MICROARRAY

作品数：440被引量：1533H指数：15
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MSIsensor-RNA:Microsatellite Instability Detection for Bulk and Single-cell Gene Expression Data
《Genomics, Proteomics & Bioinformatics》2024年第3期85-90,共6页Peng Jia Xuanhao Yang Xiaofei Yang Tingjie Wang Yu Xu Kai Ye 
supported by the National Natural Science Foundation of China(Grant Nos.32070663,32125009,and 62172325);the National Key R&D Program of China(Grant No.2022YFC3400300);the Fundamental Research Funds for the Central Universities,China(Grant No.xzy012020012);the Natural Science Basic Research Program of Shaanxi,China(Grant No.2021GXLH-Z-098)to Kai Ye and Xaiofei Yang.
Microsatellite instability(MSI)is an indispensable biomarker in cancer immunotherapy.Currently,MSI scoring methods by high-throughput omics methods have gained popularity and demonstrated better performance than the g...
关键词：Microsatellite instability Gene expression Single-cell RNA-seq RNA-SEQ MICROARRAY 
JAX-CNV:A Whole-genome Sequencing-based Algorithm for Copy Number Detection at Clinical Grade Level
《Genomics, Proteomics & Bioinformatics》2022年第6期1197-1206,共10页Wan-Ping Lee Qihui Zhu Xiaofei Yang Silvia Liu Eliza Cerveira Mallory Ryan Adam Mil-Homens Lauren Bellfy Kai Ye Charles Lee Chengsheng Zhang 
supported in part by the operational funds from The First Affiliated Hospital of Xi’an Jiaotong University, China;supported by the National Institutes of Health, USA (Grant Nos. U24AG041689 and U54AG052427);supported by the National Natural Science Foundation of China (Grant Nos. 61702406 and 31671372);the National Science and Technology Major Project of China (Grant No. 2018ZX10302205);the National Key R&D Program of China (Grant Nos. 2018YFC0910400 and 2017YFC0907500);the General Financial Grant from the China Postdoctoral Science Foundation (Grant No. 2017M623178);supported in part by the Ewha Womans University Research, South Korea (Grant No. 2018-2019);supported in part by the Connecticut Bio-Innovative Fund, USA
We aimed to develop a whole-genome sequencing(WGS)-based copy number variant(CNV)calling algorithm with the potential of replacing chromosomal microarray assay(CMA)for clinical diagnosis.JAX-CNV is thus developed for ...
关键词：Copy number variant Chromosomal microarray assay Whole-genome sequencing JAX-CNV Genetic testing 
Deep Learning Enabled Microarray Gene Expression Classification for Data Science Applications
《Computers, Materials & Continua》2022年第11期4277-4290,共14页Areej A.Malibari Reem M.Alshehri Fahd N.Al-Wesabi Noha Negm Mesfer Al Duhayyim Anwer Mustafa Hilal Ishfaq Yaseen Abdelwahed Motwakel 
The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work under grant number(RGP 2/42/43);This work was supported by Taif University Researchers Supporting Program(project number:TURSP-2020/200),Taif University,Saudi Arabia.
In bioinformatics applications,examination of microarray data has received significant interest to diagnose diseases.Microarray gene expression data can be defined by a massive searching space that poses a primary cha...
关键词：BIOINFORMATICS data science microarray gene expression data classification deep learning metaheuristics 
rePROBE:Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays
《Genomics, Proteomics & Bioinformatics》2021年第6期1043-1049,共7页Frieder Hadlich Henry Reyer Michael Oster Nares Trakooljul Eduard Muráni Siriluck Ponsuksili Klaus Wimmers 
partly funded by the Leibniz Science Campus Phosphorus Research Rostock;funding from the European Research Area Network on Sustainable Animal Production (ERA-NET Sus An) as part of the PEGa Sus project (Grant No. 2817ERA02D);The Research Institute for Farm Animal Biology (FBN) provided own matched funding
Commercial and customized microarrays are valuable tools for the analysis of holistic expression patterns,but require the integration of the latest genomic information.This study provides a comprehensive workflow impl...
