云南高校图书馆联盟文献共享服务平台- TETRAMETHYLPYRAZINE

TETRAMETHYLPYRAZINE: 作品数：58被引量：265H指数：9; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：文志斌贺石林何晓凡庄沛张婉玉更多>>; 相关机构：中南大学齐鲁工业大学天津科技大学沈阳华泰药物研究所更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金湖北省自然科学基金山东省科技发展计划项目国家高技术研究发展计划更多>>

Tetramethylpyrazine and paeoniflorin combination(TMP-PF)inhibits angiogenesis in atherosclerosis via miR-126/VEGF/VEGFR2 signaling pathway被引量：1: 《Journal of Future Foods》2024年第3期280-287,共8页Yahui Yuan Rong Yuan Qiqi Xin Yu Miao Ying Chen Rui Gao Weihong Cong; supported by the National Natural Science Foundation of China(82004193);CACMS Innovation Fund(CI 2021A00914);the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ14-YQ-007).; Angiogenesis in atherosclerosis(AS)promotes plaque destabilization.miR-126 has a significant role in angiogenesis.Tetramethylpyrazine(TMP)and paeoniflorin(PF)have anti-atherosclerotic effects.However,the miR-126-relat...; 关键词：ATHEROSCLEROSIS ANGIOGENESIS TETRAMETHYLPYRAZINE PAEONIFLORIN miR-126/VEGF/VEGFR2 signaling pathway

Research Progress on the Anti-Atherosclerotic Effect and Mechanism of Tetramethylpyrazine: 《Journal of Clinical and Nursing Research》2024年第6期94-99,共6页Shengyang Gong Zheng Cao; Atherosclerosis is a chronic vascular disease and the most common pathological change of cardiovascular disease.Its pathogenesis is closely related to inflammation,oxidative stress,lipid accumulation,and calcinosis.Te...; 关键词：ATHEROSCLEROSIS Chinese medicine TETRAMETHYLPYRAZINE Mechanism of action Research progress

Tetramethylpyrazine analogue T-006 promotes clearance of alpha-synuclein by enhancing proteasome activity in Parkinson disease models被引量：1: 《中国药理学与毒理学杂志》2019年第9期658-659,共2页ZHOU He-feng SHAO Min GUO Bao-jian LI Chu-wen LU Yu-cong YANG Xuan-jun LI Sheng-nan LI Hai-tao ZHU Qi ZHONG Han-bing WANG Yu-qiang ZHANG Zai-jun LU Jia-hong LEE Ming-yuen Simon; Science and Technology Development Fund(FDCT)of Macao SAR(069/2015/A2;134/2014/A3;062-2017-AIR);Research Committee,University of Macao(MYRG2015-00182-ICMS-QRCM;MYRG2015-00214-ICMSQRCM;MYRG139(Y1-L4)-ICMS12-LMY;and MYRG2016-00129-ICMS-QRCM); OBJECTIVE To investigate the effects of T-006(tetramethylpyrazine derivative)in promotingα-Synuclein(α-Syn)degradation and evaluated the neuroprotective effects in cellular and animalα-Syn model of Parkinson diseas...; 关键词：Α-SYNUCLEIN degradation LMP7 proteasome activity Parkinson disease

Protective Effects of Tetramethylpyrazine on Cerebrovascular Regulations in Rats with Chronic Alcoholic Encephalopathy被引量：6: 《Biomedical and Environmental Sciences》2015年第9期691-695,共5页LI Hui YANG Xue SHI Wei MA Zhao FENG Guang Kun YIN Yan Ling FAN Yan Xia JIANG Jie; supports from Shandong Academy of Medical Sciences,Electron Microscopy Laboratory of Shandong University Medical School;Department of Neurology of Qilu Hospital of Shandong University; Recent studies showed that pathology of alcoholic encephalopathy was associated with cerebral vascular damage.TMP（tetramethylpyrazine）is widely used in the treatment of cerebrovascular diseases,however,it has not be...; 关键词：alcohol encephalopathy Alcohol saline relieve intake neuronal administration Figure tetramethyl

