CELL-FREE

作品数:148被引量:425H指数:12
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相关作者:冉静学孙强李秀军郭晓东侯朝晖更多>>
相关机构:哈尔滨工业大学中国航天科工集团第四研究院北京机电工程总体设计部中央民族大学凯迪迪爱通信技术有限公司更多>>
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Circulating cell-free nucleic acids as prognostic and therapy predictive tools for metastatic castrate-resistant prostate cancer
《World Journal of Clinical Oncology》2020年第7期450-463,共14页Navid Sobhani Marianna Sirico Daniele Generali Fabrizio Zanconati Bruna Scaggiante 
Metastatic castrate-resistant prostate cancer remains a disease hard to cure,and for this reason predictive tools to monitor disease progression and therapy response are an urgent need.In this respect,liquid biopsy on...
关键词:Metastatic castrate-resistant prostate cancer Circulating free deoxyribonucleic acid Cell-free tumor deoxyribonucleic acid Circulating free ribonucleic acid Liquid biopsy Prostate cancer 
Liquid biopsy:expanding the frontier of circulating biomarker discovery and validation in breast cancer
《Cancer Drug Resistance》2019年第4期1215-1223,共9页Philip CMiller Dorraya El-Ashry Marc ELippman 
Our work referenced here was supported by funding from the Breast Cancer Research Foundation(BCRF16098),and by the Prevent Cancer Foundation(M1601095).
Liquid biopsies represent an attractive,minimally-invasive alternative to surgical sampling or complex imaging of breast cancer and breast cancer metastasis.Here we present a summary of the major biomarker components ...
关键词:Liquid biopsy breast cancer cell-free tumor DNA CTC cancer associated fibroblast 
The size of cell-free mitochondrial DNA in blood is inversely correlated with tumor burden in cancer patients被引量:6
《Precision Clinical Medicine》2019年第3期131-139,共9页Qin An Youjin Hu Qingjiao Li Xufeng Chen Jiaoti Huang Matteo Pellegrini Xianghong Jasmine Zhou Matthew Rettig Guoping Fan 
We would like to thank Dr.Anthony E.Sisk Jr.at UCLA Genitourinary Pathology Unit for histological analysis.This study is funded by National Institutes of Health(Grant No:RO1 DE DE025474,P50CA092131,and P50CA211015),and CIRM Stem Cell Genomics Centers of Excellence Award.
Circulating cell-free DNAs(cfDNAs)are fragmented DNA molecules released into the blood by cells.Previous studies have suggested that mitochondria-originated cfDNA fragments(mt-cfDNAs)in cancer patients are more fragme...
关键词:circulating cell-free DNA(cfDNA) tumor burden cancer progression liquid biopsy 
Circulating tumor cells and their role in prostate cancer被引量:1
《Asian Journal of Andrology》2019年第1期24-31,共8页Moritz Maas Miriam Hegemann Steffen Rausch Jens Bedke Arnulf Stenzl Tilman Todenhofer 
Circulating tumor cells (CTC)have become an important biomarker in patients with advanced prostate cancer.CTC count has been demonstrated to be a prognostic factor for overall survival in patients with metastatic cast...
关键词:AR-V7 biomarker CELL-FREE DNA cfDNA CIRCULATING tumor cells CTDNA liquid BIOPSY PROSTATE cancer 
Cell-free DNA integrity for the monitoring of breast cancer:Future perspectives?被引量:2
《World Journal of Clinical Oncology》2018年第2期26-32,共7页Navid Sobhani Daniele Generali Fabrizio Zanconati Marina Bortul Bruna Scaggiante 
Supported by Ricerca Sanitaria 2015 LILT and Beneficentia Foundation Stiftung,No.BEN2016/16
Breast cancer(BC) is the most common cancer and the second cause of death in women worldwide. Therapeutic options are increasing, but the response to treatments is not always efficient and the risk of recurrence cover...
