NOD2/CARD15

作品数:35被引量:146H指数:7
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相关领域:医药卫生更多>>
相关作者:智发朝张以洋龙靖华钟长青张迎春更多>>
相关机构:南方医科大学南方医院浙江大学医学院附属邵逸夫医院江苏省中医院吉林大学更多>>
相关期刊:《世界核心医学期刊文摘(胃肠病学分册)》《中华消化杂志》《World Journal of Gastroenterology》《Gastroenterology Report》更多>>
相关基金:广东省自然科学基金国家自然科学基金广西壮族自治区自然科学基金新疆维吾尔自治区自然科学基金更多>>
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Blau综合征NOD2/CARD15基因突变及临床特征分析被引量:1
《中国皮肤性病学杂志》2021年第8期849-854,共6页张高磊 顾菲 苏伟 杨明 张升 蒋丽潇 朱芸 秦琴 曹会娜 李倩 刘晓雁 
国家自然科学基金(81974473,82073461)。
目的回顾总结4个Blau综合征家系先证者患儿及其父母NOD2/CARD15基因突变及临床特征。方法采用PCR扩增4个家系所有成员的NOD2/CARD15基因所有外显子。Sanger法测序NOD2基因所有外显子序列,Ensembl和NCBI dbSNP基因数据库比对确定致病位点...
关键词:Blau综合征 NOD2/CARD15基因 基因突变 遗传 临床特征 
TLR2、TLR4和NOD2/CARD15基因多态性与溃疡性结肠炎相关性的meta分析被引量:6
《胃肠病学》2021年第2期82-90,共9页夏宇 李健 高鸿亮 
新疆维吾尔自治区自然科学基金(2015211C087)。
背景:近年我国溃疡性结肠炎(UC)的患病率明显增高,Toll样受体2(TLR2)、TLR4和NOD2/CARD15基因多态性与UC的发生、发展可能密切相关。目的:探讨TLR2、TLR4和NOD2/CARD15基因多态性对UC发生的影响。方法:计算机检索PubMed、中国生物医学...
关键词:结肠炎 溃疡性 TOLL样受体 NOD2/CARD15 基因多态性 META分析 
Auto-inflammatory diseases in ileal pouch patients with NOD2/CARD15 mutations
《Gastroenterology Report》2016年第1期73-76,I0003,共5页Darren N.Seril Qingping Yao Bo Shen 
supported by the Ed and Joey Story Endowed Chair.The manuscript received no direct financial support.
Pouchitis is common in ulcerative colitis patients undergoing total proctocolectomy with ileal pouch-anal anastomosis,and chronic antibiotic-refractory pouchitis occurs in a subgroup of the patients.Auto-inflammatory ...
关键词:auto-inflammation ileal pouch POUCHITIS restorative proctocolectomy ulcerative colitis 
NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease被引量:3
《World Journal of Gastroenterology》2015年第25期7786-7794,共9页Aziza Boukercha Hamida Mesbah-Amroun Amira Bouzidi Houria Saoula Mhamed Nakkemouche Maryline Roy Jean-Pierre Hugot Chafia Touil-Boukoffa 
Supported by the Agence Thématique de la Recherche Scientifique en Santé,(ATRSS,ex ANDRS)(PNR N°37-ANDRS-2011)
AIM: To analyse allelic frequency of NOD2 gene variantsand to assess their correlation with inflammatory bowel disease(IBD) in Algeria.METHODS: We studied 132 unrelated patients diagnosed with IBD, 86 with Crohn's dis...
关键词:Algeria Crohn's DISEASE ULCERATIVE colitis Inflammatory BOWEL DISEASE NOD2 mutations polymerasechain reaction-restriction fragment length polymorphismmethod 
Prediction of Crohn's disease aggression through NOD2/CARD15 gene sequencing in an Australian cohort被引量:1
《World Journal of Gastroenterology》2014年第17期5008-5016,共9页Maneesha Bhullar Finlay Macrae Gregor Brown Margie Smith Ken Sharpe 
Supported by Schering Plough
AIM: To investigate the association between mutations in oligomerisation domain 2/caspase recruitment domains 15 (NOD2/CARD15) and the natural history of Crohn’s disease (CD) to identify patients who would ben...
