supported by the National Natural Science Foundation of China under Grant No.62075235,National Key R&D Program of China under Grant No.2021YFF0700700;Gusu Innovation and Entrepreneurship Leading Talents in Suzhou City under Grant No.ZXL2021425;Youth Innovation Promotion Association of the Chinese Academy of Sciences under Grant No.2019320;Innovation of Scientific Research Strategic Priority Research Program of the Chinese Academy of Sciences under Grant No.XDA15021304.
The parafoveal area,with its high concentration of photoreceptors andfine retinal capillaries,is crucial for central vision and often exhibits early signs of pathological changes.The current adaptive optics scanning l...
Total pancreatectomy(TP) is a surgical procedure which includes the complete removal of the pancreatic gland, the spleen, the duodenum, the gallbladder, and the distal part of the stomach. TP represents the curative t...
The field of vascular medicine has undergone a profound transformation in the 21st century,transforming our approach to assessment and treatment.Athero-sclerosis,a complex inflammatory disease that affects medium and ...
Supported by National Natural Science Foundation of China,No.82293665;Anhui Provincial Department of Education University Research Project,No.2023AH051763.
BACKGROUND The management of hepatoblastoma(HB)becomes challenging when the tumor remains in close proximity to the major liver vasculature(PMV)even after a full course of neoadjuvant chemotherapy(NAC).In such cases,e...
supported by research grants from the National Natural Science Foundation of China(81930011,91739304,and 31821091);the National Key R&D Program of China(2019YFA0801603);supported by a Postdoctoral Fellowship of the Peking-Tsinghua Center for Life Sciences;the China Postdoctoral Science Foundation(2022T150012).
Glioblastoma(GBM)causes nearly universal mortality as a result of the failure of conventional therapies including surgical resection,targeted radiation therapy,and chemotherapy.An increasingly important treatment opti...
Open Access funding enabled and organized by Projekt DEAL.
Two very recent back-to-back papers published in Nature1,2 decipher the holistic role of the aryl hydrocarbon receptor(AHR)/dietary-ligand axis,in enteric and pulmonary vasculature to emphasize tolerance induction and...
the Ethics Committee of the Polytechnic Institute of Coimbra(no.11 CEIPC/2019).
Objectives:Investigate whether partial sleep deprivation for five nights causes vascular changes in healthy university students.Study design:Prospective observational study.Methods:The study involved 18 young and heal...
supported by the National Natural Science Foundation of China[82172711];the Natural Science Foundation of Guangdong Province[2019A1515011786];the Bethune Charitable Foundation[zllcaxw-15].
Background:Gastric cancer brain metastasis(GCBM)represents a rare but highly aggressive malignancy.Metastatic cancer cells are highly heterogeneous and differentially remodels brain vasculature and immune microenviron...
National Key Research and Development Program of China,Grant/Award Numbers:2021YFA1201200,2021YFF1200404;National Natural Science Foundation of China,Grant/Award Numbers:U1967217,22176137;National Independent Innovation Demonstration Zone Shanghai Zhangjiang Major Projects,Grant/Award Number:ZJZX2020014;National Center of Technology Innovation for Biopharmaceuticals,Grant/Award Number:NCTIB2022HS02010;Shanghai Artificial Intelligence Lab,Grant/Award Number:P22KN00272;Starry Night Science Fund of Zhejiang University Shanghai Institute for Advanced Study,Grant/Award Number:SN-ZJU-SIAS-003;Natural Science Foundation of the Jiangsu Higher Education Institutions of China,Grant/Award Number:20KJA150010;Natural Science Foundation of Zhejiang Province,Grant/Award Number:2022LQ22H220001。
The efficacy of nanoparticle(NP)-based drug delivery technology is hampered by aberrant tumor stromal microenvironments(TSMs)that hinder NP transportation.Therefore,the promotion of NP permeation into deep tumor sites...
Texas A&M University Microscopy and Imaging Center Core Facility(RRID:SCR_022128);the Integrated Microscopy and Imaging Laboratory at Texas A&M College of Medicine(RRID:SCR_021637)for providing microscopy resources.
Vascularization is a key pre-requisite to engineered anatomical scale three dimensional(3-D)constructs to ensure their nutrient and oxygen supply upon implantation.Presently,engineered pre-vascularized 3-D tissues are...