Supported by grants from NIH in part,Philip Morris United States,and The Pennsylvania Department of Heath,as well as generous gifts from the Paul I and Anna E Shockey Family Foundation
Opioid growth factor (OGF), chemically termed [Met5]-enkephalin, and its receptor, OGF receptor (OGFr), form a biological axis that tonically regulates cell proliferation by delaying the G1/S int...
supported by the National Basic Research Program of China (973 Program) (No. 2009CB522900);the National Natural Science Foundation of China (No. 30973783);the Shanghai Leading Academic Discipline Project (No. S30304)
Rats that modeled chronic visceral hyperalgesia received suspended moxibustion at bilateral Tianshu (ST25) and Shangjuxu (ST37) once daily over a period of 7 days. Results show that suspended moxibustion significa...
supported by the National Basic Research Program of China(Nos.2007CB512501,2009CB522003).
Drug addiction is a chronic brain disorder characterized by withdrawal symptoms that occur during drug abstinence and a high tendency of relapse.Compared with the currently available pharmacological interventions,acup...
the National Natural Science Foundation of China(No.30170905)and Paul Janssen Foundation.
Objective:To provide a sound cell source for further ex-vivo gene therapy for chronic pain,we attempt to develop an immortalized rat astrocyte cell line that expresses enkephalin regulated by doxycycline. Methods:Retr...
AIM: To study the effects and mechanisms of melatonin (MT) on immune responses in mice of different months. METHODS: Thymocyte proliferation and IL-2 activity were assayed by 3-(4,5-dimethylthiazol-2-yl) 2,5diphenylte...
Project supported by the National Natural Science Foundation of China, № 39670829; Key Laboratory of Neuroscience, Shanghai Institute of Physiology, Chinese Academy of Sciences.
AIM:To study that l-stepholidine(SPD) regulates the expression of proenkephalin (PENK) and prodynorphin (PDYN) mRNA and Fos in the striatum after rotational test in the 6-hydroxydopamine (6-OHDA)-lesioned rats. METHOD...
This work was supported by the National fund of Natural Science.
In this experiment,we have observed the effects of acupuncture on the contents ofenkephalins in different brain regions and corticosterone in plasma of rats with endotoxin shock.Theresults showed that after acupunctur...
There is a growing body of evidence showing that periaqueductal gray (PAG) and nucleus accumbens (N. accumbens) play important roles in the modulation of nociception. In our previous study of the mechanisms of morphin...
After 20min electric field stimulation,L-enkephalin (L-ENK) content in the rabbitear artery declined from the control value of 38.99±17.29 to 12.55±1.96pg/mg of wet tissue(n=12),and M-enkephalin (M-ENK) conten...
The basic level of methionin-enkephalin(MEK)in rat medulla oblongata plus pons was the highestat 05:00 o’clock and the lowest at 23:00.In bothhypothalamus and striatum at 05:00 it was higherthan at 11:00,17:00 and 23...