SPHINGOSINE

作品数：80被引量：236H指数：8
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相关领域：医药卫生更多>>
相关作者：张翼肖琼尹大力徐美林王菁更多>>
相关机构：北京协和医学院首都医科大学天津市胸科医院天津医科大学更多>>
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相关基金：国家自然科学基金广东省自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
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Sphingosine-1-phosphate derived from PRP-Exos promotes angiogenesis in diabetic wound healing via the S1PR1/AKT/FN1 signalling pathway被引量：4
《Burns & Trauma》2023年第1期229-244,共16页Tianyi Chen Peiyang Song Min He Shunli Rui Xiaodong Duan Yu Ma David G.Armstrong Wuquan Deng 
supported by the Chongqing Youth High-end Talent Studio(Grant No.ZQNYXGDRCGZS2021008);the fund of Sichuan Provincial Western Psychiatric Association’s CSPC LEADING Scientific Research Project(Grant No.WL2021002);the Natural Science Foundation of Chongqing Municipal Science and Technology Bureau(CSTB2022NSCQ-MSX0489);partially supported by National Institutes of Health,National Institute of Diabetes and Digestive and Kidney Diseases Award Number 1R01124789-01A1;National Science Foundation(NSF)Center to Stream Healthcare in Place(#C2SHiP)CNS Award Number 2052578 awarded to DGA.
Background:Sphingosine-1-phosphate(S1P),a key regulator of vascular homeostasis and angiogenesis,is enriched in exosomes derived from platelet-rich plasma(PRP-Exos).However,the potential role of PRP-Exos-S1P in diabet...
关键词：EXOSOMES Platelet-rich plasma Diabetic foot ulcer Wound healing Sphingosine-1-phosphate 
The predictive value of serum S1P and STIM1 levels after PCI for in-stent restenosis and their correlation with angiogenesis and inflammatory response
《Journal of Hainan Medical University》2017年第13期71-74,共4页Fang Wang Xiao-Yun Ding Guo Lyu Zhen-Guo Liu Hong-Jun Li Li-Ke Geng Ning Guo 
Natural Science Foundation of China No:81170138.
Objective:To study the predictive value of serum S1P and STIM1 levels after percutaneous coronary intervention (PCI) for in-stent restenosis and their correlation with angiogenesis and inflammatory response.Methods:13...
关键词：PERCUTANEOUS CORONARY intervention Sphingosine-1-phosphate STROMAL interaction molecule 1 ANGIOGENESIS Inflammatory response 
Roles of sphingosine 1-phosphate on tumorigenesis被引量：5
《World Journal of Biological Chemistry》2011年第2期25-34,共10页Hsinyu Lee 
Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid with a variety of biological activities.It is generated from the conversion of ceramide to sphingosine by ceramidase and the subsequent conversion of sphingosi...
关键词：SPHINGOSINE 1-phosphate SPHINGOSINE KINASE CERAMIDE ANGIOGENESIS Autophagy TUMORIGENESIS 
Sphingosine-1-phosphate signaling in vasculogenesis and angiogenesis被引量：6
《World Journal of Biological Chemistry》2010年第10期291-297,共7页Kelley M Argraves Brent A Wilkerson W Scott Argraves 
Supported by Grants from the United States Public Health Service/National Institutes of Health, No. HL080404, HL094883 (Argraves KM) and HL061873, HL095067 (Argraves WS);NIH Training Grant to Improve Cardiovascular Therapies HL007260 (Wilkerson BA);American Heart Association 10PRE3910006 (Wilkerson BA)
Blood vessels either form de novo through the process of vasculogenesis or through angiogenesis that involves the sprouting and proliferation of endothelial cells in pre-existing blood vessels. A complex interactive n...
关键词：Sphingosine-1-phosphate VASCULOGENESIS ANGIOGENESIS G-protein-coupled receptors ENDOTHELIUM 
Roles of sphingosine-1-phosphate signaling in angiogenesis被引量：5
《World Journal of Biological Chemistry》2010年第10期298-306,共9页Yoh Takuwa Yasuo Okamoto Noriko Takuwa Kazuaki Yoshioka 
Supported by Grants from the Ministry of Education, Science, Sports and Culture of Japan and the Japan Society for the Promotion of Science;the Practical Application Research program of Japan Science and Technology Agency Innovation plaza Ishi-kawa
Sphingosine-1-phosphate (S1P) is a blood-borne lipid mediator with pleiotropic biological activities. S1P acts via the specific cell surface G-protein-coupled receptors, S1P1-5. S1P1 and S1P2 were originally identifie...
关键词：Sphingosine-1-phosphate ANGIOGENESIS Angiogenic therapy Rac Akt Vascular MATURATION Endothelial CELLS Bone-marrow-derived CELLS 
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