云南高校图书馆联盟文献共享服务平台- ENKEPHALIN

ENKEPHALIN: 作品数：29被引量：67H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李晓玉姚丹郭岑陈生弟饶志仁更多>>; 相关机构：中国科学院中国药科大学第四军医大学长崎大学更多>>; 相关期刊：《Neural Regeneration Research》《中国医学科学院学报》《World Journal of Acupuncture-Moxibustion》《中国现代应用药学》更多>>; 相关基金：国家自然科学基金更多>>

Conformation Changes of Enkephalin in Coordination with Pb^(2+) Investigated by Gas Phase Hydrogen/Deuterium Exchange Mass Spectrometry Combined with Theoretical Calculations: 《Chemical Research in Chinese Universities》2022年第2期572-578,共7页HAN Jiaru WU Fangling YANG Shutong WU Xiaonan TANG Keqi LI Zhenhua DING Chuan-Fan; supported by the National Natural Science Foundation of China (Nos.22004074,21927805,21803013 and 21773035);the Public Welfare Fund Project of Ningbo City,China(No.202002N3113);the National Key Research and Development Program of China(No.2020YFF01014601);the K.C.Wong Magna Fund in Ningbo University,China.; In this study, the effects of lead ions(Pb^(2+)) on the conformations of leucine encephalin(LE) and methionine encephalin(ME) in gas phase were studied using hydrogen/deuterium exchange mass spectrometry(HDX-MS) and q...; 关键词：Encephalin Pb^(2+) Gas phase-hydrogen/deuterium exchange(HDX) Theoretical calculation ESI-TOF-MS

d-Penicillamine2,5-enkephalin作为底物考察三明治大鼠原代肝细胞的转运体功能研究: 《中国临床药理学与治疗学》2013年第5期506-512,共7页郭岑赫蕾姚丹潘国宇王广基; 国家自然科学基金项目(81173116);江苏省药代动力学重点实验室提升项目(BM20120102); 目的:通过液相色谱-串联质谱(LC/MS/MS)法测定d-Penicillamine2,5-enkephalin(DP-DPE)在肝细胞和Hank's缓冲液中的浓度,研究DPDPE作为底物用于"三明治"培养大鼠原代肝细胞(SCRH)的转运体功能。方法:将SCRH与溶于Hank's缓冲液的DPDPE共温...; 关键词：转运体 “三明治”培养大鼠原代肝细胞 LC MS MS DPDPE

Midbrain enkephalin expression in a rat migraine model following intragastric scorpion powder administration被引量：10: 《Neural Regeneration Research》2011年第12期903-907,共5页Gang Yao Xiangdan Luo Dihui Ma Tingmin Yu; Scorpion has strong analgesic effects, but its analgesic mechanisms remain unclear. This study investigated the effects of scorpion powder on enkephalin expression in the midbrain of rats with nitroglycerin-induced mi...; 关键词：PROENKEPHALIN METHIONINE-ENKEPHALIN LEUCINE-ENKEPHALIN MIGRAINE SCORPION rats

Effects of Toutongning capsule on enkephalin expression in a rat migraine headache model被引量：7: 《Neural Regeneration Research》2011年第9期661-665,共5页Gang Yao Yuhong Man Jingjing Qi Tingmin Yu Dihui Ma; Toutongning capsule is used for the treatment of migraine headaches, and has yielded therapeutically beneficial effects. However, whether Toutongning capsule exerts its effects via endogenous opioid peptides remains p...; 关键词：PROENKEPHALIN METHIONINE-ENKEPHALIN LEUCINE-ENKEPHALIN migraine headache Toutongning capsule neural regeneration

Overexpression of OGFr Downregulates Ovarian Cancer Cell Proliferation <i>In Vitro</i>and Inhibits Tumorigenesis: 《Journal of Cancer Therapy》2011年第4期579-594,共16页Renee N. Donahue Patricia J. McLaughlin Ian S. Zagon; The opioid growth factor (OGF) and its receptor (OGFr) regulate human ovarian cancer cell proliferation through a tonically active inhibitory axis. We investigated the effect of OGFr overexpression on ovarian tumorige...; 关键词：Cell Proliferation OPIOIDS [Met5]-Enkephalin OGF OGFr OVARIAN Cancer

The Opioid Growth Factor Inhibits Established Ovarian Cancer in Nude Mice and Can Be Combined with Taxol or Cisplatin to Enhance Growth Inhibition被引量：1: 《Journal of Cancer Therapy》2011年第2期110-124,共15页Renee N. Donahue Ian S. Zagon Patricia J. McLaughlin; Ovarian cancer is the 5th leading cause of cancer-related mortality in women. Seventy-five percent of ovarian cancer patients present in advanced stages, and receive cytoreductive surgery and adjuvant chemotherapy. Ho...; 关键词：Cell Proliferation [Met5]-Enkephalin OPIOID Growth Factor OGFr OVARIAN Cancer

Endogenous enkephalin does not contribute to the cerebral anti-hyperalgesic action of gabapentin被引量：5: 《Science China(Life Sciences)》2010年第12期1428-1432,共5页CHEN ShaoHui ZHAO Jing HUANG YuGuang LUO AiLun ZUO PingPing YANG Nan HAO WenYu; The aim of this study was to investigate the role of endogenous enkephalin in the cerebral antihyperalgesic action of gabapentin.Neuropathic pain models and antihyperalgesic effect of gabapentin were confirmed by the ...; 关键词：neuropathic pain GABAPENTIN ENKEPHALIN cerebral cortex

Construction and identification of immortalized rat astrocyte cell line expressing enkephalin: 《Chinese Journal of Traumatology》2007年第6期353-356,共4页徐颖田玉科田学愎安珂场辉; the National Natural Science Foundation of China(No.30170905)and Paul Janssen Foundation.; Objective:To provide a sound cell source for further ex-vivo gene therapy for chronic pain,we attempt to develop an immortalized rat astrocyte cell line that expresses enkephalin regulated by doxycycline. Methods:Retr...; 关键词：ENKEPHALINS Gene therapy ASTROCYTES Spinal cord injuries

Involvement of δ-and μ-opioid receptors in the delayed cerebral ischemic tolerance induced by repeated electroacupuncture preconditioning in rats被引量：21: 《Chinese Medical Journal》2007年第5期394-399,共6页XIONG Li-ze YANG Jing WANG Qiang LU Zhi-hong; the National Natural Science Foundation of China(No.30471664).; Background Preconditioning with repeated electroacupuncture （EA） could mimic ischemic preconditioning to induce cerebral ischemic tolerance in rats. The present study was designed to investigate whether mu（μ）-, d...; 关键词：ELECTROACUPUNCTURE PRECONDITIONING ischemic tolerance opioid receptor ENKEPHALIN

Changes of mRNA expression of enkephalin and prodynorphin in hippocampus of rats with chronic immobilization stress被引量：6: 《World Journal of Gastroenterology》2004年第17期2547-2549,共3页Jia-XuChen WeiLi XinZhao Jian-XinYang Hong-YanXu Zhu-FengWang Guang-XinYue; Supported by the National Natural Science Foundation of China,No.30000216,Teaching and Research Award Program for Outstanding Young Teachers in Higher Education Institutes of Ministry of Education,China,Foundation for the Authors of National Excelle; AIM: To observe the changes of enkephalin mRNA and prodynorphin mRNA in hippocampus of rats induced by chronic immobilization stress.METHODS: Thirty rats were randomly divided into three groups of 10 each: the normal ...; 关键词：mRNA表达脑啡肽海马神经老鼠慢性压力作用基因表达正强啡肽

ENKEPHALIN