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supported by the Tianjin University of Traditional Chinese Medicine Scientific Research Project for the NewTeacher[grant number:XJS2022212];The Science and Technology Program of Tianjin[grant number:21YJDJC00020];The Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine[grant number:22HHZYSS00005].
Nano-targeted delivery systems have been widely used for breast tumor drug delivery.Estrogen receptors are considered to be significant drug delivery target receptors due to their overexpression in a variety of tumor ...
supported by NKEA Research Grant Scheme(NRGS)(NH1113D018-2)。
Objective:To investigate the bone-resorbing effect of demethylbelamcandaquinone B(Dmcq B)extracted from Marantodes pumilum var.alata on osteoclast differentiation in RAW264.7 cells.Methods:RAW264.7 macrophages were di...
Supported by the Research Affairs of Shiraz University of Medical Sciences(No.3001)
Objective: To investigate the impact of Humulus Lupulus L. hydroalcoholic extract on the body weights, reproductive organs, sperm quality and hormone levels in male rats. Methods: By simple random sampling method, sev...
In this study, we amplified aqnaporin I(AQP1) promoter sequence with polymerase chain reaction(PCR), then AQP1 promoter fragment and pGL2 basic vector were linked to create an artificial pGL2/AQP1 promoter re- por...
Objective:To observe the effects of biochanin A on learning and memory of ovariectomized rats and the histopathological changes in uterus and breast tissues,so as to look for a new drug instead of estradiol to prevent...
Objective:To observe the effects of estrogen/plant estrogen(Biochanin A,BCA)on learning and memory of ovariectomized rats,so as to explore the possible mechanisms of neuroprotective effect on endogenous growth hormone...
supported by National Natural Science Foundation of China(No.81274128);China National Funds for Distinguished Young Scientists(No.81125024);the Program of the State Key Development Program for Basic Research of China(No.2012CB723504)
Sex hormone estrogen is one of the most active intrinsic angiogenesis regulators; its therapeutic use has been limited due to its carcinogenic potential. Plant-derived phytoestrogens are attractive alternatives, but r...
Objective: The purpose of this review is to discuss some critical issues of isoflavones protective against the development of prostate cancer (PCa).Data Sources: Data cited in this review were obtained primarily f...
Type 2 diabetes(T2D)has become a major public health threat across the globe.It has been widely acknowledged that diet plays an important role in the development and management of T2D.Phytoestrogens are polyphenols th...
Supported by Grants from the Administration of Lanzhou Scientific Technology,No.2010-1-88;Gansu Natural Science Fund in China,No.1010RJZA111;Natural Science Foundation of China,No.21272103 and No.81360540
AIM: To investigate the effects and underlying mechanisms of resveratrol and genistein on contractile responses of rat gastrointestinal smooth muscle.