TIBOLONE

作品数:22被引量:60H指数:3
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相关领域:医药卫生更多>>
相关作者:李琴葛秦生廖秦平黄学惠程国钧更多>>
相关机构:北京大学新疆乌鲁木齐兵团医院中国医学科学院北京协和医学院北京大学第一医院更多>>
相关期刊:《Chinese Medical Journal》《中国骨质疏松杂志》《中国妇幼保健》《Journal of Hainan Medical University》更多>>
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Study on drug retention in menopausal women with sequential hormone therapy and tibolone被引量:1
《Journal of Chinese Pharmaceutical Sciences》2020年第9期649-655,共7页Shurong Shao Xiaoqing Shao Yi Chen 
Ningbo Public Welfare Science and Technology Plan(Grant No.2019C50089)。
In the present study, we aimed to retrospectively analyze the medication prescriptions of menopausal women diagnosed with menopausal syndrome in our hospital from 2015 to 2018, and compare the retention rate of estrog...
关键词:Hormone replacement therapy Menopausal syndrome Femoston TIBOLONE Drug retention rate 
Tibolone Reverses NAFLD in Ovariectomised Rats by Reducing Adiposity and Insulin Resistance
《Journal of Pharmacy and Pharmacology》2019年第4期148-164,共17页Lilian Brites Campos-Shimada Eduardo Hideo Gilglioni Danielle Aparecida Munhos Hermoso Ana Julia dos Reis Buzzo Rosangela Fernandes Garcia Elismari Rizato Martins-Maciel Emy Luiza Ishii-Iwamoto Clairce Luzia Salgueiro-Pagadigorria 
This study aimed to investigate the effects of tibolone,a synthetic steroid,on several metabolic dysfunctions induced by oestrogen deficiency,in rats.Ovariectomised(OVX)rats were used as animal model of postmenopausal...
关键词:TIBOLONE OVARIECTOMY hepatic STEATOSIS obesity OXIDATIVESTRESS 
Effect of tibolone pretreatment on kinases and phosphatases that regulate the expression and phosphorylation of Tau in the hippocampus of rats exposed to ozone
《Neural Regeneration Research》2018年第3期440-448,共9页Rodolfo Pinto-Almazán Julia J. Segura-Uribe Marvin A. Soriano-Ursúa Eunice D. Farfán-García Juan M. Gallardo Christian Guerra-Araiza 
supported by FIS/IMSS project No.FIS/IMSS/PROT/G09/751 and FIS/IMSS/PROT/G11-2/1013
Oxidative stress (OS) is a key process in the development of many neurodegenerative diseases, memory disorders, and other pathological processes related to aging. Tibolone (TIB), a synthetic hormone used as a trea...
关键词:TIBOLONE oxidative stress ozone exposure TAU GSK3 HIPPOCAMPUS neuroprotection 
Effect of self prescription for nourishing liver and kidney combined with tibolone on hormone levels, lipid metabolism and immune response in women with menopausal syndrome
《Journal of Hainan Medical University》2017年第17期79-82,共4页Ming-Xi Zhu Yu-Ling Chen 
Objective:To study the effect of self prescription for nourishing liver and kidney combined with tibolone on hormone levels, lipid metabolism and immune response in women with menopausal syndrome.Methods: Patients wit...
关键词:MENOPAUSAL syndrome HORMONE replacement LIPID metabolism Immune response 
Effects of estrogen receptor modulators on cytoskeletal proteins in the central nervous system被引量:2
《Neural Regeneration Research》2017年第8期1231-1240,共10页Julia J.Segura-Uribe Rodolfo Pinto-Almazán Angélica Coyoy-Salgado Claudia E.Fuentes-Venado Christian Guerra-Araiza 
supported by FIS/IMSS project No.FIS/IMSS/PROT/G13/1216;CGA received Beca de Excelencia en Investigación by Fundación IMSS,ACS;JJSU received financial support from CIS/IMSS;CONACy T,RPA received financial support from USC-CONACYT Postdoctoral Scholars Program
Estrogen receptor modulators are compounds of interest because of their estrogenic agonistic/antagonistic effects and tissue specificity. These compounds have many clinical applications, particularly for breast cancer...
