With the advances in medicine and technology,life expectancy has increased significantly in recent decades.While this is positive news,it also brings major challenges to public health systems.As people live longer,the...
Heart failure(HF),which falls outside of the historical macrovascular or microvascular categorizations of diabetes complications,has been overlooked for long time in diabetic patients,despite its increasing prevalence...
supported by Ministry of Science and Technology of China(CPL-1233 and SRPG22-003);National Key Research and Development Program(2018YFA0900801);CAS(YSBR-010);National Natural Science Foundation of China(NSFC)(32200138);the National Science Foundation Grants(12034006,32325004 and T2394482);supported by National Science Fund for Distinguished Young Scholar(No.32325004);the NSFS Innovative Research Group(No.81921005).
Dear Editor,Multiple waves of outbreaks of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)have resulted in unprecedented public health and socioeconomic crises.After 4 years of primary as well as breakthro...
Supported by National Research Foundation of Korea,No.NRF-2022R1A2C1003638;The Basic Research Lab Program through the NRF of Korea Funded by The Ministry of Science and ICT,No.2022R1A4A1025557.
This editorial comments on the study by Liu et al investigating pancreatic metastasis of clear cell sarcoma(CCS)published in the World Journal of Clinical Cases.CCS is a rare and aggressive melanocytic tumor,that typi...
Y.O.received funding from the SECOM Science and Technology Foundation,The Kyoto University Foundation,and Fujiwara Memorial Foundation.H.N.received funding from Health and Labour Sciences Research Grants(grant numbers 20CA2024,21HB1002,21HA2016,and 23HA2005);the Japan Agency for Medical Research and Development(grant numbers JP23fk0108612 and JP23fk0108685);JSPS KAKENHI(grant numbers 21H03198 and 22K19670);the Environment Research and Technology Development Fund(grant number JPMEERF20S11804)of the Environmental Restoration and Conservation Agency of Japan,Kao Health Science Research;the Daikin GAP Fund of Kyoto University,the Japan Science and Technology Agency SICORP program(grant numbers JPMJSC20U3 and JPMJSC2105);the RISTEX program for Science,Technology,and Innovation Policy(grant number JPMJRS22B4)。
Although epidemiological surveillance of COVID-19 has been gradually downgraded globally,the transmission of COVID-19 continues.It is critical to quantify the transmission dynamics of COVID-19 using multiple datasets ...
Diagnosing early-stage pancreatic cancer(PC)remains a clinical challenge.Hence,studying novel imaging aspects that could enhance the diagnostic accuracy of malignant pancreatic precursor lesions is imperative.This art...
Parkinson’s disease(PD)is a progressive neurodegeneration disease initially described by James Parkinson.It is typically diagnosed based on clinical features such as bradykinesia,resting tremor,rigidity,and,in later ...
supported by the State Key Laboratory of Analytical Chemistry for Life Science(5431ZZXM2405);National Key Research and Development Program of China(2022YFC2010004);Science and Technology Innovation 2030-Major Projects(2020AAA0109500).
Atherosclerosis(AS)leads to atherosclerotic cardiovascular disease(ASCVD),the predominant cause of death worldwide.As traditional lipid-lowering therapies have encountered a bottleneck in dealing with diverse types of...
supported by funding from the Creutzfeldt-Jakob Disease Foundation;Inc.(USA);the Alzheimer Forschung Initiative (AFI e.V.,Germany);the Werner-Otto-Stiftung (Hamburg,Germany)(all to HCA);the China Scholarship Council (to FS);European Union’s Horizon 2020 Research and Innovation Program under the Marie Sklodowska-Curie Grant Agreement N°101030402 (to AMA);Deutsche Forschungsgemeinschaft (DFG) Collaborative Research Center (CRC) 877"Proteolysis as a regulatory event in pathophysiology"(to MG)。
In the last decades,the role of the prion protein(PrP) in neurodegenerative diseases has been intensively investigated,initially in prion diseases of humans(e.g., Creutzfeldt-J akob disease) and animals(e.g.,scrapie i...
supported by the Zhejiang Provincial Natural Science Foundation of China (grant nos. LQ22H150005 and LQ21H150005)
Pilomatrixomas are benign tumors derived from hair stromal cells;however,their exact etiology is unknown.A 31-year-old woman presented with a subcutaneous mass located precisely above the left eyebrow,with shedding of...