PROTOPORPHYRIN

作品数：21被引量：32H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：梁荣能陈暨耀麦乃歧熊建文黄康强更多>>
相关机构：复旦大学香港浸会大学东南大学中国移动通信集团广东有限公司更多>>
相关期刊：《Plant Communications》《Journal of Clinical and Nursing Research》《Open Journal of Animal Sciences》《Journal of Cancer Therapy》更多>>
相关基金：国家自然科学基金泰国研究基金中国博士后科学基金江苏省自然科学基金更多>>
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Research Progress on Serum Porphyrin and Chronic Liver Disease
《Journal of Clinical and Nursing Research》2022年第3期221-228,共8页Xia Wang Yu Cai Weiqin Li Yuanyuan Jia Jiangfeng Fu Yaping Ni Kaige Liu 
This study was supported by Key Research and Development Project of Shaanxi Science and Technology Department in 2022(Project No.:2022SF-577):Research on Correlation between Porphyrin and Chronic Liver Disease.
Liver cirrhosis is an important cause of chronic liver cancer.At present,a breakthrough has been achieved in the development of chronic hepatitis C treatment,but there is no effective measure to completely cure chroni...
关键词：Viral hepatitis Chronic hepatitis B HEMOGLOBIN PROTOPORPHYRIN PORPHYRIN 
ProtoporphyrinⅨand verteporfin potently inhibit SARS-CoV-2 infection in vitro and in a mouse model expressing human ACE2
《Science Bulletin》2021年第9期925-936,M0004,共13页Chenjian Gu Yang Wu Huimin Guo Yuanfei Zhu Wei Xu Yuyan Wang Yu Zhou Zhiping Sun Xia Cai Yutang Li Jing Liu Zhong Huang Zhenghong Yuan Rong Zhang Qiang Deng Di Qu Youhua Xie 
supported by the National Science and Technology Major Project(NSTMP)for the Prevention and Treatment of Infectious Diseases(2018ZX10734401,2018ZX10301208);the NSTMP for the Development of Novel Drugs(2019ZX09721001);the Project of Novel Coronavirus Research of Fudan University,China Postdoctoral Science Foundation(2020T130016ZX)。
The SARS-CoV-2 infection is spreading rapidly worldwide.Efficacious antiviral therapeutics against SARSCo V-2 is urgently needed.Here,we discovered that protoporphyrin IX(Pp IX)and verteporfin,two Food and Drug Admini...
关键词：SARS-CoV-2 ACE2 ProtoporphyrinⅨ VERTEPORFIN 
A Thylakoid Membrane Protein Functions Synergistically with GUN5 in Chlorophyll Biosynthesis被引量：2
《Plant Communications》2020年第5期100-110,共11页Chi Zhang Bin Zhang Baicong Mu Xiaojiang Zheng Fugeng Zhao Wenzhi Lan Aigen Fu Sheng Luan 
supported by the National Natural Science Foundation of China(grant no.31900220 to C.Z.,and 31770267 to W.L.);the National Science Foundation(MCB-1714795 to S.L.).
Chlorophyll(Chl)is essential for photosynthetic reactions and chloroplast development.While the enzymatic pathway for Chl biosynthesis is well established,the regulatory mechanism underlying the homeostasis of Chl lev...
关键词：chlorophyll biosynthesis MAGNESIUM thylakoid membrane GUN5 magnesium protoporphyrin 
Letter to the editor: Diagnosis of erythropoietic protoporphyria with severe liver injury-a case report被引量：2
《World Journal of Gastroenterology》2019年第30期4292-4293,共2页Debby Wensink Margreet AEM Wagenmakers JH Paul Wilson Janneke G Langendonk 
Erythropoietic protoporphyria(EPP)is an extremely rare disease which is often unrecognized as diagnosis.In the recent article Lui et al describe a patient with a new diagnosis of EPP with severe liver injury.Approxima...
关键词：Erythropoietic protoporphyria LIVER DISEASE BLOOD TRANSFUSION PROTOPORPHYRIN IX Treatment 
Calcium Participates in Secretion of Porphyrin from Shell Gland Epithelial Cells of Japanese Quail (<i>Coturnix coturnix japonica</i>)
《Open Journal of Animal Sciences》2019年第1期151-161,共11页Osamu Kai 
To investigate factors involved in the secretion of protoporphyrin IX (PpIX), a superficial eggshell pigment, from shell gland epithelial cells of Japanese quail, we cultured cells in Ham’s F12 medium with calcium ch...
