partially supported by the National Key Research and Development Program of China(2021YFD1300201);Jilin Province Key Research and Development Program of China(20220202044NC)。
Background Promoting the synchronization of glucose and amino acid release in the digestive tract of pigs could effectively improve dietary nitrogen utilization.The rational allocation of dietary starch sources and th...
supported by grants from the National Natural Science Foundation of China(82170818,81770794);Guangdong Basic and Applied Basic Research Foundation(2024A1515010686,China);the Fundamental Research Funds for the Central Universities(21620423,China).
Obesity is primarily caused by excessive intake as well as absorption of sugar and lipid.Postprandial surge in distention pressure and intestinal motility accelerates the absorption of nutrients.The response of intest...
funded by the National Natural Science Foundation of China(31672433,31560640),China;Special fund for scientific innovation strategy-construction of high level Academy of Agriculture Science-the Outstanding Talents Training Program of Guangdong Academy of Agricultural Sciences(R2018PY-JC001),China;Special fund for scientific innovation strategy-construction of high level Academy Of Agriculture Science-The Talents Training Program Of Guangdong Academy Of Agricultural Sciences-Young Associate Researcher(R2018PY-QF001),China.
As major fuels for the small intestinal mucosa,dietary amino acids(AA)are catabolized in the mitochondria and serve as sources of energy production.The present study was conducted to investigate AA metabolism that sup...
supported by Key Programs of Frontier Scientific Research of the Chinese Academy of Sciences(QYZDYSSW-SMC008);Natural Science Foundation of Hunan Province(2017JJ1020);Young Elite Scientists Sponsorship Program by CAST(YESS20160086)。
Epidermal growth factor(EGF) has been shown to improve piglet intestinal morphology and epithelial recovery. In an attempt to further understand the mechanisms behind these improvements, this study tested the hypothes...
supported by National Natural Science Foundation of China(No.31772620);China Agricultural Research System Poultry-related Science and Technology Innovation Team of Peking(BAIC 04-2018)
Background: There is growing interest in carbohydrate and protein nutrition to enhance the efficiency of animal production.Reduced-crude protein diets depress environmental pollution and feeding cost,but the challenge...
Supported by The National Natural Science Foundation of China,No.81300291
AIMTo examine the role of A20 in the regulation of intestinal epithelial cells (IECs) inflammation. METHODSUsing gene transfection, both stable overexpression and knockdown A20-expressed HT-29 cell lines were establis...
Supported by Deutsche Forschungsgemeinschaft,No.DFG GA 785/5-1(partially);Deutsche Krebshilfe,No.GA 109313(partially)
AIM: To verify the hypothesis that caspase-8(Casp8), which regulates cellular apoptosis and necroptosis, is critically involved in enterocyte migration.METHODS: Casp8-silenced Caco2 cells were used in migration assays...
Supported by National Science Council, No. NSC99-2628-B-002-008-MY3 and NSC100-2325-B-002-035
The gastrointestinal tract is the largest reservoir of commensal bacteria in the human body, providing nutrients and space for the survival of microbes while concurrently operating mucosal barriers to confine the mic...
Tight junctions(TJs)are structures between cells where cells appear in the closest possible contact.They are responsible for sealing compartments when epithelial sheets are generated.They regulate the permeability of ...
supported by Program for Changjiang Scholars and Innovative Reseach Team in University (IRTO 555);Applied Basic Research(045Y029-031) of Sichuan Province,People's Republic of China
The experiment was conducted to study the effects and possible mechanism of GLP-2 on proliferation,metabolism and apoptosis of cultured enterocytes from a 28-d weaned piglet injured by exposure to β-conglycinin.A cel...