MYCOBACTERIAL

作品数:28被引量:40H指数:4
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相关领域:医药卫生更多>>
相关作者:林昊吴勇丁辉章晓联更多>>
相关机构:北京大学教育部武汉大学更多>>
相关期刊:《Cellular & Molecular Immunology》《Science China(Life Sciences)》《World Journal of Gastroenterology》《Open Journal of Respiratory Diseases》更多>>
相关基金:国家自然科学基金北京市自然科学基金重庆市自然科学基金瑞士科学基金更多>>
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Ocular tuberculosis associated with Epstein-Barr virus myelitis: A case report
《Infectious Medicine》2024年第3期73-77,共5页Fakhri Alahyari Raheleh Halabian Javad Hosseini Nejad 
Ocular tuberculosis(OTB)is a chronic eye infection caused by Mycobacterium tuberculosis.Some cases of myelitis are associated with Epstein-Barr virus(EBV),with 1-5%of EBV infections leading to neurologic complications...
关键词:EPSTEIN-BARR virus MYCOBACTERIAL infection MYELITIS OCULAR TUBERCULOSIS 
Inhibiting the oligomerization of mycobacterial DNA-directed RNA polymerase(RNAP)using natural compound via in-silico techniques
《Medicine in Novel Technology and Devices》2024年第1期97-109,共13页Ehssan H.Moglad 
We appreciate Prince Sattam bin Abdulaziz University for funding this project(PSAU/2023/R/1444).
Mycobacterium tuberculosis(Mtb)is responsible for the spread of tuberculosis(TB).The current study employed virtual screening of 2569 natural compounds against the DNA-directed RNA polymerase(RNAP)of Mtb to identify t...
关键词:Mycobacterium tuberculosis DNA-Directed RNA polymerase DOCKING Steered MD simulation Natural compounds Binding free energy Umbrella sampling 
A Systematic Review on Antituberculosis Drug Discovery and Antimycobacterial Potential of Biologically Synthesized Silver Nanoparticles:Overview and Future Perspectives
《Infectious Microbes & Diseases》2022年第4期139-148,共10页Christian K.Ezeh Chibuzor N.Eze Uju M.E.Dibua Stephen C.Emencheta 
Rapid emergence and quick evolution of drug-resistant and aggressive mycobacterial strains have resulted in the present antimycobacterial drug crisis and the persistence of tuberculosis as a major public health proble...
关键词:antimycobacterial activity silver nanoparticles CYTOTOXICITY biological synthesis TUBERCULOSIS MYCOBACTERIAL 
Lnc-EST12,which is negatively regulated by mycobacterial EST12,suppresses antimycobacterial innate immunity through its interaction with FUBP3被引量:4
《Cellular & Molecular Immunology》2022年第8期883-897,共15页Qili Yao Yan Xie Dandan Xu Zilu Qu Jian Wu Yuanyuan Zhou Yuying Wei Huan Xiong Xiao-Lian Zhang 
the Animal Biosafety Level 3 Laboratory(ABSL-III)of the Wuhan University School of Medicine(NO.18021B);the Second Military Medical University of Shanghai(No.18002)for their help with the M.tb infection experiment;This project was supported by grants from the National Grand Program on Key Infectious Disease of China(2017ZX10201301-006 and 2012ZX10003002-015);the National Key R&D Program of China(2018YFA0507603);the National Natural Science Foundation of China(91740120,22077097 and 21721005);the National Outstanding Youth Foundation of China(81025008);Hubei Province’s Outstanding Medical Academic Leader Program(523-276003);Hubei Province Key R&D Program(2020BCB020);Research and Innovation Team Project of Hubei Provincial Health Commission(WJ2021C002);the Medical Science Advancement Program(Basic Medical Sciences)of Wuhan University(TFJC 2018002);the Fundamental Research Funds for the Central Universities.
Long noncoding RNAs (lncRNAs) have been implicated in the pathogenesis of intracellular pathogens. However, the role andmechanism of the important lncRNAs in Mycobacterium tuberculosis (M.tb) infection remain largely ...
关键词:Mycobacterium tuberculosis lncRNA PYROPTOSIS CYTOKINES 
Assessment of the Quality of Life of Patients with Mycobacterial Pulmonary Diseases
《Open Journal of Respiratory Diseases》2022年第2期56-63,共8页Khadidia Ouattara Bocar Baya Dianguina Soumaré Tenin Kanouté Mohamed Tolofodie Kafui Komla Gaglo Koudemon Salif Koné Bassirou Diarra Yaya Sadio Sarro Yacouba Toloba Mamoudou Maiga 
Introduction: Mycobacteria pulmonary diseases are chronic illnesses with various impacts on patients’ health status, and wellbeing. These diseases currently represent a global health issue due to increasing burdens a...
