云南高校图书馆联盟文献共享服务平台- DECAPENTAPLEGIC

DECAPENTAPLEGIC: 作品数：15被引量：26H指数：3; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：杨斌王桂荣沈杰李志红郭兆安更多>>; 相关机构：中国农业科学院植物保护研究所中国农业大学山东中医药大学山东中医药大学附属医院更多>>; 相关期刊：《Chinese Journal of Integrative Medicine》《World Journal of Gastroenterology》《World Journal of Stem Cells》《World Journal of Traditional Chinese Medicine》更多>>; 相关基金：国家自然科学基金山东省自然科学基金更多>>

Interleukin-17A facilitates tumor progression via upregulating programmed death ligand-1 expression in hepatocellular carcinoma: 《World Journal of Gastrointestinal Oncology》2025年第1期176-198,共23页Zhong-Xia Yang Li-Ting Zhang Xiao-Jun Liu Xue-Bin Peng Xiao-Rong Mao; Supported by the Natural Science Foundation of Gansu Province,No.21JR7RA373 and No.24JRRA295.; BACKGROUND Hepatocellular carcinoma(HCC)is an inflammation-associated tumor with a dismal prognosis.Immunotherapy has become an important treatment strategy for HCC,as immunity is closely related to inflammation in th...; 关键词：INTERLEUKIN-17A Programmed death ligand-1 Interleukin-17A receptor Small mothers against decapentaplegic 2 Hepatocellular carcinoma IMMUNOTHERAPY

Inhibiting Effect and Mechanism of Aconitum tanguticum(Maxim.) Stapf on Intestinal Fibrosis of CCD-18Co Cells: 《World Journal of Traditional Chinese Medicine》2024年第3期354-362,共9页Qin-Dan Cui Li-Dan Shen Yuan Bai Muhammad Azhar Jun Deng Xian-Ju Huang Hai-Ying Tong; supported by grants provided by the National Natural Science Foundation of China (81873090);funding from the Research on Identification and Support Innovation and Development of Enterprise Technology Projects in Hubei Province (2021BLB174);the Modern Transmission and Innovation Research Team of Traditional Chinese Medicine at South Central Minzu University; Objective: The objective of the study was to explore the potential signaling mechanism of Aconitum tanguticum(Maxim.) Stapf(ATS) and its impact on intestinal fibrosis in vitro. Methods: Network pharmacology was used t...; 关键词：Aconitum tanguticum(Maxim.)Stapf CCD‑18Co cells intestinal fibrosis network pharmacology transforming growth factor‑β/suppressor of the mother against decapentaplegic signal pathway

Exosomal let-7a-5p derived from human umbilical cord mesenchymal stem cells alleviates coxsackievirus B3-induced cardiomyocyte ferroptosis via the SMAD2/ZFP36 signal axis: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第5期422-437,共16页Xin LI Yanan HU Yueting WU Zuocheng YANG Yang LIU Hanmin LIU; supported by the China Postdoctoral Science Foundation(No.2022M712252);the Natural Science Foundation of Sichuan Province,China(No.2023NSFSC1634).; Viral myocarditis(VMC)is one of the most common acquired heart diseases in children and teenagers.However,its pathogenesis is still unclear,and effective treatments are lacking.This study aimed to investigate the regu...; 关键词：Exosome Let-7a-5p Mothers against decapentaplegic homolog 2(SMAD2) Coxsackievirus B3(CVB3) Ferroptosis

TGF-β_(1)/Smad信号通路与肾间质纤维化被引量：2: 《生命的化学》2023年第4期601-609,共9页胡欣欣孟晓凡徐圣洁郭兆安; 山东省自然科学基金创新发展联合基金项目(ZR2022LZY005)。; 肾间质纤维化(renal interstitial fibrosis,RIF)是慢性肾脏病(chronic kidney disease,CKD)的主要病理学基础,是CKD进展至终末期肾病的最终共同途径,与肾脏疾病的预后密切相关。RIF是多种信号通路相互作用的结果,其中转化生长因子(tran...; 关键词：肾间质纤维化转化生长因子-β_(1)/small mothers against decapentaplegic 信号通路非编码RNA

Possible mechanisms associated with immune escape and apoptosis on anti-hepatocellular carcinoma effect of Mu Ji Fang granules被引量：1: 《World Journal of Gastrointestinal Oncology》2023年第3期504-522,共19页Yi-Bing Zhang Yong-Rui Bao Shuai Wang Tian-Jiao Li He Tai Jia-Peng Leng Xin-Xin Yang Bo-Cai Wang Xian-Sheng Meng; Supported by National Natural Science Foundation of China,No.81874342;Natural Science Foundation of Liaoning Province,No.2020-MZLH-35.; BACKGROUND Hepatocellular carcinoma(HCC)is one of the most common digestive system cancers with high mortality rates worldwide.The main ingredients in Mu Ji Fang Granules(MJF)are alkaloids,flavonoids,and polysaccharid...; 关键词：Mu Ji Fang granules Hepatocellular carcinoma Transforming growth factorβ1/Mothers against decapentaplegic homolog Immune escape H22 tumor-bearing mice HepG2 cells

