NEUROFILAMENTS

作品数：9被引量：11H指数：2
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相关领域：医药卫生更多>>
相关作者：冯振宇周然王永辉更多>>
相关机构：山西中医学院更多>>
相关期刊：《Neuroimmunology and Neuroinflammation》《Neural Regeneration Research》《Science Bulletin》《Science China(Life Sciences)》更多>>
相关基金：山西省国际科技合作计划山西省回国留学人员科研经费资助项目更多>>
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Insights into spinal muscular atrophy from molecular biomarkers被引量：1
《Neural Regeneration Research》2025年第7期1849-1863,共15页Xiaodong Xing Xinzhu Liu Xiandeng Li Mi Li Xian Wu Xiaohui Huang Ajing Xu Yan Liu Jian Zhang 
supported by the Collaborative Innovation Center for Clinical and Translational Science by Chinese Ministry of Education&Shanghai,No.CCTS-2022205;the“Double World-Class Project”of Shanghai Jiaotong University School of Medicine(both to JZ)。
Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle weakness.It is one of the most common genetic causes of mortality among infants aged less than 2 years.Biomar...
关键词：biomarkers disease progression gene-targeting therapy NEUROFILAMENTS Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes 
Growth associated protein 43 and neurofilament immunolabeling in the transected lumbar spinal cord of lizard indicates limited axonal regeneration被引量：2
《Neural Regeneration Research》2022年第5期1034-1041,共8页Lorenzo Alibardi 
Previous cytological studies on the transected lumbar spinal cord of lizards have shown the presence of differentiating glial cells,few neurons and axons in the bridge region between the proximal and distal stumps of ...
关键词：GAP-43 IMMUNOCYTOCHEMISTRY LIZARD NEUROFILAMENTS regeneration spinal cord 
Current application of neurofilaments in amyotrophic lateral sclerosis and future perspectives被引量：2
《Neural Regeneration Research》2021年第10期1985-1991,共7页Yuri Matteo Falzone Tommaso Russo Teuta Domi Laura Pozzi Angelo Quattrini Massimo Filippi Nilo Riva 
Motor neuron disease includes a heterogeneous group of relentless progressive neurological disorders defined and characterized by the degeneration of motor neurons.Amyotrophic lateral sclerosis is the most common and ...
关键词：amyotrophic lateral sclerosis biomarkers motor neuron disease neurofilament light chain phosphorylated neurofilament heavy chain 
CSF biomarkers in multiple sclerosis:beyond neuroinflammation
《Neuroimmunology and Neuroinflammation》2021年第1期14-41,共28页Simona Toscano Francesco Patti 
For many years,quantifiable biomarkers in neurological diseases have represented a hot topic.In multiple sclerosis(MS),cerebrospinal fluid biomarkers have played a diagnostic role since the introduction of Poser's cri...
关键词：Multiple sclerosis biomarkers cerebrospinal fluid NEUROFILAMENTS oligoclonal bands disease activity 
Detecting neurodegenerative pathology in multiple sclerosis before irreversible brain tissue loss sets in被引量：1
《Translational Neurodegeneration》2019年第1期466-482,共17页Jeroen Van Schependom Kaat Guldolf Marie Béatrice D’hooghe Guy Nagels Miguel D’haeseleer 
Background:Multiple sclerosis(MS)is a complex chronic inflammatory and degenerative disorder of the central nervous system.Accelerated brain volume loss,or also termed atrophy,is currently emerging as a popular imagin...
关键词：Brain atrophy magnetic resonance imaging multiple sclerosis NEURODEGENERATION NEUROFILAMENTS 
Effects of estrogen receptor modulators on cytoskeletal proteins in the central nervous system被引量：2
《Neural Regeneration Research》2017年第8期1231-1240,共10页Julia J.Segura-Uribe Rodolfo Pinto-Almazán Angélica Coyoy-Salgado Claudia E.Fuentes-Venado Christian Guerra-Araiza 
supported by FIS/IMSS project No.FIS/IMSS/PROT/G13/1216;CGA received Beca de Excelencia en Investigación by Fundación IMSS,ACS;JJSU received financial support from CIS/IMSS;CONACy T,RPA received financial support from USC-CONACYT Postdoctoral Scholars Program
Estrogen receptor modulators are compounds of interest because of their estrogenic agonistic/antagonistic effects and tissue specificity. These compounds have many clinical applications, particularly for breast cancer...
关键词：estrogen receptor modulators selective estrogen receptor modulators MICROTUBULES NEUROFILAMENTS TIBOLONE TAMOXIFEN RALOXIFENE 
益气通脉胶囊对脑缺血大鼠学习记忆能力的影响被引量：3
《世界中西医结合杂志》2016年第1期117-120,共4页彭涛 冯振宇 王永辉 周然 
山西省国际科技合作项目(2013081065-1);山西省回国留学人员科研资助项目(2014-088)
目的观察益气通脉胶囊对脑缺血损伤后大鼠学习记忆能力的影响及相关机理研究。方法选择SD大鼠90只,按随机数字表法选择10只作为对照组,其余大鼠采用反复夹闭双侧颈总动脉结合硝普钠降压法复制SD大鼠拟血管性痴呆模型。造模后选存活大鼠5...
关键词：脑缺血 学习记忆 生长相关蛋白43(growth associated protein 43 GAP43) 神经丝蛋白-200(Neurofilaments Protein-200 NF200) 中药复方 
Assembly and structure of neurofllaments isolated from bovine spinal cord
《Science China(Life Sciences)》1999年第3期233-239,共7页佟向军 陈建国 刘洁 庞世瑾 翟中和 
Project supported by the Doetor Foundation of Ministry of Education of China.
Neurofilaments (NFs) are neuron-specific intermediate filaments. The NFs were isolated from bovine spinal cord by differential centrifugation. The NFs were detected with electron microscopy and scanning tunneling micr...
关键词：NEUROFILAMENTS (NFs) STM sidearm STRUCTURE ASSEMBLY immunogold. 
Structure of neurofilaments studied with scanning tunneling microscopy
《Chinese Science Bulletin》1998年第21期1805-1809,共5页Jie Liu Xiangjun Tong Shijin Pang Zhonghe Zhai 
Neurofilaments (NFs) were isolated from bovine spinal cord. The structure of purified NFs was studied by scanning tunneling microscopy (STM). The STM images showed that NF was composed of a long core filament and nume...
关键词：NEUROFILAMENT INTERMEDIATE FILAMENT scanning TUNNELING microscopy. 
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