相关期刊:《Acta Pharmacologica Sinica》《Science China Chemistry》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》更多>>
BACKGROUND Peptic ulcer(PU)is an abnormal phenomenon in which there is rupture of the mucosa of the digestive tract,which not only affects patients'normal life but also causes an economic burden due to its high medica...
This wofunded by the National Natural Science Foundation of China(No.81673497 and 81903695);the CAMS Innovation Fund for Medical Sciences(No.2016-I2M-1-001 and 2019-I2M-1-001);the Natural Science Foundation of Shandong Province[ZR2020MH419].
Liver fibrosis is one of the most severe pathologic consequences of chronic liver diseases,and effective therapeutic strategies are urgently needed.Proton pump inhibitors(PPIs)are H+/K+-ATPase inhibitors and currently...
Objective:To analyze the effect of pantoprazole and omeprazole in the treatment of patients with gastric ulcer.Methods:The treatment effect,recurrence rate,helicobacter pylori negative conversion rate,adverse reaction...
Pantoprazole sodium, a substituted benzimidazole derivative, is an irreversible proton pump inhibitor which is primarily used for the treatment of duodenal ulcers, gastric ulcers, and gastroesophageal reflux disease (...
The study aims to investigate the protein binding kinetics of nicotine and a PPI (pantoprazole) with Bovine Serum Albumin (BSA) through UV spectroscopy and computational modeling. Data was obtained by using nicotine a...
supported by National Key Technology R&D Program in the "Twelfth Five-Year" Plan of China(2011BAI11B07)
Background: This study evaluated the effect of omeprazole or pantoprazole on platelet reactivity in non-STsegment elevation acute coronary syndrome(NSTE-ACS) patients receiving clopidogrel.Methods: Consecutive patient...
The objective of this study was to investigate the pantoprazole and rebamipide efficiency on NSAIDs (nonsteroidal anti-inflammatory drugs)-gastropathy restoring and healing in patients with coronary heart disease, s...
Objective:Through the combination with hemocoagulase and pantoprazole on gastrointestinal bleeding, to observe the changes of serum BUN (blood urea nitrogen), LPO (LPO), NO (nitric oxide), TNF-α(TNF alpha), hs-CRP (h...
The article describes the pantoprazole healing effect on the gastroduodenal mucosa in patients with NSAID gastropathy. Two groups of patients were compared, depending on the treatment they have got group, which was ta...
BACKGROUND:This study aimed to compare pantoprazole,a proton-pomp inhibitors(PPIs),and ranitidine,a H2 receptor antagonists(H2RA),in ceasing dyspeptic symptoms in the emergency department(ED).METHODS:This randomized,d...