飞蝗dpp基因在翅发育中的功能分析: 《山西大学学报（自然科学版）》2022年第6期1632-1639,共8页武兆辰张福斌徐子龙张晶张建珍赵小明; 山西大学第十八期本科生科研训练项目资助(2020018381);国家自然科学基金(31970469,31702067)。; Dpp(Decapentaplegic)是脊椎动物和无脊椎动物中非常重要且高度保守的一个信号通路,在细胞的生长和分化等方面发挥调控作用。在完全变态昆虫中,Dpp调控翅的生长发育,但对渐变态昆虫翅发育的作用机制尚不清楚。文章以飞蝗(Locusta migrat...; 关键词：飞蝗翅发育 DECAPENTAPLEGIC RNA干扰

Regulation of transforming growth factor-β signaling as a therapeutic approach to treating colorectal cancer被引量：4: 《World Journal of Gastroenterology》2022年第33期4744-4761,共18页Jana Maslankova Ivana Vecurkovska Miroslava Rabajdova Jana Katuchova Milos Kicka Michala Gayova Vladimir Katuch; According to data from 2020,Slovakia has long been among the top five countries with the highest incidence rate of colorectal cancer(CRC)worldwide,and the rate is continuing to rise every year.In approximately 80%of C...; 关键词：Small mothers against decapentaplegic homologs Transforming growth factor-beta Colorectal cancer MARKER Signaling pathway

LncRNA-m18as1 competitively binds with miR-18a-5p to regulate follicle-stimulating hormone secretion through the Smad2/3 pathway in rat primary pituitary cells被引量：1: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2022年第6期502-514,共13页Weidi ZHANG Wenzhi REN Dongxu HAN Guokun ZHAO Haoqi WANG Haixiang GUO Yi ZHENG Zhonghao JI Wei GAO Bao YUAN; the National Natural Science Foundation of China(No.31872349)。; Long noncoding RNAs(lncRNAs)are expressed in different species and different tissues,and perform different functions,but little is known about their involvement in the synthesis or secretion of follicle-stimulating ho...; 关键词：Long noncoding RNA(lncRNA) Micro RNA(miRNA) Competitive endogenous RNA(ceRNA) Follicle-stimulating hormone(FSH) Mothers against decapentaplegic homolog 2/3(Smad2/3)

Multiple roles of mothers against decapentaplegic homolog 4 in tumorigenesis, stem cells, drug resistance, and cancer therapy: 《World Journal of Stem Cells》2022年第1期41-53,共13页Chuan-Jing Dai Yu-Ting Cao Fang Huang Yi-Gang Wang; the National Natural Science Foundation of China,No.8180306;the Natural Science Foundation of Zhejiang Province,No.LY18C070002;the 521 Talent Project of Zhejiang Sci-Tech University,No.2021437620 and No.2019337459.; The transforming growth factor(TGF)-βsignaling pathway controls many cellular processes,including proliferation,differentiation,and apoptosis.Abnormalities in the TGF-βsignaling pathway and its components are closel...; 关键词：Cancer therapy Drug resistance Mothers against decapentaplegic homolog 4 STEMNESS Transforming growth factor-β TUMORIGENESIS

Hsa_circRNA_102610 upregulation in Crohn’s disease promotes transforming growth factor-β1-induced epithelial-mesenchymal transition via sponging of hsa-miR-130a-3p被引量：2: 《World Journal of Gastroenterology》2020年第22期3034-3055,共22页Juan Yin Yu-Lan Ye Tong Hu Li-Juan Xu Li-Ping Zhang Ru-Ning Ji Ping Li Qian Chen Jian-Yun Zhu Zhi Pang; Supported by the Suzhou Special Project of Diagnosis and Treatment for Key Clinical Disease,No.LCZX201715;the Natural Science Foundation of Jiangsu Province,No.BK20161232;the Science and Technology Development Fund of Nanjing Medical University,No.NMUB2018215.; BACKGROUND The incidence of inflammatory bowel disease,a chronic intestinal inflammatory disorder that includes Crohn’s disease(CD)and ulcerative colitis,is rising.Circular RNAs are considered valuable diagnostic bio...; 关键词：Hsa_circRNA_102610 Hsa-miR-130a-3p Epithelial-mesenchymal transition Crohn’s disease Mothers against decapentaplegic homolog 4 Transforming growth factor-β1

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