supported by Shenzhen Key Medical Discipline Construction Fund (grant SZXK028);Shenzhen Science and Technology Program (grant JCYJ20210324141403009,RCYX20210609104608036);Natural Science Funding of China (grant 82201851).
Introduction Macrophages,a major immune cell type constituting the human innate immune system,are involved in various physiological processes,such as tissue development,remodeling,homeostasis,and repair,crucial for ma...
This work was supported by the Project of‘0 to 1’of Sichuan University(grant No.2022SCUH0033);the 1·3·5 Project for Disciplines of Excellence Clinical Research Incubation Project,West China Hospital of Sichuan University(grant Nos.2019HXFH056,2020HXFH048,and ZYJC21060).
Infantile hepatic hemangiomas(IHHs)are common benign tumors seen in the liver of infants.IHHs are true infantile hemangiomas(IHs)and have phases of proliferation and involution parallel to those of cutaneous IHs.The d...
Tissue-engineered products commercially available today have been limited to thin avascular tissue such as skin and cartilage.The fabrication of thicker,more complex tissue still eludes scientists today.One reason for...
Synergies in bioprinting are appearing from individual researchers focusing on divergent aspects of the technology.Many are now evolving from simple mono-dimensional operations to model-controlled multi-material,inter...
supported by the NCI grants(CA118762 and CA156744)to Yi Sun.
SAG(Sensitive to Apoptosis Gene),also known as RBX2(RING box protein 2),ROC2(Regulator of Cullins 2),or RNF7(RING Finger Protein 7),was originally cloned in our laboratory as a redox inducible antioxi-dant protein and...
Vascular formation in vivo involves several processes and signal cascades subsequently occurring in the embryo. Several models by ES cells have been reported for analysis in vitro. We show here a 3D culture system usi...
This study was supported by grants from the National Natural Science Foundation of China(Grant No.30971138);the Science Foundation of Suzhou City(No.SWG0904 and No.SS201004);a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD),and a Special National Strategic Leader Project of China(No.XDA01040200).
Antitumor angiogenic therapy has been shown promising in the treatment of several advanced cancers since the approval of the first antiangiogenic drug Avastin in 2004.Although the current antiangiogenic drugs reduce t...
Background Cellular repressor of ElA-stimulated genes(CREG) is homeostatic modulated gene,which regulate a number of cellular processes,including cell differentiation, motility and survival.Previous studies have demon...
Background Mesenchymal stem cells (MSCs) transplantation may partially restore heart function in the treatment of acute myocardial infarction (AMI). The aim of this study was to explore the beneficial effects of M...
Supported by Grants from the United States Public Health Service/National Institutes of Health, No. HL080404, HL094883 (Argraves KM) and HL061873, HL095067 (Argraves WS);NIH Training Grant to Improve Cardiovascular Therapies HL007260 (Wilkerson BA);American Heart Association 10PRE3910006 (Wilkerson BA)
Blood vessels either form de novo through the process of vasculogenesis or through angiogenesis that involves the sprouting and proliferation of endothelial cells in pre-existing blood vessels. A complex interactive n...