关键词:Quality of Life MYCOBACTERIA LUNG 
GP30 of the mycobacteriophage CASbig impairs mycobacterial adaptation during acidic stress and in macrophages
《BIOCELL》2020年第4期695-701,共7页WU LI JIANGZHE SI SHUAI QIU JING LUO HUIQIONG SUN XIAOQING LI ZHIBIN WAN WEI GAO HANLU ZOU LEI ZHANG XIAOHONG XIANG YANZHANG LI TIESHAN TENG 
Key R&D and Promotion Projects of Henan Province,grant number 192102310156,the National Natural Science Foundation of China,Grant No.81601740;the Applied Basic Research Program of Science&Technology Department of Sichuan Province,Grant No.2018JY0108;the National Undergraduate Training Program for Innovation and Entrepreneurship(X2017013,X2019070,202010475006).
The rapid emergence of multidrug-resistant and extensively drug-resistant Tuberculosis retrieved intense interest in phage-based therapy.This old approach,which was abandoned in the west in the 1940s but is generating...
关键词:MYCOBACTERIUM SMEGMATIS gp30 CASbig ACIDIC STRESS Macrophage 
Crohn’s strictures open with anti-mycobacterial antibiotic therapy:A retrospective review
《World Journal of Gastrointestinal Endoscopy》2020年第12期542-554,共13页Rhys Collyer Annabel Clancy Gaurav Agrawal Thomas J Borody 
BACKGROUND Medical therapy for strictures is limited and first-line treatment consists of endoscopic balloon dilatation,strictureplasty or surgical resection.Mycobacterium tuberculosis,Helicobacter pylori and Streptoc...
关键词:ANTIBIOTICS COLONOSCOPY Crohn’s disease ILEUM Inflammatory bowel disease STRICTURE 
Molecular Epidemiology of <i>Mycobacterium tuberculosis</i>among Pulmonary Tuberculosis Patients in Ilorin, Nigeria
《Health》2020年第7期840-848,共9页O. A. Olalubi P. O. Omosigho A. O. Sodipe A. I. Lukman 
Background: Tuberculosis (TB) is an infectious disease and it is a public health concern due to the endemic nature of the disease. Nigeria’s health systems still rely heavily on out-dated tuberculosi...
关键词:Mycobacterial tuberculosis Gene Expert EPIDEMIOLOGY Care Outcomes Pulmonary Tuberculosis 
Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2
《Protein & Cell》2020年第7期505-517,共13页Lu Zhang Yao Zha Ruogu Gao Jun Li Xiuna Yang Yan Gao Wei Zhao Sudagar S.Gurcha Natacha Veerapen Sarah M.Batt Kajelle Kaur Besra Wenqing Xu Lijun Bi Xian'en Zhang Luke W.Guddat Haitao Yang Quan Wang Gurdyal S.Besra Zihe Rao 
Inhibition of Mycobacterium tuberculosis(Mtb)cell wall assembly is an established strategy for anti-TB chemotherapy.Arabinosyltransferase EmbB,which catalyzes the transfer of arabinose from the donor decaprenyl-phosph...
关键词:Mycobacterium tuberculosis EmbB CRYO-EM ETHAMBUTOL cell wall synthesis arabinoglacatan arabinosyltransferase acyl-carrier-protein drug discovery 
Benzofuran-isatin-hydroxylimine/thiosemicarbazide hybrids:Design,synthesis and in vitro anti-mycobacterial activity evaluation被引量:2
《Chinese Chemical Letters》2019年第3期653-655,共3页Yaohuan Zhang Ruo Wang Tesen Zhang Weitao Yan Yihong Chen Yanping Zhang Muyang Zhou 
A series of novel benzofuran-isatin-hydroxylimine/thiosemicarbazide hybrids were designed, synthesized and evaluated for their in vitro anti-TB activities against drug-sensitive MTB H_(37)Rv and MDR-TB isolates as wel...
关键词:BENZOFURAN ISATIN Hybrid compounds Anti-mycobacterial Anti-tubercular Multi-drug resistant STRUCTURE-ACTIVITY relationship 
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