关键词:Inflammatory bowel disease  Oligomerisation domain 2/caspase recruitment domains 15  Genotyping  Crohn’ s disease  Natural history 
Association between NOD2/CARD15 gene polymorphisms and Crohn's disease in Chinese Zhuang patients被引量:7
《World Journal of Gastroenterology》2014年第16期4737-4744,共8页Wei-Yan Long Lan Chen Cui-Liang Zhang Rong-Mao Nong Mei-Jiao Lin Ling-Ling Zhan Xiao-Ping Lv 
Supported by Guangxi Graduate Education Innovation Project Fund,No.YCSZ2012035;the Natural Science Foundation of Guangxi Zhuang Autonomous Region,No.0832009,No.2012GXNSFAA053143;Traditional Chinese Medicine Science Fund of Guangxi Zhuang Autonomous Region,China,No.GZPT1238
AIM: To assess the relationship between the P268S, JW1 and N852S polymorphisms and Crohn’s disease (CD) susceptibility in Zhuang patients in Guangxi, China.
关键词:Crohn’ s disease  NOD2/CARD15  Single nucleotide polymorphisms 
Role of ATG16L,NOD2 and IL23R in Crohn's disease pathogenesis被引量:5
《World Journal of Gastroenterology》2012年第5期412-424,共13页Saleh A Naser Melissa Arce Anam Khaja Marlene Fernandez Najih Naser Sammer Elwasila Saisathya Thanigachalam 
Supported by The Broad Foundation grant,No. IBD-0207R
Inflammatory bowel disease is a group of diseases that includes Crohn's disease (CD) and ulcerative colitis. CD is characterized as a chronic inflammatory disease of the gastrointestinal tract, ranging from the mou...
关键词:Crohn's disease ATG16L NOD2/CARD15 IBDS CTLA4 TNFSF15 IL23R 
Risk factors and gene polymorphisms of inflammatory bowel disease in population of Zhejiang,China被引量:16
《World Journal of Gastroenterology》2011年第1期118-122,共5页Zi-Wei Wang Feng Ji Wei-Jun Teng Xiao-Gang Yuan Xiao-Ming Ye 
AIM:To identify the risk factors and three single nucleotide polymorphisms(SNPs) of NOD2/CARD15 gene in inflammatory bowel disease(IBD) of the population in Zhejiang,China.METHODS:A case-control study was conducted us...
关键词:Inflammatory bowel disease Risk factors EPIDEMIOLOGY Gene polymorphism NOD2/CARD15 gene 
NOD2/CARD15 , ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn’s disease被引量:7
《World Journal of Gastroenterology》2010年第14期1753-1758,共6页Maria Gazouli Ioanna Pachoula Ioanna Panayotou Gerassimos Mantzaris George Chrousos Nicholas P Anagnou Eleftheria Roma-Giannikou 
AIM: To assess whether the polymorphisms of NOD2/ CARD15 , autophagy-related 16-like 1 (ATG16L1 ), and interleukin-23 receptor (IL23R ) genes play a more critical role in the susceptibility of childhood-onset than in ...
关键词:GENETICS CHILDHOOD-ONSET Inflammatory bowel disease Crohn’s disease Genetic susceptibility NOD2/CARD15 ATG16L1 IL23R POLYMORPHISMS 
日本血吸虫卵对TNBS诱导小鼠结肠炎肠黏膜表达NOD2/CARD15的影响
《复旦学报(医学版)》2010年第2期162-166,共5页夏晨梅 张顺财 
目的研究日本血吸虫卵对2,4,6-三硝基苯磺酸(2,4,6-trinitrobenzesulfonic acid,2,4,6-TNBS)诱导小鼠结肠炎肠黏膜表达NOD2/CARD15的影响。方法实验小鼠(n=50)随机分成3组:正常对照组(n=10)、TNBS+生理盐水组(n=20)和TNBS+日本血吸虫卵...
关键词:2 4 6-三硝基苯磺酸 血吸虫卵 NOD2/CARD15 炎症性肠病 小鼠 
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