NANODEVICE

作品数：25被引量：23H指数：3
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相关领域：一般工业技术理学更多>>
相关机构：密歇根州立大学更多>>
相关期刊：《National Science Review》《Science China(Information Sciences)》《International Journal of Extreme Manufacturing》《Science China Chemistry》更多>>
相关基金：国家自然科学基金北京市自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划更多>>
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An aptamer-driven DNA nanodevice for improved delivery of synthetic immunostimulants
《Nano Research》2024年第10期9078-9083,共6页Dejie Lu Zhenghan Di Lele Li Jian Zhao Li Zheng 
supported financially by the National Natural Science Foundation of China(Nos.T2322005 and 32101156);Youth Innovation Promotion Association CAS.
Efficient delivery of therapeutics to immune cells remains a formidable challenge for cancer immunotherapy.In this work,we demonstrate that an aptamer-driven DNA nanodevice,constructed through linkage of a synthetic i...
关键词：APTAMER immunostimulatory oligonucleotides DNA nanodevice tumor-associated macrophages cancer therapy 
An intelligent DNA nanodevice for precision thrombus therapy
《Science China Chemistry》2024年第10期3195-3197,共3页Yihao Zhou Qiangbin Wang 
Obstruction of blood vessels(thrombosis)due to blood clots is one of the main causes of death worldwide and is associated with many cardiovascular diseases,such as myocardial infarction,ischemic stroke,and pulmonary e...
关键词：DRUGS CARDIOVASCULAR ACUTE 
Monitoring of Cell Membrane Microenvironment Based on DNA Nanodevices
《Chemical Research in Chinese Universities》2024年第2期255-267,共13页NAN Hexin CAI Ming KUANG Shi NIE Zhou 
supported by the National Key Research and Development Program of China(Nos.2021YFA0910100,2020YFA0907500);the National Natural Science Foundation of China(Nos.22034002,92253304).
The cell membrane is a critical barrier for cellular homeostasis,integral to signaling and intercellular communication,and vital for understanding cellular functions and disease mechanisms.Investigating its microenvir...
关键词：DNA nanodevice Cell membrane Cellular micro-environment MONITORING 
A Dual Endogenous Stimuli-Responsive Framework Nucleic Acid Nanodevice for MicroRNA Imaging
《CCS Chemistry》2023年第10期2403-2414,共12页Lie Li Haiyan Chen Xiaohong Wen Suping Li Mei Yang Qiuping Guo Kemin Wang 
supported by the Natural Science Foundation of China(grant nos.21877030,21735002,and 21778016).
Framework nucleic acids(FNAs)have emerged as intelligent sensing systems for the detection of tumor-related biomarkers in living cells.However,orthogonally controlled manipulation of FNAs-based nanodevices for on-site...
关键词：framework nucleic acids AND gate activatable biosensor fluorescence microRNA imaging 
An AND-Gate DNA Nanodevice for Dual Protein-Mediated,Tumor-Specific Imaging
《Chinese Journal of Chemistry》2023年第12期1437-1442,共6页Zetan Fan Fangzhi Yu Mingming Yu Lele Li 
financially supported by the Beijing Natural Science Foundation(JQ20005).
Sensitive and specific imaging of tumor-associated biomarkers offers an effective way for cancer diagnosis.However,most of the reported imaging probes are limited to the targeting of a single biomarker,which may impai...
关键词：APTAMER DNA nanodevice Protein Sensor BIOIMAGING 
A smart DNA nanodevice for ATP-activatable bioimaging and photodynamic therapy被引量：1
《Science China Chemistry》2020年第10期1490-1497,共8页Bei Liu Rui Ma Jian Zhao Yuliang Zhao Lele Li 
supported by the National Natural Science Foundation of China(21822401,21805060,21771044);the Young Thousand Talented Program。
Rational design of activatable photosensitizers for controlled generation of singlet oxygen remains a challenge for precise photodynamic therapy(PDT).Herein,we present an aptamer-based nanodevice for adenosine 5′-tri...
关键词：DNA nanotechnology ATP-activatable photodynamic therapy BIOIMAGING 
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