关键词：Mapping MICROARRAY Probe assignment Probe-set annotation Genomic database 
Identification of key genes involved in post-traumatic stress disorder:Evidence from bioinformatics analysis
《World Journal of Psychiatry》2020年第12期286-298,共13页Yao-Yao Bian Li-Li Yang Bin Zhang Wen Li Zheng-Jun Li Wen-Lin Li Li Zeng 
Supported by the National Natural Science Foundation of China,No.81603529,81673982,and 81704084;the Natural Science Foundation of the Jiangsu Higher Education Institutions,No.16KJB360002;the Advantages of the Nursing Discipline Project of Jiangsu Province,No.2019YSHL005;China Scholarship Council,No.201908320373;the Jiangsu Government Scholarship for Overseas Studies;and the Qing Lan Project,No.014000773/2018-00376.
BACKGROUND Post-traumatic stress disorder(PTSD)is a serious stress-related disorder.AIM To identify the key genes and pathways to uncover the potential mechanisms of PTSD using bioinformatics methods.METHODS Gene expr...
关键词：Post-traumatic stress disorder Differentially expressed genes Key pathway Gene-pathway co-expression Bioinformatics analysis MICROARRAY 
Identification of key genes and pathways for Alzheimer's disease via combined analysis of genome-wide expression profiling in the hippocampus
《Biophysics Reports》2019年第2期98-109,共12页Mengsi Wu Kechi Fang Weixiao Wang Wei Lin Liyuan Guo Jing Wang 
In this study, combined analysis of expression profiling in the hippocampus of 76 patients with Alzheimer's disease (AD) and 40 healthy controls was performed. The effects of covariates (including age, gender, postmor...
关键词：Alzheimer's disease Combined analysis HIPPOCAMPUS Gene expression DIFFERENTIALLY EXPRESSED genes MICROARRAY 
dentification of Circular RNAs as a Novel Biomarker for Ovarian Endometriosis被引量：14
《Chinese Medical Journal》2018年第5期559-566,共8页Xiao-Xuan Xu Shuang-Zheng Jia Yi Dai Jun-Ji Zhang Xiao-Yan Li Jing-Hua Shi Jin-Hua Leng Jing-He Lang 
This study was supported by grants from the National Key R＆D Program of China （No. 2017YFC1001200） and National Natural Science Foundation of China （No. 81270681 ）.
Background： Endometriosis is a challenging disease with symptoms such as dysmenorrhea and infertility. However, its etiology is still vague and there is still no effective markers or treatment. This study aimed to pr...
关键词：Circular RNA ENDOMETRIOSIS MICROARRAY MIRNA mRNA 
Exosomal MicroRNA-10a Is Associated with Liver Regeneration in Rats through Downregulation of EphA4被引量：7
《Chinese Medical Journal》2018年第4期454-460,共7页Un Luo Ze-Ping Yu Han Qin Ze-Xin Zhu Ming-Heng Liao Hao-Tian Liao Ke-Fei Yuan Yong Zeng 
This work was supported by grants from the National Natural Science Foundation of China （No. 81672882 and No. 81502441） and Science and Technology Support Program of Sichuan Province （No. 2017SZ0003）.
Background： MicroRNAs （miRNAs） have been reported to play vital roles in liver regeneration. Previous studies mainly focused on the functions of intracellular miRNAs, while the functions of circulating exosomal miR...
关键词：Cell Cycle EphA4 Liver Regeneration MICROARRAY miR-10a 
MicroRNA Profiling of Transgenic Mice with Myocardial Overexpression of Nucleolin
《Chinese Medical Journal》2018年第3期339-346,共8页Qing-Lan Lyu Bi-Mei Jiang Bin Zhou Li Sun Zhong-Yi Tong Yuan-Bin Li Yu-Ting Tang Hui Sun Mei-Dong Liu Xian-Zhong Xiao 
Background：Nucleolin （NCL） is the most abundant RNA-binding protein in the cell nucleolus and plays an important role in chromatin stability,ribosome assembly,ribosomal RNA maturation,ribosomal DNA transcription,nu...
关键词：MicroRNA microarray MYOCARDIUM NUCLEOLIN Transgenic mice 
Development of a 16S r RNA gene-based microarray for the detection of marine bacterioplankton community
《Acta Oceanologica Sinica》2017年第10期106-114,共9页ZHAO Wei WANG Jingjing LIANG Yajie HUANG Zhiyong 
The Science and Technology Support Program of Tianjin Municipal under contract Nos 15ZCZDSF00620 and11ZCKFSY07800;the Open Fund for Priority Discipline of Zhejiang Province under contract No.xkzsc10
A better understanding of bacterioplankton community shifts following change in marine environments is critical to predict the marine ecosystem function. In order to get a snapshot of the microbial taxonomy profiling ...
关键词：microarray bacterioplankton community 16S rRNA gene marine environment 
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