CISPLATIN

作品数:604被引量:1584H指数:17
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相关领域:医药卫生更多>>
相关作者:曾慧慧王夔卢仁泉郭林李强更多>>
相关机构:华中科技大学四川大学北京大学卫生部更多>>
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相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
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Effects of cisplatin in combination with hyperthermia on biological characteristics of retroperitoneal liposarcoma
《Chinese Medical Journal》2021年第9期1110-1112,共3页Gheng-Li Miao Shahbaz Hanif Lin Zhang Xiao-Bing Chen Mei Huang Shi-Bo Liu Cheng-Hua Luo 
supported by a grant from the Beijing Science and Technology Commission(No.Z161100000516025).
Pathologically,retroperitoneal liposarcoma(RPLS)is a group of malignant tumors,which originates from adipose tissue in retroperitoneal space,accounting for almost 70%of all retroperitoneal tumors.RPLS has no optimal t...
关键词:RETROPERITONEAL SARCOMA CISPLATIN 
Assessment on the Efficacy and Safety of Aidi Injection Combined with Vinorelbine and Cisplatin for Treatment of Advanced Nonsmall Cell Lung Cancer被引量:9
《Chinese Medical Journal》2016年第6期723-730,共8页Hua-Ye Zhao Hai-Yan Zhou Yan-Ting Warlg Wei Chen Shu-Ya Qi Jun-Ling Cao Guo-Hui Li 
Background: The aim of this study was to assess the efficacy and safety of vinorelbine and cisplatin (NP chemotherapy) alone or in combination with Aidi injection for the treatment of advanced nonsmall cell lung ca...
关键词:Aidi Injection META-ANALYSIS Nonsmall Cell Lung Cancer Randomized Controlled Trials 
Monitoring the Progression of Renal Fibrosis by T2-weighted Signal Intensity and Diffusion Weighted Magnetic Resonance Imaging in Cisplatin induced Rat Models被引量:4
《Chinese Medical Journal》2015年第5期626-631,共6页Huan-Huan Wu Hui-Ru Jia Yi Zhang Le Liu Dong-Bo Xu Hao-Ran Sun 
This work was supported by grant from Chinese Nature Science Foundation (No. 81171316).
Background:Diffusion weighted imaging (DWI),with the applying of intravoxel incoherent motion model,has showed promising results in obtaining additional information about microperfusion and tubular flow associated ...
关键词:Apparent Diffusion Coefficient Animal Model HISTOPATHOLOGY Chronic Kidney Disease KIDNEY Renal Fibrosis Diffusion Weighted Imaging 
Efficacy of radical cystectomy plus adjuvant intraarterial chemotherapy with gemcitabine and cisplatin on locally advanced bladder cancer被引量:2
《Chinese Medical Journal》2014年第7期1249-1254,共6页Jiang Lijuan Zhang Zhiling Dong Pei Li Yonghong Yao Kai Liu Zhuowei Han Hui Qin Zike Yao Min Zhou Fangjian 
Background Bladder cancer is the ninth most common cancer in the world; fewer than 15% of transitional-cell carcinoma patients survive 2 years if left untreated.Although radical cystectomy is the standard treatment o...
关键词:adjuvant intraarterial chemotherapy adjuvant chemotherapy  bladder cancer radical cystectomy 
Insulin enhances apoptosis induced by cisplatin in human esophageal squamous cell carcinoma EC9706 cells related to inhibition of autophagy被引量:6
《Chinese Medical Journal》2014年第2期353-358,共6页Yang Yang Wen Fengbiao Dang Lifeng Fan Yuxia Liu Donglei Wu Kai Zhao Song 
Background Chemoresistance is common among patients with esophageal squamous cell carcinoma (ESCC).We investigated the effect and mechanism of insulin on enhancing anticancer functions of cisplatin in human esophage...
关键词:esophageal squamous cell carcinoma INSULIN chemotherapy sensitivity AUTOPHAGY APOPTOSIS PI3K/Akt/mTOR signalling pathway 
Inhibition of nuclear factor-κB activity enhanced chemosensitivity to cisplatin in human lung adeno-carcinoma A549 cells under chemical hypoxia conditions被引量:8
《Chinese Medical Journal》2013年第17期3276-3282,共7页LI Fang HUANG Li SU Xiao-li GU Qi-hua HU Cheng-ping 
Background Tumor hypoxia, one of the features of solid tumors, is associated with chemo-resistance. Recently, nuclear factor-KB (NF-κB) was found to be activated during hypoxia. However, the impact of NF-κB activa...
关键词:lung adenocarcinoma nuclear factor-κB chemical hypoxia CHEMOTHERAPY Bcl-2 
Tolerability and toxicity of adjuvant cisplatin and gemcitabine for treating non-small cell lung cancer被引量:4
《Chinese Medical Journal》2013年第11期2087-2091,共5页YANG Fan LI Xiao CHEN Ke-zhong JIANG Guan-chao WANG Jun 
Background The combination of cisplatin and vinorelbine is an evidence-supported regimen for adjuvant chemotherapy for treating non-small cell lung cancer (NSCLC). But this doublet has considerable toxicity and unfa...
关键词:non-small cell lung cancer adjuvant drug therapy TOXICITY TOLERABILITY 
Role of microRNA-181a in the apoptosis of tubular epithelial cell induced by cisplatin被引量:10
《Chinese Medical Journal》2012年第3期523-526,共4页Zhu Han-yu Liu Mo-yan Hong Quan Zhang Dong Geng Wen-jia Xie Yuan-sheng Chen Xiang-mei 
This work was supported by the National Natural Science Foundation of China (No.61101218 and No.81102673),the New Star Program of Beijing Science and Technology Commission (No.2011111) and the National Basic Research Program of China (No.2011 CB944004).
Background Cisplatin (DDP) is one of most effective and most commonly used therapeutic agent in treating tumors,it can accumulate in the kidney and lead to acute renal failure.MicroRNA-181a can induce cell apoptosis...
关键词:MicroRNA-181a CISPLATIN tubular epithelial cell APOPTOSIS 
Long-term outcomes of gemcitabine and cisplatin in patients with recurrent or metastatic esophageal squamous cell carcinoma: a phase Ⅱ trial被引量:11
《Chinese Medical Journal》2011年第23期4012-4017,共6页HUANG Jing FAN Qing-xia CHEN Li LIU Ai-na CAI Rui-gang HAO Xue-zhi WANG Jin-wan SUN Yan 
Background Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Prior studies had demonstrated potential synergistic antitumor activity of gemcitabine in combination with cisplatin. Ther...
关键词:chemotherapy GEMCITABINE CISPLATIN esophageal cancer 
GRP78 upregulation-induced increase in cisplatin sensitivity of SPCA1 lung cancer cells被引量:3
《Chinese Medical Journal》2011年第20期3341-3346,共6页ZHANG Li-chuan WANG Jia-rui ZHAO Long WANG Tao WU Jing FAN Su-fang CHEN Li-xia SHAO Shu-juan Joseph Molnar WANG Qi 
This study was supported by the grant from National Natural Science Foundation of China (No. 81071228 and No. 30670532).
Background Glucose regulated protein 78 (GRP78), an endoplasmic reticulum (ER) chaperone, plays a critical role in chemotherapy resistance in a variety of cancers. In this study, we investigated the up-regulation ...
关键词:GRP78 human lung cancer cell line SPCA1 CISPLATIN CHEMOSENSITIVITY 
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