关键词:estrogen receptor modulators selective estrogen receptor modulators MICROTUBULES NEUROFILAMENTS TIBOLONE TAMOXIFEN RALOXIFENE 
Effect of tibolone as well as Estradiol and Drospirenone replacement therapy on the neurohumoral indexes and immune function in perimenopausal women
《Journal of Hainan Medical University》2017年第15期104-107,共4页Ling-Ge Jin Jing Jin 
Objective: To explore the effect of tibolone as well as Estradiol and Drospirenone replacement therapy on the neurohumoral indexes and immune function in perimenopausal women. Methods: A total of 180 perimenopausal wo...
关键词:PERIMENOPAUSE TIBOLONE ESTRADIOL and DROSPIRENONE Neurohumoral indexes Immune function 
Tibolone modulates neuronal plasticity through regulating Tau, GSK3β/Akt/PI3K pathway and CDK5 p35/p25 complexes in the hippocampus of aged male mice被引量:12
《Neural Regeneration Research》2017年第4期588-595,共8页Teresa Neri-Gomez Judith Espinosa-Raya Sofia Diaz Cintra Julia Segura-Uribe Sandra Orozco-Suarez Juan Manuel Gallardo Christian Guerra-Araiza 
supported by FIS/IMSS project No.FIS/IMSS/PROT/G13/1216;COFAA;SIP-IPN;by DGAPA-UNAM IN203616
Aging is a key risk factor for cognitive decline and age-related neurodegenerative disorders. Also, an age-related decrease in sex steroid hormones may have a negative impact on the formation of neurofibrillary tangl...
关键词:nerve regeneration TIBOLONE HIPPOCAMPUS aged mice sex steroids AKT GSK3Β PI3K neuralplasticity TAU neurofibrillary tangles neural regeneration 
Beneficial Effects of Tibolone on Sexual Dys-function in Women with Premature Ovarian Failure (POF)
《Health》2016年第9期857-867,共11页Florence E. Omu Assem Elbiaa Amal Ghafour Ibrahim Gadalla Alexander E. Omu 
Introduction: Premature Ovarian Failure (POF) is cessation of ovarian functions before the age of 40 years old with consequent cessation of menstruation. Objective of study: The aim of this study was to evaluate the a...
关键词:Premature Ovarian Failure Sexual Dysfunction TIBOLONE Replacement Therapy 
Dynamic monitoring of menopause hormone therapy and defining the cut-off value of endometrial thickness during uterine bleeding被引量:3
《The Journal of Biomedical Research》2016年第3期191-196,共6页Qiu Sheng Jun Yang Qiaoling Zhao Fen Li 
supported by the Sci-tech Research Development Program of Shaanxi Province (No.2015SF015)
The aim of this study was to evaluate the effects of low-dose tibolone therapy on ovarian area, uterine volume and endometrial thickness, and define the cut-off value of endometrial thickness for curettage during uter...
关键词:low-dose tibolone ovarian area uterine volume ENDOMETRIUM dynamic monitoring cut-off value 
Efficacy and Safety Investigation of Kuntai Capsule for the Add-back Therapy of Gonadotropin Releasing Hormone Agonist Administration to Endometriosis Patients: A Randomized,Double-blind, Blank-and Tibolone-controlled Study被引量:31
《Chinese Medical Journal》2015年第4期427-432,共6页Ji-Ming Chen Hong-Yan Gao Yi Ding Xia Yuan Qing Wang Qin Li Guo-Hua Jiang 
Background:As a Chinese Traditional Medicine product,Kuntai capsule could improve the peri-menopausal symptoms in postmenopausal women.But it is still not clear whether Kuntai capsule has a good effect on alleviating...
关键词:ENDOMETRIOSIS Kuntai Capsule Kupperman Menopausal Index Peri-menopausal Symptoms TIBOLONE 
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