Ningbo Public Welfare Science and Technology Plan(Grant No.2019C50089)。
In the present study, we aimed to retrospectively analyze the medication prescriptions of menopausal women diagnosed with menopausal syndrome in our hospital from 2015 to 2018, and compare the retention rate of estrog...
This study aimed to investigate the effects of tibolone,a synthetic steroid,on several metabolic dysfunctions induced by oestrogen deficiency,in rats.Ovariectomised(OVX)rats were used as animal model of postmenopausal...
supported by FIS/IMSS project No.FIS/IMSS/PROT/G09/751 and FIS/IMSS/PROT/G11-2/1013
Oxidative stress (OS) is a key process in the development of many neurodegenerative diseases, memory disorders, and other pathological processes related to aging. Tibolone (TIB), a synthetic hormone used as a trea...
Objective:To study the effect of self prescription for nourishing liver and kidney combined with tibolone on hormone levels, lipid metabolism and immune response in women with menopausal syndrome.Methods: Patients wit...
supported by FIS/IMSS project No.FIS/IMSS/PROT/G13/1216;CGA received Beca de Excelencia en Investigación by Fundación IMSS,ACS;JJSU received financial support from CIS/IMSS;CONACy T,RPA received financial support from USC-CONACYT Postdoctoral Scholars Program
Estrogen receptor modulators are compounds of interest because of their estrogenic agonistic/antagonistic effects and tissue specificity. These compounds have many clinical applications, particularly for breast cancer...
Objective: To explore the effect of tibolone as well as Estradiol and Drospirenone replacement therapy on the neurohumoral indexes and immune function in perimenopausal women. Methods: A total of 180 perimenopausal wo...
supported by FIS/IMSS project No.FIS/IMSS/PROT/G13/1216;COFAA;SIP-IPN;by DGAPA-UNAM IN203616
Aging is a key risk factor for cognitive decline and age-related neurodegenerative disorders. Also, an age-related decrease in sex steroid hormones may have a negative impact on the formation of neurofibrillary tangl...
Introduction: Premature Ovarian Failure (POF) is cessation of ovarian functions before the age of 40 years old with consequent cessation of menstruation. Objective of study: The aim of this study was to evaluate the a...
supported by the Sci-tech Research Development Program of Shaanxi Province (No.2015SF015)
The aim of this study was to evaluate the effects of low-dose tibolone therapy on ovarian area, uterine volume and endometrial thickness, and define the cut-off value of endometrial thickness for curettage during uter...
Background:As a Chinese Traditional Medicine product,Kuntai capsule could improve the peri-menopausal symptoms in postmenopausal women.But it is still not clear whether Kuntai capsule has a good effect on alleviating...