关键词：Japanese Quail SHELL GLAND Epithelial Cells In Vitro Culture CALCIUM Chloride PROTOPORPHYRIN 
The role of heme-oxygenase-1 in pathogenesis of cerebral malaria in the co-culture model of human brain microvascular endothelial cell and ITG Plasmodium falciparum-infected red blood cells
《Asian Pacific Journal of Tropical Medicine》2017年第1期20-24,共5页Pimwan Thongdee Kesara Na-Bangchang 
supported by The Commission on Higher Education,Ministry of Education of Thailand,The National Research University Project of Thailand(NRU);Office of Higher Education Commission,Thammasat University(Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma);Liverpool School of Tropical Medicine,University of Liverpool,UK;The Royal Golden Jubilee PhD Programme,Thailand Research Fund-Thammasat University Joint Fund and Graduated Student Grant to P.Thongdee(Grant No.PHD/0365/2552)
Objective: To investigate the role of human host heme-oxygenase-1(HO-1) in pathogenesis of cerebral malaria in the in vitro model,Methods: The effect of human host HO-1 [human brain microvascular endothelial cell(HBME...
关键词：Plasmodium falciparum Heme-oxygenase-1 Zn(Ⅱ)-protoporphyrin Ⅸ inhibitor Co-protoporphyrin Ⅸ inducer Human brain microvascular endothelial cell 
Recent advances in photodynamic diagnosis of gastriccancer using 5-aminolevulinic acid被引量：7
《World Journal of Gastroenterology》2016年第3期1289-1296,共8页Noriaki Koizumi Yoshinori Harada Takeo Minamikawa Hideo Tanaka Eigo Otsuji Tetsuro Takamatsu 
Photodynamic diagnosis based on 5-aminolevulinic acidinduced protoporphyrin IX has been clinically applied in many fields based upon its evidenced efficacy and adequate safety. In order to establish a personalized med...
关键词：Gastric cancer Photodynamic diagnosis 5-aminolevulinic acid PROTOPORPHYRIN IX LYMPH nodemetastasis PERSONALIZED medicine PERITONEAL DISSEMINATION 
Preliminary study of photodynamic diagnosis using 5-aminolevulinic acid in gastric and colorectal tumors
《World Journal of Gastroenterology》2015年第21期6706-6712,共7页Munetaka Nakamura Jun Nishikawa Kouichi Hamabe Atsushi Goto Junichi Nishimura Hiroaki Shibata Misato Nagao Sho Sasaki Shinichi Hashimoto Takeshi Okamoto Isao Sakaida 
AIM:To investigate the utility of photodynamic diagnosis(PDD) using 5-aminolevulinic acid(5-ALA) to detect gastric/colorectal tumors.METHODS:This prospective single-center study investigated inter-subject variability ...
关键词：Photodynamic DIAGNOSIS 5-aminolevulinicacid PROTOPORPHYRIN IX  GASTRIC TUMOR Colorectaltumor 
Induced Deactivation of Genes Encoding Chlorophyll Biosynthesis Enzymes Disentangles Tetrapyrrole- Mediated Retrograde Signaling被引量：3
《Molecular Plant》2014年第7期1211-1227,共17页Hagen Schlicke Annabel Salinas Hartwig Vivien Firtzlaff Andreas S. Richter , Christine Glasser Klaus Maier Iris Finkemeier Bernhard Grimm 
In photosynthetic organisms, tetrapyrrole-mediated retrograde signals are proposed to contribute to a bal- anced nuclear gene expression （NGE） in response to metabolic activity in chloroplasts. We followed an experi...
关键词：plastid signal transcription analysis retrograde signal tetrapyrrole metabolism Mg protoporphyrin. 
Action of protoporphyrin-IX (PP-IX) in the lifespan of <i>Drosophila melanogaster</i>deficient in endogenous antioxidants, Sod and Cat
《Open Journal of Animal Sciences》2013年第4期1-7,共7页Emilio Pimentel Luz M. Vidal Martha Patricia Cruces Mariusz Krzysztof Janczur 
Protoporphyirin-IX (PP-IX) is a precursor of the biosynthesis of the hemo group, most of the cytochromes and the chlorophylls. The PP-IX is used for medical purposes, and recently a report indicated that it exhibits a...
关键词：PROTOPORPHYRIN IX (PP-IX) LIFESPAN SOD CAT Reactive Oxygen Species Longevity Drosophila melanogaster 
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