CD38 is a versatile, ubiquitously expressed protein that was identified as a multifunctional enzyme. Recently, cumulating evidence has suggested that CD38 is involved in autophagy, which is an evolutionarily conserved...
This work was supported by the grants from the Council of Hong Kong (Nos. 769107, 768408, 769309 and 770610) and the National Natural Science Foundation of China/the Research Grants Council ofHong Kong (No. N_HKU 722/08).
Cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP) are Ca2+-mobilizing nucleotides that were discovered in the late 1980s. Two decades of investigations have built up a considerab...
supported by the Research Grants Council of Hong Kong(Grant Nos.769107,768408, 769309 and 770610);the National Natural Science Foundation of China/the Research Grants Council of Hong Kong(Grant No.N_HKU 722/08)
The concept advanced by Berridge and colleagues that intracellular Ca2+-stores can be mobilized in an agonist-dependent and messenger(IP3)-mediated manner has put Ca 2+-mobilization at the center stage of signal trans...