染色体免疫共沉淀测序(Chromatin immunoprecipitation followed by sequencing,ChIP-seq)是研究DNA-蛋白质互作的有力工具,被广泛用于RNA聚合酶、转录因子和组蛋白修饰等在基因组上的精确定位。近年来,在ChIP-seq技术的基础上,科学家...
Supported by the National Basic Research Program of China(2014CB744600);National Natural Science Foundation of China(61431019,61671430);Chinese Academy of Sciences Key Project Targeting Cutting-Edge Scientific Problems(QYZDB-SSW-JSC011);Instrument Development Program of the Chinese Academy of Sciences and Youth Innovation Promotion Association of Chinese Academy of Sciences。
supported by the National Basic Research Program of China (2013CB966901);the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA01040108);the National Natural Science Foundation of China (31271592, 31570995) to T.Z. and (31400831) to J.C
Recently,Zhou et al.[1]have successfully traced the hematopoietic stem cell(HSC)specification during the stepwise development of HSC from the pre-HSC stage at single-cell resolution.These findings offer fundamental in...