关键词:cfDNA INTEGRITY Liquid BIOPSY BREAST cancer ALU SEQUENCES LINE-1 SEQUENCES 
Application of liquid biopsy in precision medicine: opportunities and challenges被引量:15
《Frontiers of Medicine》2017年第4期522-527,共6页Junyun Wang Shuang Chang Guochao Li Yingli Sun 
Precision medicine for cancer patients aims to adopt the most suitable treatment options during diagnosis and treatment of individuals. Detecting circulating tumor cell (CTC) or circulating tumor DNA (ctDNA) in pl...
关键词:liquid biopsy circulating tumor cells cell-free ctDNA exosomes precision medicine 
Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids被引量:25
《World Journal of Gastroenterology》2017年第31期5650-5668,共19页wataru okajima shuhei komatsu daisuke ichikawa mahito miyamae takuma ohashi taisuke imamura jun kiuchi keiji nishibeppu tomohiro arita hirotaka konishi atsushi shiozaki ryo morimura hisashi ikoma kazuma okamoto eigo otsuji 
Hepatocellular carcinoma(HCC), with its high incidence and mortality rate, is one of the most common malignant tumors. Despite recent development of a diagnostic and treatment method, the prognosis of HCC remains poor...
关键词:Hepatocellular carcinoma BIOMARKER Liquid biopsy Circulating tumor cells Cell-free nucleic acids 
Circulating Tumor DNA as Biomarkers for CancerDetection被引量:9
《Genomics, Proteomics & Bioinformatics》2017年第2期59-72,共14页Xiao Han Junyun Wang Yingli Sun 
supported by the Precision Medicine Research Program of the Chinese Academy of Sciences (Grant No. KJZD-EW-L14);the National Basic Research Program of China (973 Program; Grant Nos. 2012CB518302 and 2013CB911001);the National Natural Science Foundation of China (Grant Nos. 31540033 and 91019024);the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDA01040407)
Detection of circulating tumor DNAs(ct DNAs) in cancer patients is an important component of cancer precision medicine ct DNAs. Compared to the traditional physical and biochemical methods, blood-based ct DNA detectio...
关键词:Precision medicine Liquid biopsy Circulating tumor DNA BIOMARKER Clinical diagnosis Cell-free nucleic acids 
Liquid biopsy in patients with pancreatic cancer: Circulating tumor cells and cell-free nucleic acids被引量:10
《World Journal of Gastroenterology》2016年第25期5627-5641,共15页Taisuke Imamura Shuhei Komatsu Daisuke Ichikawa Tsutomu Kawaguchi Mahito Miyamae Wataru Okajima Takuma Ohashi Tomohiro Arita Hirotaka Konishi Atsushi Shiozaki Ryo Morimura Hisashi Ikoma Kazuma Okamoto Eigo Otsuji 
Despite recent advances in surgical techniques and perioperative management, the prognosis of pancreatic cancer(PCa) remains extremely poor. To provide optimal treatment for each patient with Pca, superior biomarkers ...
关键词:Pancreatic cancer Biomarker LIQUID BIOPSY CIRCULATING tumor cells CELL-FREE nucleic ACIDS 
Cell-free circulating tumor DNA in cancer被引量:16
《Chinese Journal of Cancer》2016年第5期205-213,共9页Zhen Qin Vladimir A.Ljubimov Cuiqi Zhou Yunguang Tong Jimin Liang 
supported partly by the National Natural Science Foundation of China(No.81227901);the Natural Science Basic Research Plan in Shaanxi Province of China(No.2015JZ019);the Fundamental Research Funds for the Central Universities,National Cancer Institute of the National Institutes of Health(No.R00CA138914);National Natural Science Foundation(No. 81372216)
Cancer is a common cause of death worldwide.Despite significant advances in cancer treatments,the morbidity and mortality are still enormous.Tumor heterogeneity,especially intratumoral heterogeneity,is a significant r...
关键词:CIRCULATING TUMOR DNA  Liquid biopsy  CANCER 
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