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作品数:146被引量:280H指数:9
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相关领域:医药卫生更多>>
相关作者:田中宏明曹明张奠湘张瑞泉李世晋更多>>
相关机构:京都大学大连理工大学中国科学院华南植物园清华大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金上海市浦江人才计划项目更多>>
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Shedding light on the retina to see healthy and pathological aging
《Neural Regeneration Research》2025年第12期3537-3538,共2页Marília Inês Móvio Maria Camila Almeida Sergio T.Ferreira Alexandre Hiroaki Kihara 
With the advances in medicine and technology,life expectancy has increased significantly in recent decades.While this is positive news,it also brings major challenges to public health systems.As people live longer,the...
关键词:DISEASES ALZHEIMER cases 
Shedding light on the effects of sodium-glucose cotransporter 2 inhibitors in the early stages of heart failure
《World Journal of Cardiology》2025年第3期96-100,共5页Luigi Falco Emilio Di Lorenzo Daniele Masarone 
Heart failure(HF),which falls outside of the historical macrovascular or microvascular categorizations of diabetes complications,has been overlooked for long time in diabetic patients,despite its increasing prevalence...
关键词:Heart failure Sodium-glucose cotransporter 2 Sodium-glucose cotransporter 2 inhibitors Diabetes complications Glycemic control 
Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope
《Signal Transduction and Targeted Therapy》2024年第9期3566-3568,共3页Qianhui Zhu Pan Liu Shuo Liu Can Yue Xiangxi Wang 
supported by Ministry of Science and Technology of China(CPL-1233 and SRPG22-003);National Key Research and Development Program(2018YFA0900801);CAS(YSBR-010);National Natural Science Foundation of China(NSFC)(32200138);the National Science Foundation Grants(12034006,32325004 and T2394482);supported by National Science Fund for Distinguished Young Scholar(No.32325004);the NSFS Innovative Research Group(No.81921005).
Dear Editor,Multiple waves of outbreaks of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have resulted in unprecedented public health and socioeconomic crises.After 4 years of primary as well as breakthro...
关键词:properties acute respiratory 
Shedding light on pancreatic metastasis of clear cell sarcoma:An exceptional journey
《World Journal of Clinical Cases》2024年第25期5657-5661,共5页Preeti Kumari Chaudhary Soochong Kim 
Supported by National Research Foundation of Korea,No.NRF-2022R1A2C1003638;The Basic Research Lab Program through the NRF of Korea Funded by The Ministry of Science and ICT,No.2022R1A4A1025557.
This editorial comments on the study by Liu et al investigating pancreatic metastasis of clear cell sarcoma(CCS)published in the World Journal of Clinical Cases.CCS is a rare and aggressive melanocytic tumor,that typi...
关键词:Clear cell sarcoma PANCREAS METASTASIS DIAGNOSIS Treatment 
Estimating the effective reproduction number of COVID-19 from population-wide wastewater data:An application in Kagawa,Japan
《Infectious Disease Modelling》2024年第3期645-656,共12页Yuta Okada Hiroshi Nishiura 
Y.O.received funding from the SECOM Science and Technology Foundation,The Kyoto University Foundation,and Fujiwara Memorial Foundation.H.N.received funding from Health and Labour Sciences Research Grants(grant numbers 20CA2024,21HB1002,21HA2016,and 23HA2005);the Japan Agency for Medical Research and Development(grant numbers JP23fk0108612 and JP23fk0108685);JSPS KAKENHI(grant numbers 21H03198 and 22K19670);the Environment Research and Technology Development Fund(grant number JPMEERF20S11804)of the Environmental Restoration and Conservation Agency of Japan,Kao Health Science Research;the Daikin GAP Fund of Kyoto University,the Japan Science and Technology Agency SICORP program(grant numbers JPMJSC20U3 and JPMJSC2105);the RISTEX program for Science,Technology,and Innovation Policy(grant number JPMJRS22B4)。
Although epidemiological surveillance of COVID-19 has been gradually downgraded globally,the transmission of COVID-19 continues.It is critical to quantify the transmission dynamics of COVID-19 using multiple datasets ...
