ENDOTOXIN

作品数:255被引量:1096H指数:16
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相关领域:医药卫生更多>>
相关作者:李兰娟马伟杭吴仲文陈亚岗俞云松更多>>
相关机构:浙江大学医学院附属第一医院复旦大学南京大学大连医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金高等学校学科创新引智计划更多>>
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Fevogrit,a polyherbal medicine,mitigates endotoxin(lipopolysaccharide)-induced fever in Wistar rats by regulating pro-inflammatory cytokine levels
《Animal Models and Experimental Medicine》2025年第4期728-738,共11页Acharya Balkrishna Sonam Sharma Vivek Gohel Rani Singh Meenu Tomer Rishabh Dev Sandeep Sinha Anurag Varshney 
This study was supported by internal funds from Patanjali Research Foundation Trust,Haridwar,India。
Background:Fever is characterized by an upregulation of the thermoregulatory set-point after the body encounters any pathological challenge.It is accompanied by uncomfortable sickness behaviors and may be harmful in p...
关键词:AYURVEDA FEVER Fevogrit LIPOPOLYSACCHARIDE pro-inflammatory cytokines 
Nonlinear proinflammatory effect of short-term PM_(2.5)exposure:A potential role of lipopolysaccharide
《Journal of Environmental Sciences》2024年第2期292-300,共9页Fangxia Shen Mutong Niu Haoxuan Chen Ting Zhang Jing Li Haijie Tong Yan Wu 
supported by the National Natural Science Foundation of China (Nos.42075117 and 41807306)。
The association between PM_(2.5)(particulate matter≤2.5μm)short-term exposure and its health effect is non-linear from the epidemiological studies.And this nonlinearity is suggested to be related with the PM_(2.5)he...
关键词:Fine PM PM_(2.5)pro-inflammatory effects Aerosol health effect ENDOTOXIN Oxidative stress 
Low-dose lipopolysaccharide as an immune regulator for homeostasis maintenance in the central nervous system through transformation to neuroprotective microglia被引量:3
《Neural Regeneration Research》2021年第10期1928-1934,共7页Haruka Mizobuchi Gen-Ichiro Soma 
This work was funded by Control of Innate Immunity Technology Research Association,a grant of Cross-ministerial Strategic Innovation Promotion Program,SIP-No.14533073(to GIS);from the Council for Science from Technology and Innovation(CSTI)in Cabinet Office of Japanese Government and the National Agriculture and Food Research Organization(NARO).
Microglia,which are tissue-resident macrophages in the brain,play a central role in the brain innate immunity and contribute to the maintenance of brain homeostasis.Lipopolysaccharide is a component of the outer membr...
关键词:cognitive impairment ENDOTOXIN LIPOPOLYSACCHARIDE LOW-DOSE MICROGLIA neuroprotection oral administration preconditioning tolerance trained innate immunity 
Adiponectin receptor agonist AdipoRon relieves endotoxin-induced acute hepatitis in mice被引量:2
《Chinese Medical Journal》2019年第20期2438-2445,共8页Wen-Ze Xiao Li Zhang 
Background:Adiponectin is the most abundant adipokines that plays critical roles in the maintenance of energy homeostasis as well as inflammation regulation. The half-life of adiponectin is very short and the small-mo...
关键词:AdipoRon LIPOPOLYSACCHARIDE D-GALACTOSAMINE ACUTE HEPATITIS Apoptosis 
Anti-CD163-dexamethasone conjugate inhibits the acute phase response to lipopolysaccharide in rats被引量:1
《World Journal of Hepatology》2016年第17期726-730,共5页Karen Louise Thomsen Holger Jon Moller Jonas Heilskov Graversen Nils E Magnusson Soren K Moestrup Hendrik Vilstrup Henning Gronbaek 
Supported by The NOVO Nordisk foundation;the Aarhus University Research Foundation;Clinical Institute,Aarhus University,Denmark
AIM: To study the effect of a new anti-CD163-dexamethasone conjugate targeting activated macrophages on the hepatic acute phase response in rats. METHODS: Wistar rats were injected intravenous with either the CD163 ta...
