supported by the National Natural Science Foundation of China (No. 81573490, 81872930, 81473273 and 81673505);Natural Science Foundation of Jiangsu Province of China (BK20161457);the "333", "Six Talent Peaks" and "Cyan Blue" Projects of Jiangsu Province
Cinnamic acid and its analogues (pyragrel and ozagrel) undergo chain-shortened (β-oxidative) and reductive metabolism on acyl side chain. In this study, we characterized the β-oxidative and reductive metabolism on a...
Objective:To study the effect of danhong injection combined with sodium ozagrel on serum IL-8, TNF-α, VEGF, TBIL and NSE in old patients with acute cerebral infarction.Methods:A total of 100 old patients with acute c...
Objective:To evaluate the changes in serum index levels after monosialoganglioside injection combined with conventional treatment of neonatal hypoxic ischemic encephalopathy. Methods:A total of 70 children with neonat...
Objective:To explore the clinical efficacy of aspirin in combined with ozagrel sodium in the treatment of acute cerebral infarction (ACI).Methods:A total of 120 patients with ACI who were admitted in our hospital from...
supported by the National Natural Foundation of China(No.31060213);the Research Foundation of Educational Department of Jiangxi Province(No.GJJ13261)
A three-dimensional cobalt coordination polymer [Co(IMPAA)2]n(1, HIMPAA =(2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]acrylic acid) was synthesized with ozagrel and structurally characterized by element analysis, ...
To reduce the first-pass effect and increase the targeting of ozagrel(OZ),the ozagrel -magnetoliposomes(OZ-MLs)were prepared in this study.Here,we described the preparation and characterization of OZ-MLs.It had a diam...
A novel approach to the synthesis of ozagrel is described. The target compound is conveniently prepared from the commercially available material, 1,1-carboxyldiimidazole (CDI) through the condensation and hydrolyzat...