关键词:Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Wastewater-based epidemiology Shedding load distribution'Mathematical model 
Early diagnosis of pancreatic cancer: Shedding light on an unresolved challenge
《World Journal of Clinical Cases》2024年第14期2463-2465,共3页Cristian Lindner 
Diagnosing early-stage pancreatic cancer(PC)remains a clinical challenge.Hence,studying novel imaging aspects that could enhance the diagnostic accuracy of malignant pancreatic precursor lesions is imperative.This art...
关键词:Pancreatic cancer Pancreatic intraepithelial neoplasm High-grade pancreatic intraepithelial neoplasm Pancreatic ducts Cancer Early diagnosis 
Shedding light on gene therapy of Parkinson’s disease in non-human primates
《The Innovation》2024年第2期15-16,共2页Xunyi Yan Xin Jin 
Parkinson’s disease(PD)is a progressive neurodegeneration disease initially described by James Parkinson.It is typically diagnosed based on clinical features such as bradykinesia,resting tremor,rigidity,and,in later ...
关键词:CLINICAL RIGIDITY initially 
Shedding new light on atherosclerosis therapeutics:Nanomedicines targeting atherosclerotic immune microenvironment
《EngMedicine》2024年第3期90-106,共17页Zhiyue Wang Jie Sheng Guangming Lu Longjiang Zhang 
supported by the State Key Laboratory of Analytical Chemistry for Life Science(5431ZZXM2405);National Key Research and Development Program of China(2022YFC2010004);Science and Technology Innovation 2030-Major Projects(2020AAA0109500).
Atherosclerosis(AS)leads to atherosclerotic cardiovascular disease(ASCVD),the predominant cause of death worldwide.As traditional lipid-lowering therapies have encountered a bottleneck in dealing with diverse types of...
关键词:ATHEROSCLEROSIS Immune microenvironment NANOMEDICINE Immunometabolism Imaging Diagnosis Targeted therapy 
Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain:from theory to facts被引量:2
《Neural Regeneration Research》2023年第9期1869-1875,共7页Andreu Matamoros-Angles Behnam Mohammadi Feizhi Song Mohsin Shafiq Santra Brenna Berta Puig Markus Glatzel Hermann C.Altmeppen 
supported by funding from the Creutzfeldt-Jakob Disease Foundation;Inc.(USA);the Alzheimer Forschung Initiative (AFI e.V.,Germany);the Werner-Otto-Stiftung (Hamburg,Germany)(all to HCA);the China Scholarship Council (to FS);European Union’s Horizon 2020 Research and Innovation Program under the Marie Sklodowska-Curie Grant Agreement N°101030402 (to AMA);Deutsche Forschungsgemeinschaft (DFG) Collaborative Research Center (CRC) 877"Proteolysis as a regulatory event in pathophysiology"(to MG)。
In the last decades,the role of the prion protein(PrP) in neurodegenerative diseases has been intensively investigated,initially in prion diseases of humans(e.g., Creutzfeldt-J akob disease) and animals(e.g.,scrapie i...
关键词:ADAM10 aggregation Alzheimer’s disease AMYLOID antibodies Creutzfeldt-Jakob disease enzymatic cleavage extracellular vesicles NEURODEGENERATION NEUROTOXICITY proteolytic processing stroke transmissible spongiform encephalopathies 
Pilomatrixoma causing irreversible peripheral eyebrow shedding:A case report
《Chinese Journal of Plastic and Reconstructive Surgery》2023年第1期30-32,共3页Zeren Shen Fei Cheng Yanqin Dai Yijia Yu Lulu Ye Jinghong Xu 
supported by the Zhejiang Provincial Natural Science Foundation of China (grant nos. LQ22H150005 and LQ21H150005)
Pilomatrixomas are benign tumors derived from hair stromal cells;however,their exact etiology is unknown.A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow,with shedding of...
关键词:PILOMATRIXOMA Eyebrow shedding MICROINFLAMMATION 
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