LIGUSTRAZINE

作品数：64被引量：199H指数：8
导出分析报告
相关作者：辛志军陈方王迎伟汤仁仙董红燕更多>>
相关机构：暨南大学遵义医学院附属医院徐州医学院南京医科大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金中国博士后科学基金江苏省自然科学基金广东省自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Ligustrazine Attenuates Hyperhomocysteinemia-induced Alzheimer-like Pathologies in Rats被引量：8
《Current Medical Science》2021年第3期548-554,共7页Qing ZHANG Jing WANG Liang ZHU Shi-jie JIANG Juan LIU Lin-xiao WANG Xi-hu QIN 
grants from Changzhou Sci&Tech Program(No.CJ20190063,No.CJ20200090);Young Talent Development Plan of Changzhou Health Commission(No.CZQM2020078,and No.CZQM2020063);China Postdoctoral Science Foundation(No.2020M670012ZX);National Natural Science Foundation of China(No.81803498);Jiangsu Planned Projects for Postdoctoral Research Funds(No.2019K157);"Mass Entrepreneurship and Innovation Plan"of Jiangsu Province(No.QT201919).
Ligustrazine,an alkaloid extracted from the traditional Chinese herbal medicine Ligusticum Chuanxiong Hort,has been clinically applied to treat the cerebrovascular diseases.Hyperhomocystcincmia(Hhcy)is an independent ...
关键词：Alzheimer's disease LIGUSTRAZINE HYPERHOMOCYSTEINEMIA phosphorylated tau cognitive impairment 
Design, synthesis, and biological evaluation of ligustrazine/resveratrol hybrids as potential anti-ischemic stroke agents被引量：9
《Chinese Journal of Natural Medicines》2020年第8期633-640,共8页ZHANG Yin-Qiu WU Jian-Bing YIN Wei ZHANG Yi-Hua HUANG Zhang-Jian 
supported by the National Natural Science Foundation of China(Nos.81822041;81773573;21977116;and 81673305);the National Science&Technology Major Project“Key New Drug Creation and Manufacturing Program”(No.2018ZX09711002-006-013);the Open Project of State Key Laboratory of Natural Medicines(No.SKLNMZZCX201824);the State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia Fund(No.SKL-HIDCA-2018-1);part of the work was supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX18_0795)。
To search for potent anti-ischemic stroke agents,a series of tetramethylpyrazine(TMP)/resveratrol(RES)hybrids 6 a-t were designed and synthesized.These hybrids inhibited adenosine diphosphate(ADP)-or arachidonic acid(...
关键词：LIGUSTRAZINE RESVERATROL HYBRIDS Anti-platelet aggregation ANTIOXIDANT Ischemic stroke 
Effect of Prednisone and Cyclophosphamide combine with ligustrazine injection on immunologic function and other related factors in patients with systemic lupus erythematosus
《Journal of Hainan Medical University》2019年第11期33-37,共5页Zhi-Min Lyu Jing Gu Li-Ping Ye 
Objective:To investigate the effect of prednisone and cyclophosphamide combine with ligustrazine injection on immunologic function and other related factors in patients with systemic lupus erythematosus (SLE).Methods:...
关键词：Systemic lupus ERYTHEMATOSUS PREDNISONE CYCLOPHOSPHAMIDE LIGUSTRAZINE injection IMMUNOLOGIC function 
Effects of Ligustrazine on Airway Inflammation in A Mouse Model of Neutrophilic Asthma被引量：5
《Chinese Journal of Integrative Medicine》2018年第5期353-358,共6页LIU Xiao-ming1 WANG Yong-bin2 WU Qian2 BIAN Zhong-rui2 CHE Xiao-wen2 
Supported by the Key Scientific and Technological Project of Shandong Province(No.2014GSF119012);China
Objective: To investigate the effects of ligustrazine(LTZ) on airway inflammation in a mouse model of neutrophilic asthma(NA). Methods: Forty healthy C57 BL/6 female mice were randomly divided into 4 groups using a ra...
关键词：LIGUSTRAZINE neutrophilic asthma airway inflammation CYTOKINE 
Study on Rheology and Release Kinetics of Chuanqi Ophthalmic Microemulsion in situ Gel
《Medicinal Plant》2018年第2期68-72,共5页Maobo DU Yamei LIU Aiping HE Yao YAO Shuzhi LIU 
Supported by Project of National Natural Science Foundation(81373977)
[Objectives] To study the rheology and release kinetics of Chuanqi ophthalmic microemulsion in situ gel,so as to provide references for its future study and development. [Methods]The fluid properties and linear viscoe...
