OLIGONUCLEOTIDE

作品数：101被引量：206H指数：7
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相关领域：医药卫生生物学更多>>
相关作者：潘世扬刘锋何昆束永前汤新景更多>>
相关机构：北京大学首都医科大学南京医科大学中国科学院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Nucleobase,nucleoside,nucleotide,and oligonucleotide coordinated metal ions for sensing and biomedicine applications被引量：3
《Nano Research》2022年第1期71-84,共14页Jiaojiao Zhou Heyou Han Juewen Liu 
support from Natural Sciences and Engineering Research Council of Canada(NSERC);National Natural Science Foundation of China(No.21778020).
Metal ions play critical roles in chemical,biological,and environmental processes.Various biomolecules have the ability to coordinate with metal ions and form various materials.Nucleobases,nucleosides,and nucleotides,...
关键词：NUCLEOTIDES DNA metal ions self-assembly nanostructures 
PEGylation of therapeutic oligonucletides： From linear to highly branched PEG architectures被引量：1
《Nano Research》2018年第10期5519-5534,共16页Xueguang Lu Ke Zhang 
Financial support by the National Institute of General Medical Sciences Award Number 1R01GM121612-01, the National Science Foundation （CAREER Award Number 1453255）, and the American Chemical Society Petroleum Research Fund （No. PRF 54905-DNI5）, is acknowledged.
PEGylation, the attachment of poly（ethylene glycol） （PEG）, has been adopted to improve the pharmacokinetic properties of oligonucleotide therapeutics for nearly 30 years. Prior efforts mainly focused on the invest...
关键词：PEGYLATION OLIGONUCLEOTIDE brush polymer ANTISENSE small interfering RNA APTAMER PHOSPHOROTHIOATE 
Fluorescent nanoswitch for monitoring specific pluripotency-related microRNAs of induced pluripotent stem cells： Development of polyethyleneimine- oligonucleotide hybridization probes
《Nano Research》2017年第8期2545-2559,共15页Seungmin Han Hye Young Son Byunghoon Kang Eunji Jang Jisun Ki Na Geum Lee Jongjin Park Moo-Kwang Shin Byeonggeol Mun Jeong-Ki Min Seungjoo Haam 
The isolation of high-grade （i.e. high-pluripotency） human induced pluripotent stem cells （hiPSCs） is a decisive factor for enhancing the purity of hiPSC populations or differentiation efficiency. A non-invasive i...
关键词：induced pluripotent stem cells （iPSCs） PLURIPOTENCY microRNA （miRNA） fluorescence imaging nanoparticle 
Oligonucleotide delivery by chitosan-functionalized porous silicon nanoparticles被引量：2
《Nano Research》2015年第6期2033-2046,共14页Morteza Hasanzadeh Kafshgari Bahman Delalat Wing Yin Tong Frances J. Harding Martti Kaasalainen Jarno Salonen Nicolas H. Voelcker 
Porous silicon nanoparficles （pSiNPs） are a promising nanocarrier system for drug delivery owing to their biocompatibility, biodegradability, and non-inflammatory nature. Here, we investigate the fabrication and cha...
关键词：NANOPARTICLES porous silicon CHITOSAN gene delivery 
Effect of Nucleases on the Cellular Internalization of Fluorescent Labeled DNA-Functionalized Single-Walled Carbon Nanotubes被引量：7
《Nano Research》2008年第4期351-360,共10页Hye Kyung Moon Chan Il Chang Dong-Ki Lee Hee Cheul Choi 
This work was supported by the Nano/Bio Science&Technology Program of MOST(2008-00759);Korean Research Foundation(MOEHRD,KRF-2005-005-J13103 and KRF-2007-313-C00386);KOSEF(2007-8-1158).
Nuclease effects on the cell internalization of single-walled carbon nanotubes(SWNTs)functionalized with fluorescent-labeled DNA in serum containing cell growth media were examined.When Cy3-labeled DNA-functionalized ...
关键词：Single-walled carbon nanotube OLIGONUCLEOTIDE cellular delivery molecular transporter NUCLEASE 
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