Expression of soluble vascular endothelial growth factor receptor-1 and placental growth factor in fetal growth restriction cases and intervention effect of tetramethylpyrazine被引量：3: 《Asian Pacific Journal of Tropical Medicine》2014年第8期663-667,共5页Shu-Wei Li Yi Ling Song Jin Ye-Fei Lin Ze-Jun Chen Chun-Xia Hu Ming-Hua Wang Mao-Zhong Yao; supported by Natural Science Foundation of Hainan Province,2010(Qiong Science 310152);Science project of Hainan Province(081006);Foundation of Hainan Hainan Ministry of Health(Qiong.Hygiene 2010-40); Objective:To investigate the expression of soluble vascular endothelial growth factor receptor-1(sFlt-1) and placental growth factor(PLGF) in the fetal growth restriction(FGR) cases and the intervention mechanism of t...; 关键词：LIGUSTRAZINE Fetal growth restriction SFLT-1 PLGF

Effects of different concentrations of tetramethylpyrazine,an active constituent of Chinese herb, on human corneal epithelial cell damaged by hydrogen peroxide被引量：2: 《International Journal of Ophthalmology(English edition)》2014年第6期947-951,共5页Na Li Xin-Guo Deng Shi-Hua Zhang Mei-Feng He Dong-Qing Zhao; Supported by Guangdong Administration of Traditional Chinese Medicine (No.2007095); AIM: To discuss the effects of different concentrations of tetramethylpyrazine(TMP), an active constituent of Chinese herb, on damaged Shandong human corneal epithelial cell(SDHCEC) induced by hydrogen peroxide.METHOD...; 关键词：human corneal epithelial cell cell viability APOPTOSIS hydrogen peroxide

Medium-and long-term efficacy of ligustrazine plus conventional medication on ischemic stroke: a systematic review and meta-analysis被引量：6: 《Journal of Traditional Chinese Medicine》2013年第6期715-720,共6页Xiaojia Ni Shaonan Liu Xinfeng Guo; Supported by Joint Special Project of Guangdong Provincial Department of Science and Technology-Guangdong Provincial Academy of Chinese Medical Sciences:Construction and Application of Evidence-Based Knowledge Management System for Traditional Chinese Medicine(No.2012A032500009); OBJECTIVE： To evaluate the medium- to long-term efficacy of ligustrazine plus conventional medicine treating ischemic stroke. METHODS： Randomized controlled trials （RCTs） testing ligustrazine in the treatment of a...; 关键词：TETRAMETHYLPYRAZINE STROKE Time Sec-ondary prevention Review META-ANALYSIS

Antidepressant-Like Activity of Tetramethylpyrazine Measured by Chronic Experimental Method in Rat Model of Depression被引量：1: 《Pharmacology & Pharmacy》2012年第1期52-57,共6页Lijian Yu Xiaodan Jiang Yongping Zhang Mingneng Liao Rundi Ma Tingxi Yu; The aim of this study was to investigate the potential antidepressive-like effect of tetramethylpyrazine (TMP), one of available blood-activating and stasis-eliminating components from traditional Chinese medicines, i...; 关键词：TETRAMETHYLPYRAZINE Antidepressive-Like ACTIVITY CHRONIC MILD Stress Rats

Antidepressant-Like Effect of Tetramethylpyrazine in Mice and Rats被引量：1: 《Neuroscience & Medicine》2011年第2期142-148,共7页Lijian Yu Xiaodan Jiang Mingneng Liao Rundi Ma Tingxi Yu; The aim of this study was to investigate the potential antidepressive-like effect of tetramethylpyrazine (TMP), one of available blood-activating and stasis-eliminating components from traditional Chinese medicines, a...; 关键词：TETRAMETHYLPYRAZINE (TMP) Antidepressive-Like ACTIVITY MICE RATS Monoaminergic NEUROTRANSMITTER

Tetramethylpyrazine在视网膜色素上皮细胞变性及脉络膜血流和RPE细胞氧化应激中的作用(英文)被引量：7: 《国际眼科杂志》2010年第10期1843-1847,共5页沈轶庄沛林宝琴张婉玉 George C Y Chiou; 目的:研究1%Tetramethylpyrazine(TMP)在视网膜色素上皮细胞(RPE)变性,脉络膜血流和RPE细胞氧化应激中的作用。方法:在碘酸钠诱导的大鼠RPE变性研究中,1%TMP滴眼液预先处理1wk,3次/d,1wk后予碘酸钠舌下静脉注射,在2wk和4wk末,视网膜电图...; 关键词：TETRAMETHYLPYRAZINE 碘酸钠视网膜色素上皮细胞年龄相关性黄斑变性脉络膜血流氧化应激

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