Over the last years it has started a real revolution in the treatment of chronic hepatitis C. This occurred for the availability of direct-acting antiviral agents that allow to reach sustained virologic response in ap...
Metformin, a biguanide derivative, is the most commonly prescribed medication in the treatment of type 2 diabetes mellitus. More recently, the use of metformin has shown potential as a preventive and therapeutic agent...
Chronic hepatitis C infection is the leading cause of chronic liver disease, cirrhosis, hepatocellular carcinoma as well as the primary indication for liver transplantation in the United States. Despite recent advance...
A substantial proportion of individuals with chronic hepatitis C virus(HCV) are co-infected with human immunodeficiency virus(HIV). Co-infected individuals are traditionally considered as one of the "special populatio...
The Federal funds for the National Reference Centre for Hepatitis C,Herzer K has received grant support from Astellas,Biotest and Novartis and been a consultant/speaker for Abb Vie,Biotest,Bristol-Myers Squibb,Gilead Sciences,Janssen Pharmaceuticals,Novartis,and Roche;Gerken G has been a consultant/speaker for Abb Vie,Bristol-Myers Squibb,Gilead Sciences,Janssen Pharmaceuticals and Roche
AIM: To characterize management of telaprevir(TVR)-based triple therapy of hepatitis C virus(HCV) reinfection after liver transplantation(LT).METHODS: We retrospectively analyzed safety and efficacy of telaprevir- bas...
Supported by National Natural Science Foundation of China,No.30970415
AIM To investigate the utility of 1H magneticresonance spectroscopy (1H MRS) as a noninvasivetest for steatosis in patients infected with hepatitis Cvirus.METHODS: Ninety patients with chronic hepatitisC and pathol...
Liver diseases are an increasingly common cause of morbidity and mortality; new approaches for investigation of mechanisms of liver diseases and identification of therapeutic targets are emergent. Lipid rafts (LRs) ar...
Supported by Development funds from Section of Gastroenterology/Hepatology, Internal Medicine, University of Nebraska Medical Center
Alcoholic patients have a high incidence of hepatitis C virus (HCV) infection. Alcohol consumption enhances the severity of the HCV disease course and worsens the outcome of chronic hepatitis C. The accumulation of ...
Hepatitis C virus (HCV) infects approximately 170 million individuals worldwide. Prevention of HCV infection complications is based on antiviral therapy with the combination of pegylated interferon alfa and ribavirin....