk group for severe COVID-19 infection,have not been fully understood.To clarify these issues,this prospective study followed up 157 elderly and 73 ...
关键词：VACCINATION VACCINE doses 
Effect of diabetes mellitus on antibody levels in elderly individuals after vaccination with inactivated SARS-CoV-2 vaccine
《感染控制(英文)》2024年第1期60-67,共8页Wen Guo Yu Cao Yingmei Feng 
Background We explored the influence of diabetes on the antibody levels of elderly individuals after inoculation with an inactivated vaccine against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and the f...
关键词：inactivated vaccine against SARS-CoV-2 DIABETES IgG antibody neutralizing antibody 
Safety and Immunogenicity After Primary and Booster Inactivated SARS-Cov-2 Vaccination in Patients with Autoimmune Liver Diseases
《Journal of Clinical and Translational Hepatology》2024年第2期162-171,共10页Zhiwei Chen Yuting Wang Taiyu He Hu Li Ling Ao Qingbo Pan Yingzhi Zhou Qian Zhu Dejuan Xiang Gaoli Zhang Ning Ling Min Chen Peng Hu Mingli Peng Dachuan Cai Dazhi Zhang Hong Ren 
supported by the National Science and Technology Major Project of China(Nos 2017ZX10202203-007,2017ZX10202203-008,2018ZX10302206-003)and a pilot project of clinical cooperation between traditional Chinese and western medicine for significant and complicated diseases of National Administration of Traditional Chinese Medicine:hepatic fibrosis.We also acknowledge the support of the National Natural Science Foundation of China(No 81772198);Natural Science Foundation of Chongqing,China(No.cstc2020jcyjmsxmX0389).
Background and Aims:SARS-CoV-2 vaccines-associated autoimmune liver diseases have been reported in several case reports.However,the safety and immunogenicity after primary and booster inactivated SARS-CoV-2 vaccinatio...
关键词：SARS-CoV-2 Autoimmune liver disease Inactivated SARS-CoV-2 vaccine SAFETY Antibody responses Memory B cells 
Does the homologous booster with the inactivated coronavirus disease 2019 vaccine work for the omicron variant?Real-world evidence from Jilin,China
《Chinese Medical Journal》2023年第23期2892-2894,共3页Jun Guo Lei Zha Kai Zeng Mingyu Shao Dan Chen Bing Wang Yun Zhou Gang Yang Xue Zhang Xia Zou Yan Zhang Yan Kang 
Key Research and Development Project of the Science and Technology Department of Sichuan Province(No.2021YFS0003,Zygd18020);High-level Talents Fund of the Wuhu Municipal Government(No.2021-134)
To the Editor:The latest variant of concern,Omicron,has become the dominant global variant immediately after it was first reported in November 2021.[1]It contains>30 mutations in the spike protein,with 17 mutations in...
关键词：VACCINATION HOMOLOGOUS RENDERING 
Efficacy of inactivated SARS-CoV-2 vaccination in pediatric hematology/oncology patients:a real-world study
《World Journal of Pediatrics》2023年第10期1017-1021,共5页Jing Miao Jing-Ying Zhang Juan Liang Fen-Ying Zhao Hua Song Wei-Qun Xu Yong-Min Tang Xiao-Jun Xu Qiang Shu 
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has been spreading globally since its initial outbreak in 2019.Substantial evidence has revealed that children who are receiving antitumor therapy or hematopo...
关键词：VACCINATION mortality RESPIRATORY 
Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination among COVID-19 convalescents
《Frontiers of Medicine》2023年第4期747-757,共11页Hao Wang Yu Yuan Bihao Wu Mingzhong Xiao Zhen Wang Tingyue Diao Rui Zeng Li Chen Yanshou Lei Pinpin Long Yi Guo Xuefeng Lai Yuying Wen Wenhui Li Hao Cai Lulu Song Wei Ni Youyun Zhao Kani Ouyang Jingzhi Wang Qi Wang Li Liu Chaolong Wang An Pan Xiaodong Li Rui Gong Tangchun Wu 
supported by the Emergency Key Program of Guangzhou Laboratory(No.EKPG21-30);the Fundamental Research Funds for the Central Universities(No.2019kfyXMBZ015);the Fellowship of China Postdoctoral Science Foundation(Nos.2020T130034ZX and 2020M680102);the National Natural Science Foundation of China(Nos.72061137006 and 82204113).
Emerging SARS-CoV-2 variants have made COVID-19 convalescents susceptible to re-infection and have raised concern about the efficacy of inactivated vaccination in neutralization against emerging variants and antigen-s...
关键词：COVID-19 convalescent SARS-CoV-2 inactivated vaccination neutralizing antibody B cell response 
Dynamic Humoral Immune Response to Primary and Booster Inactivated SARS-CoV-2 Vaccination in Patients with Cirrhosis
《Journal of Clinical and Translational Hepatology》2023年第7期1476-1484,共9页Qian Zhu Lu Wang Xiaoxiao Hu Yingzhi Zhang Tianquan Huang Taiyu He Zhiwei Chen Gaoli Zhang Mingli Peng Min Chen Dachuan Cai Xiaofeng Shi Hong Ren 
supported by the National Science and Technology Major Project of China(2017ZX10202203-007,2017 ZX10202203-008,2018ZX10302206-003);Remarkable Innovation-Clinical Research Project,The Second Affiliated Hospital of Chongqing Medical University and The First batch of key Disciplines On Public Health in Chongqing;support of the National Natural Science Foundation of China(81772198);Natural Science Foundation of Chongqing,China(cstc2020jcyj-msxmX0389).
Background and Aims:Our aim was to determine the immune efficacy of a severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)booster vaccination in cirrhotic patients who had received the primary series.Methods:We...
关键词：SARS-CoV-2 Omicron subvariants CIRRHOSIS Booster dose Humoral response 
Repeated vaccination of inactivated SARS-CoV-2 vaccine dampens neutralizing antibodies against Omicron variants in breakthrough infection被引量：3
《Cell Research》2023年第3期258-261,共4页Bo Gao Liheng He Yujie Bao Yingying Chen Guanzhu Lu Yu Zhang Yingjie Xu Bing Su Jie Xu Ying Wang Leng-Siew Yeap 
This work was supported by funds from the National Key R&D Program of China(2021YFA1301400 to B.S.,Y.X.,L.-S.Y.,and 2021YFC2301500 to Y.W.);the National Natural Science Foundation of China(31722020 to L.-S.Y.,31930035,91942311 and 32061143028 to B.S.);Shanghai Science and Technology Commission(20410714000,20JC410100 and 22JC1402600 to B.S.).
Dear Editor,Since the emergence of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)in 2019,the virus has continued to evolve resulting in new waves of infection and immune escape in the vaccinated populatio...
关键词：VACCINATION ANTIBODIES INFECTION 
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