This study was supported by internal funds from Patanjali Research Foundation Trust,Haridwar,India。
Background:Fever is characterized by an upregulation of the thermoregulatory set-point after the body encounters any pathological challenge.It is accompanied by uncomfortable sickness behaviors and may be harmful in p...
supported by the National Natural Science Foundation of China (Nos.42075117 and 41807306)。
The association between PM_(2.5)(particulate matter≤2.5μm)short-term exposure and its health effect is non-linear from the epidemiological studies.And this nonlinearity is suggested to be related with the PM_(2.5)he...
This work was funded by Control of Innate Immunity Technology Research Association,a grant of Cross-ministerial Strategic Innovation Promotion Program,SIP-No.14533073(to GIS);from the Council for Science from Technology and Innovation(CSTI)in Cabinet Office of Japanese Government and the National Agriculture and Food Research Organization(NARO).
Microglia,which are tissue-resident macrophages in the brain,play a central role in the brain innate immunity and contribute to the maintenance of brain homeostasis.Lipopolysaccharide is a component of the outer membr...
Background:Adiponectin is the most abundant adipokines that plays critical roles in the maintenance of energy homeostasis as well as inflammation regulation. The half-life of adiponectin is very short and the small-mo...
Supported by The NOVO Nordisk foundation;the Aarhus University Research Foundation;Clinical Institute,Aarhus University,Denmark
AIM: To study the effect of a new anti-CD163-dexamethasone conjugate targeting activated macrophages on the hepatic acute phase response in rats. METHODS: Wistar rats were injected intravenous with either the CD163 ta...
Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality worldwide. A transition from an anti-inflammatory state to a pro-inflammatory state in the mother and at the maternal-fetal interface has ...
supported by projects funded from the Natural Sciences and Engineering Research Council (NSERC),application #227226-2011 of Canada Discovery Program;the Ontario Ministry of Agriculture, Food and Rural Affairs (OMAFRA, project #200190)- the University of Guelph Partnership Program (to M.Z. Fan)
Use of feed antibiotics as growth promoters for control of pathogens associated with monogastric food animal morbidity and mortality has contributed to the development of antimicrobial resistance, which has now become...
AIM: To examine the effect of farnesoid X receptor (FXR) activation by GW4064 on endotoxin-induced hepatic inflammation in nonalcoholic fatty liver disease (NAFLD) and the underlying mechanism.
supported by the Mega-projects of Science Research for the 11th Five-Year Plan(No.2009ZX09103-315);the 12th Five-Year Plan(No.2013ZX09301-303-003);the 111 Project(No.111-2-07),the 2011’Program for Excellent Scientific;Technological Innovation Team of Jiangsu Higher Education and the Specific Fund for Public Interest Research of Traditional Chinese Medicine,Ministry of Finance(No.200707008);the National Natural Science Foundation of China(No.81172955)
Abrus mollis is a widely used traditional Chinese medicine for treating acute and chronic hepatitis, steatosis, and fibrosis. It was found that the total flavonoid C-glycosides from Abrus mollis extract(AME) showed po...
Alcohol is a major cause of chronic pancreatitis.About5%of alcoholics will ever suffer from pancreatitis,suggesting that additional co-factors are required to trigger an overt disease.Experimental work has implicated ...