RALOXIFENE

作品数：38被引量：46H指数：4
导出分析报告
相关作者：黄德芳高玉芬吴志兰陈高翔张雪妹更多>>
相关机构：无锡市第三人民医院复旦大学同济大学附属同济医院中国科学院大学更多>>
相关期刊：《国际眼科杂志》《Acta Pharmacologica Sinica》《中国医学生物技术应用》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in HeLa cells by enhancing the lysosomotropic effect
《BIOCELL》2023年第5期1051-1063,共13页OMER ERDOGAN GULEN MELIKE DEMIRBOLAT OZGE CEVIK 
supported by a Grant(221S945)from the Scientific and Technological Research Council of Turkey(TUBITAK);an Aydin Adnan Menderes University Research Grant(ADU-TPF-20041).
Background:Raloxifene,a selective estrogen receptor modulator,is also known to be a lysosomotropic agent.The bioavailability of raloxifene is around 2%due to extensive hepatic transport.Exosomes are nanosized vesicles...
关键词：APTAMER Autophagy Cervical cancer EXOSOMES RALOXIFENE 
Sequential Treatment Reduces the Acute Phases of Adverse Effect of Zoledronic Acid in First Time Users
《Open Journal of Preventive Medicine》2018年第7期189-205,共17页Jinmei Deng Dongmei Cai Suming Jie Enjing Chen Xiuzhen Cai Yanbing Li 
Objective: To investigate whether sequential regimen such as traditional anti-reabsorption medications followed by zoledronic acid could reduce the side effects after initiation of zoledronic acid in postmenopausal os...
关键词：Zoledronic Acid ALENDRONATE Sodium RALOXIFENE CALCITONIN POSTMENOPAUSAL OSTEOPOROSIS ADVERSE Reaction 
Effects of estrogen receptor modulators on cytoskeletal proteins in the central nervous system被引量：2
《Neural Regeneration Research》2017年第8期1231-1240,共10页Julia J.Segura-Uribe Rodolfo Pinto-Almazán Angélica Coyoy-Salgado Claudia E.Fuentes-Venado Christian Guerra-Araiza 
supported by FIS/IMSS project No.FIS/IMSS/PROT/G13/1216;CGA received Beca de Excelencia en Investigación by Fundación IMSS,ACS;JJSU received financial support from CIS/IMSS;CONACy T,RPA received financial support from USC-CONACYT Postdoctoral Scholars Program
Estrogen receptor modulators are compounds of interest because of their estrogenic agonistic/antagonistic effects and tissue specificity. These compounds have many clinical applications, particularly for breast cancer...
关键词：estrogen receptor modulators selective estrogen receptor modulators MICROTUBULES NEUROFILAMENTS TIBOLONE TAMOXIFEN RALOXIFENE 
Raloxifene hydrochloride treatment leads to better outcomes than medroxyprogesterone acetate when paired with estrogen in ovariectomized cholesterol-fed rabbits
《Acta Biochimica et Biophysica Sinica》2014年第12期1080-1083,共4页Caiyu Zeng Falin Yang Hong He Keqing Hu Xin Wang Qin Hu Jifu Li 
The benefits of estrogen in cardiovascular system include a reduction in low-density lipoprotein cholesterol （LDL-C）, decrease in LDL oxidation, and enhancement of vascular function [1]. Estrogen replacement therapy...
Systematical approach in evaluation of LC method for determination of raloxifene hydrochloride and its impurities employing experimental design
《Journal of Pharmaceutical Analysis》2013年第1期45-52,共8页B.Jani Stojanovi T.Raki B.Slavkovi N.Kosti A.Vemi A.Malenovi 
the Ministry of Education and Science ofthe Republic of Serbia for supporting these investigations through the Project 172052
Method validation presents a detailed investigation of analytical method and provision of the evidence that the method, when correctly applied, produces results that fit to the purpose. In order to achieve the method ...