关键词:Acute phase response DEXAMETHASONE ENDOTOXIN Hemoglobin scavenger receptor CD163 Cytokines Inflammation RATS 
An imbalance between innate and adaptive immune cells at the maternal-fetal interface occurs prior to endotoxin-induced preterm birth被引量:6
《Cellular & Molecular Immunology》2016年第4期462-473,共12页Marcia Arenas-Hernandez Roberto Romero Derek St Louis Sonia S Hassan Emily B Kaye Nardhy Gomez-Lopez 
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality worldwide. A transition from an anti-inflammatory state to a pro-inflammatory state in the mother and at the maternal-fetal interface has ...
关键词:antigen-presenting cells effector T cells inflammation LABOR LIPOPOLYSACCHARIDE macrophages microbial product NEUTROPHILS pregnancy preterm labor regulatory T cells 
Novel and disruptive biological strategies for resolving gut health challenges in monogastric food animal production
《Animal Nutrition》2015年第3期138-143,共6页Ming Z.Fan Tania Archbold 
supported by projects funded from the Natural Sciences and Engineering Research Council (NSERC),application #227226-2011 of Canada Discovery Program;the Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA, project #200190)- the University of Guelph Partnership Program (to M.Z. Fan)
Use of feed antibiotics as growth promoters for control of pathogens associated with monogastric food animal morbidity and mortality has contributed to the development of antimicrobial resistance, which has now become...
关键词:Antibiotic Antimicrobial resistance ENDOTOXIN LIPOPOLYSACCHARIDE 
FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation被引量:8
《World Journal of Gastroenterology》2014年第39期14430-14441,共12页Jun Yao Chun-Suo Zhou Xiong Ma Bai-Qing Fu Li-Sheng Tao Miao Chen Ya-Ping Xu 
AIM: To examine the effect of farnesoid X receptor (FXR) activation by GW4064 on endotoxin-induced hepatic inflammation in nonalcoholic fatty liver disease (NAFLD) and the underlying mechanism.
关键词:Farnesoid X receptor Nonalcoholic fatty liver disease GW4064 Nonalcoholic fatty liver disease activity score Lipopolysaccharide-induced hepatic inflammation Macrophage activation 
Protective effect of total flavonoid C-glycosides from Abrus mollis extract on lipopolysaccharide-induced lipotoxicity in mice被引量:8
《Chinese Journal of Natural Medicines》2014年第6期461-468,共8页WANG Yun JIANG Zhen-Zhou CHEN Mi WU Mei-Juan GUO Hong-Li SUN Li-Xin WANG Hao ZHANG Shuang WANG Tao ZHANG Lu-Yong 
supported by the Mega-projects of Science Research for the 11th Five-Year Plan(No.2009ZX09103-315);the 12th Five-Year Plan(No.2013ZX09301-303-003);the 111 Project(No.111-2-07),the 2011’Program for Excellent Scientific;Technological Innovation Team of Jiangsu Higher Education and the Specific Fund for Public Interest Research of Traditional Chinese Medicine,Ministry of Finance(No.200707008);the National Natural Science Foundation of China(No.81172955)
Abrus mollis is a widely used traditional Chinese medicine for treating acute and chronic hepatitis, steatosis, and fibrosis. It was found that the total flavonoid C-glycosides from Abrus mollis extract(AME) showed po...
关键词:Flavonoid C-glycosides ENDOTOXIN Unfolded protein response Lipid metabolism Inflammation 
Alcoholic pancreatitis:A tale of spirits and bacteria被引量:4
《World Journal of Gastrointestinal Pathophysiology》2014年第2期82-90,共9页Alain Vonlaufen Laurent Spahr Minoti V Apte Jean-Louis Frossard 
Alcohol is a major cause of chronic pancreatitis.About5%of alcoholics will ever suffer from pancreatitis,suggesting that additional co-factors are required to trigger an overt disease.Experimental work has implicated ...
关键词:Alcohol PANCREATITIS Fibrosis BACTERIA ENDOTOXIN LIPOPOLYSACCHARIDE 
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