supported financially by the Youth Innovation Promotion Association CAS(No.2022375);National Nature Science Foundation of China(No.22171258);the Biological Resources Programme,Chinese Academy of Sciences(No.KFJ-BRP-008);the Sichuan Science and Technology Program(No.2022ZYD0038)。
Increasing interests of difluorinated amino acids(DFAAs)have been raised in recent years due to their widespread bio-organic and medical applications.However,to date,only few investigations focused on their asymmetric...
Chiralα-tertiary amines and related azacycles are commonly found in many natural products,pharmaceuticals and agrochemicals[1].Copper-catalyzed asymmetric propargylic amination(APA)reactions have been established as ...
supported by the National Natural Science Foundation of China(grant no.21901185);funds provided by Tianjin Normal University,China.
Herein,we disclose a ligand-controlled,directing group-assisted strategy to facilitate NiH-catalyzed hydroalkynylation of allyl amides at remoteα-position adjacent to nitrogen and initial olefinic site in a predictab...
Asymmetric catalytic organic synthesis is of profound importance in modern research and industries,providing optically enriched molecules with diverse structures and functions[1].Enzymes,transition metal complexes,and...
the Key Research and Development Program of the Ministry of Science and Technology of China(2023YFA1508600);the start-up funding from Wuhan University.
As a versatile earth-abundant transition metal,Cu has long been widely applied in the C—C and C—X bond forming reactions.As for now,low-valent Cu(Ⅰ)is known to reduce the redox active electrophiles via an SET pathw...
supports were provided by National Key R&D Program of China (2021YFA1500200 and 2021YFF0701600);NSFC (22271249);the Fundamental Research Funds for the Central Universities (226-2022-00224 and 226-2023-00115).
α-Olefins as aliphatic terminal alkenes could be obtained easily from numerous contemporary synthetic reactions as well as petro-chemical industry,and also found in natural products.Compared to the alkenes attaching ...
The well-defined conformational properties of axially chiral compounds bring extraordinary values to an assortment of bioactive molecules,advanced materials,organocatalysts as well as chiral ligands in asymmetric tran...
financial support from NSFC(92056102,21871241);Fundamental Research Funds for the Central Universities(WK2060190086).
Catalytic asymmetric transformations involving carbon-carbon bond cleavages open intriguing strategies for the synthesis of chiral complex molecules.The transient organometallic species mainly generate from the oxidat...
the National Natural Science Foundation of China(No.21673190)for financial support。
The asymmetric transfer hydrogenation(ATH)of a wide range of ketones catalyzed by manganese complex as well as chiral P_(x)N_(y)-type ligand under mild conditions was investigated.Using 2-propanol as hydrogen source,v...
financial supported by the Natural Science Foundation of China(Nos.21722204,21971148);Fok Ying Tung Education Foundation(No.151035)。
A nickel(Ⅱ)-catalyzed asymmetric alkylation of acyclic oxocarbenium ions generated in situ from corresponding acetals with carboxylic acid derivatives to prepareβ-alkoxyl carbonyl moieties with diverseα-substituent...