关键词：Experimental design Method validation Raloxifenehydrochloride IMPURITIES Liquid chromatography 
Neuroprotective Effects of Raloxifene on Aβ_(25-35)-induced Damages in PC12 Cells via Mitogen-activated Protein Kinase Signaling Pathway被引量：1
《Journal of Reproduction and Contraception》2012年第1期1-16,共16页Xue DAI Jie WU Xue-ping SUN Li GAO Yu-gui CUI Jia-yin LIU 
supported by the "Six Talents Peak" of Jiangsu Province,China 973 Program(No.2007CB944005);Science and Technology Development Foundation of Nanjing Medical University(No.2011NJMU152)
Objective To investigate the neuroprotective effects and the mechanism of this protection of raloxifene （RLX）, a selective estrogen receptor modulator.Methods MTT assay and flow cytometry with annexin V-FITC/PI stai...
关键词：RALOXIFENE AΒ25-35 APOPTOSIS MAPK signaling pathway Alzheimer＇s disease mitogen-activated protein kinase （MAPK） 
Combination of raloxifene, aspirin and estrogen as novel paradigm of hormone replacement therapy in rabbit model of menopause被引量：3
《Acta Pharmacologica Sinica》2011年第8期1031-1037,共7页Fa-lin YANG Ke-qing HU Xin WANG Zi-mo LIU Qin HU Ji-fu LI Hong HE 
Acknowledgements This work was supported by Grant from the Natural Science Foundation of Shandong Province, Ji-nan, Shandong, China （#Y2005C50）, Grant-in-Aid for China-Japan Sasagawa Researchers, from the Ministry of Health, Beijing, China （#083）. The authors are grateful to Chun-xi LIU and Zhi YANG for their excellent technical contributions.
Aim： To assess a novel hormone replacement therapy （HRT） paradigm using raloxifene, aspirin combined with estrogen in rabbit model of menopause. Methods： Female New Zealand white rabbits were ovariectomized or sha...
关键词：ESTROGEN RALOXIFENE ASPIRIN ATHEROSCLEROSIS hormone replacement therapy 
Selective Estrogen Receptor Modulator: Raloxifene
《Journal of Reproduction and Contraception》2011年第1期51-60,共10页Xue DAI Jie WU 
Selective estrogen receptor modulators （SERMs） are structurally different com- pounds that interact with intracellular estrogen receptors in target organs as estrogen receptor agonists and antagonists. Raloxifene is...
关键词：selective estrogen receptor modulator （SERM） RALOXIFENE estrogen agonists estrogen antagonists 
Antagonism of estrogen-mediated cell proliferation by raloxifene in prevention of ageing-related prostatic hyperplasia被引量：5
《Asian Journal of Andrology》2010年第5期735-743,共9页Rui Yang Yu-Xia Ma Lin-Feng Chen Ying Zhou Zhan-Po Yang Yan Zhu Xiao-Ling Du Jian-Dang Shi Hong-Shun Ma Ju Zhang 
Acknowledgment This research was funded by the following grants： the National Basic Research Programs, China （973 Programs, No. 2009CB918904, No. 2010CB945003）, the National Natural Science Foundation of China （No. 30872592）, Joint Research Fund for Overseas Chinese Scholars and Scholars in Hong Kong and Macao, China （No. 30928027）, and the key research project of Tianjin Municipal Science and Technology Commission, China （No. 09ZCKFSF00800）.
Estrogen has important roles in the initiation and development of benign prostatic hyperplasia （BPH）. Regulators of the estrogen receptor （ER） are tissue- and cell-specific. We evaluated the effect of estrogen ant...
关键词：ESTROGEN prostatic hyperplasia RALOXIFENE rats 
Protective effect of raloxifene on lipopolysaccharide and acid-induced acute lung injury in rats被引量：3
《Acta Pharmacologica Sinica》2007年第10期1585-1590,共6页Guang-ju ZHOU Hong ZHANG Sheng-de ZHI Guo-ping JIANG Jing WANG Mao ZHANG Jian-xin GAN Shao-wenXU Guan-yu JIANG 
Aim： To evaluate the protective effect of oral raloxifene on acute lung injury. Methods： Thirty adult, male Sprague-Dawley rats each weighing 180-210 g were used and divided into 3 groups： the raloxifene-lipopolysa...
关键词：acute lung injury ASPIRATION fluorodeoxy-glucose LIPOPOLYSACCHARIDE MICROPET pulmonary edema RALOXIFENE 
全选清除导出
共4页<1234>
检索报告 对象比较 聚类工具 使用帮助 返回顶部