supported by the National Key Plan for Scientific Research and Development of China(2020YFA0509304);the Chinese Academy of Sciences(XDB39000000);the National Natural Sciences Foundation of China(82030034 and 32121002);CAMS Innovation Fund for Medical Sciences(IFMS)(2021-I2M-C&T-B012);the Fundamental Research Funds for the Central Universities(YD9110002027 and YD9110002033);Anhui Provincial Key R&D Programs(202304295107020056);the Guangzhou Key Research Program on Brain Science(202007030008)。
After a number of failed drug studies on Alzheimer’s disease(AD)over the past decade,clinical trials of AD started to show encouraging results and were approved or pending approval for clinical use.However,controvers...
National Natural Science Foundation of China(81401073 to XP);National Key R&D Program of China(2022YFC2503806)and NSFC(8237203)to YL;Province Natural Science Foundation of Shaanxi Province(2021SF-094 to XW).
Backgroud Epileptic spasms followed by a tonic component have been frequently observed in patients with late-onset spasms(LOS).However,there is a lack of comprehensive analysis and summary of clinical data related to ...
supported in part by the Natural Science Foundation of China(82001134,1949205,31730035,81721005);the Guangdong Provincial Key S&T Program(018B030336001);the Natural Science Foundation of Henan(242300421081).
Alzheimer’s disease(AD)is the most common neurodegenerative disorder,characterized pathologically by extracellular deposition ofβ-amyloid(Aβ)into senile plaques and intracellular accumulation of hyperphosphorylated...
supported by the National Natural Science Foundation of China(No.81573957,No.81874461 and No.82070307).
Atherosclerosis(AS)is characterized by impairment and apoptosis of endothelial cells,continuous systemic and focal inflammation and dysfunction of vascular smooth muscle cells,which is documented as the traditional ce...
Atherosclerosis(AS)is the main underlyingpathology of atherosclerotic cardiovascular disease(ASCVD),which is the leading cause of mortality inthe worldwide[1,2].Since the 19th century,Virchowhas already stated that AS...
The National Natural Science Foundation of China under contract Nos 41920104006;the Scientific Research Fund of Second Institute of Oceanography;Ministry of Natural Resources under contract Nos JZ2001,XRJH2410,and QNYC2102;the Oceanic Interdisciplinary Program of Shanghai Jiao Tong University under contract No.SL2021MS021;the Global Climate Changes and Air-sea Interaction Program under contract No.GASI-02-PAC-ST-Wwin;the Taishan Scholars Program under contract No.tsqn202306282。
The South China Sea(SCS)is a marginal sea connecting the Pacific and Indian oceans and has gained much attention in recent decades.The dynamics in the northeast SCS are considerably influenced by topography,monsoons,t...