关键词：RHEOLOGY Linear viscoelastic region Ophthalmic in situ gel MICROEMULSION Chuanqi prescription LIGUSTRAZINE LIGUSTILIDE 
Clinical study of adjuvant therapy on ischemic stroke with salviae miltiorrhizae and ligustrazine被引量：3
《Journal of Acute Disease》2017年第1期36-40,共5页Jing-Qin Tian Wei Zhang 
Objective: To study the effect of adjuvant therapy with salviae miltiorrhizae and ligustrazine injection on neural function injury, degree of oxidative stress reaction, chemotactic factor and adhesion molecule in pati...
关键词：ISCHEMIC STROKE Salviae miltiorrhizae and LIGUSTRAZINE Neural function OXIDATIVE stress reaction Chemotactic factor Adhesion MOLECULE 
Effect of adjuvant salvia miltiorrhiza and ligustrazine therapy on renal function, renal blood perfusion as well as CTGF and TGF-β1 content in patients with chronic renal failure被引量：3
《Journal of Hainan Medical University》2017年第1期64-67,共4页Hai-Yu Guan 
Objective:To analyze the effect of adjuvant salvia miltiorrhiza and ligustrazine therapy on renal function, renal blood perfusion as well as connective tissue growth factor (CTGF) and transforming growth factor (TGF)-...
关键词：Chronic RENAL failure SALVIA miltiorrhiza and LIGUSTRAZINE THERAPY RENAL function RENAL blood perfusion 
Effect of Ligustrazine Nanoparticles Nano Spray on Transforming Growth Factor-β/Smad Signal Pathway of Rat Peritoneal Mesothelial Cells Induced by Tumor Necrosis Factor-α被引量：5
《Chinese Journal of Integrative Medicine》2016年第8期629-634,共6页颜帅 杨斓 乐音子 李文林 曾莉 乐进 毛春芹 
Supported by the National Natural Science Foundation of China(No.81373843);College Graduate Student Innovative Research Fund of Jiangsu Province,China(No.CXZZ13-0613);Administration of Traditional Chinese Medicine Science and Technology Project of Jiangsu Province,China(No.LZ13006)
Objective： To study the effect of ligustrazine nanoparticles nano spray（LNNS） on transforming growth factor β（TGF-β）/Smad signal protein of rat peritoneal mesothelial cells（RPMC） induced by tumor necrosis fac...
关键词：peritoneal mesothelial cells ligustrazine experimental research transforming growth factor β/Smad 
Pretreatment with a combination of ligustrazine and berberine improves cardiac function in rats with coronary microembolization被引量：22
《Acta Pharmacologica Sinica》2016年第4期463-472,共10页Ying ZHANG Xiao-juan MA Chun-yu GUO Ming-ming WANG Na KOU Hui-min MAO Da-zhuo SHI 
Aim： We have shown that a combination of ligustrazine and berberine produces more effective inhibition on platelet activation and inflammatory reactions in rat acute myocardial infarction compared with either agent a...
关键词：coronary microembolization LIGUSTRAZINE BERBERINE CLOPIDOGREL CARDIOPROTECTION platelet activation inflammatory reactions 
Changes of NF-κB, Bax and Caspase 3 in Apoptosis Induced by Ligustrazine Combined with Cis-dichlorodiamine Platinum in Human Gastric Carcinoma SGC-7901 Cell Lines被引量：1
《Agricultural Science & Technology》2015年第7期1357-1359,共3页Tao HUANG Liyan LI Xiaona GUO Zhigang GUO Yalin Zhang 
Supported by the Fund for Excellent Young Teachers by Education Department of Henan(2010GGJS-224)
[Objective] This study aimed to investigate the mechanism of apoptosis induced by ligustrazine(TMP) and cis-dichlorodiamine platinum(DDP) in SGC-7901 cell lines in vitro. [Methods] SGC-7901 cell lines were treated wit...
关键词：LIGUSTRAZINE Cis-dichlorodiamine pliatinum （DDP） Human gastric carci-noma APOPTOSIS 
全选清除导出
共7页<1234567>
检索报告 对象比较 聚类工具 使用帮助 返回顶部