POLYCOMB

作品数：61被引量：190H指数：7
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Polycomb and trithorax:Their yin-yang dynamics in plants
《Molecular Plant》2024年第6期845-847,共3页Fan Xu Daolei Zhang Liang Le Li Pu 
supported by funding from the Science and Technology Innovation 2030 Major Projects(2023ZD04076,2023ZD0407304,and 2022ZD0115703).
Polycomb(PcG)and trithorax(trxG)are two groups of conserved epigenetic complexes that maintain active and repressive states of target genes by altering their chromatin states to regulate plant development and stress r...
关键词：MAINTAIN COMPLEXES STATES 
Protein O-GlcNAcylation homeostasis regulates facultative heterochromatin to fine-tune sog-Dpp signaling during Drosophila early embryogenesis被引量：1
《Journal of Genetics and Genomics》2023年第12期948-959,共12页Yaowen Zhang Haibin Yu Dandan Wang Xiaoyun Lei Yang Meng Na Zhang Fang Chen Lu Lv Qian Pan Hongtao Qin Zhuohua Zhang Daan M.F.van Aalten Kai Yuan 
This project has been supported by the National Natural Science Foundation of China(grants 91853108,92153301,31771589,and 32170821 to K.Y,32101034 to F.C);Department of Science and Technology of Hunan Province(grants 2017RS3013,2017XK2011,2018DK2015,2019SK1012,and 2021JJ10054 to K.Y,and the innovative team program 2019RS1010);Central South University(2018CX032 to K.Y,2019zzts046 to Y.Z,2019zzts339 to X.L,2021zzts497 to H.Y,and the innovation-driven team project 2020CX016);D.M.F.v.A.is supported by Wellcome Trust Investigator Award(110061);a Novo Nordisk Foundation Laureate award(NNF21OC0065969).
Protein O-GlcNAcylation is a monosaccharide post-translational modification maintained by two evolutionarily conserved enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Mutations in human OGT have recently be...
关键词：Protein O-GlcNAcylation DROSOPHILA Early embryogenesis Polycomb repressive complex Facultative heterochromatin Neurodevelopment sog 
PCGF3分子功能及其在疾病中的作用
《基因组学与应用生物学》2023年第9期895-902,共8页尹琦 沈涛 
国家自然科学基金项目(82160384);云南省科技厅科技计划项目(2019FA030,202002AG070062);云南省卫生科技计划项目(L-2019003,2018NS260)共同资助。
多梳家族环指蛋白3(polycomb group ring finger 3,PCGF3)作为PCGF1-6的同源物,也是PCGF3-PRC1复合物的主要组成部分,该复合物具有特定的基因组定位和催化活性,可介导表观遗传组蛋白修饰,并在整个发育过程中维持包括Hox基因在内的许多...
关键词：多梳家族环指蛋白3 PCGF3-PRC1 Polycomb家族 疾病 
Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia被引量：1
《Acta Biochimica et Biophysica Sinica》2023年第2期202-214,共13页Lin Xie Ning Ding Siqi Sheng Honghong Zhang He Yin Lina Gao Hui Zhang Shengchao Ma Anning Yang Guizhong Li Yun Jiao Qing Shi Yideng Jiang Huiping Zhang 
This work was supported by the grants from the National Natural Science Foundation of China(Nos.U21A20343,82171682,and 82270492);the Natural Science Foundation of Ningxia Hui Autonomous Region(No.2020AAC02038);the Key Research and Development Projects in Ningxia Hui Autonomous Region(Nos.2019BFG02004,2021BEG02028,2020BEG03005,2020BFH02003,and 2022BEG02054);the Basic Scientific Research Operating Expenses from the public welfare research institutes at the central level of the Chinese Academy of Medical Sciences(No.2019PT330002).
Accumulating evidence has shown that the apoptosis of trophoblast cells plays an important role in the pathogenesis of preeclampsia,and an intricate interplay between DNA methylation and polycomb group(PcG)proteinmedi...
关键词：PREECLAMPSIA nervous system polycomb 1 DNA methyltransferase 3a HOXA11 apoptosis 
Rif1 interacts with non-canonical polycomb repressive complex PRC1.6 to regulate mouse embryonic stem cells fate potential被引量：2
《Cell Regeneration》2022年第1期246-266,共21页Lu Li Pishun Li Jiale Chen Li Li Yunfan Shen Yangzixuan Zhu Jiayi Liu Lu Lv Song Mao Fang Chen Guang Hu Kai Yuan 
This project has been supported by the National Natural Science Foundation of China(32170821,31771589 to K.Y);Ministry of Science and Technology of the People’s Republic of China(2021YFC2701202);Department of Science&Technology of Hunan Province(2021JJ10054,2019SK1012,2018DK2015,2017RS3013,2017XK2011 to K.Y,2019JJ40478 to P.L,and the innovative team program 2019RS1010);Central South University(2018CX032 to K.Y,and the innovation-driven team project 2020CX016)。
Mouse embryonic stem cells(mESCs)cycle in and out of a transient 2-cell(2C)-like totipotent state,driven by a com-plex genetic circuit involves both the coding and repetitive sections of the genome.While a vast array ...
关键词：2C-like TOTIPOTENCY MERVL Rif1 PRC1.6 
H3K27me3 shapes DNA methylome by inhibiting UHRF1-mediated H3 ubiquitination被引量：2
《Science China(Life Sciences)》2022年第9期1685-1700,共16页Honglian Zhang Ying Liu Yali Xie Yunji Zhu Jingwen Liu Falong Lu 
supported by the National Key Research and Development Program of China (2018YFA0107001, 2018YFC1004000);the CAS Project for Young Scientists in Basic Research (YSBR-012);the National Natural Science Foundation of China (32070607)。
DNA methylation and histone lysine tri-methylation at H3K27(H3K27me3)are two chromatin modifications for transcriptional gene silencing,which play important roles in diverse biological processes,including cell fate de...
关键词：DNA methylation H3K27me3 UHRF1 POLYCOMB H3 ubiquitination 
Polycomb Repressive Complex 2-Mediated H3K27 Trimethylation Is Required for Pathogenicity in Magnaporthe oryzae被引量：2
《Rice science》2022年第4期363-374,共12页WU Zhongling QIU Jiehua SHI Huanbin LIN Chuyu YUE Jiangnan LIU Zhiquan XIE Wei Naweed INAQVI KOU Yanjun TAO Zeng 
the National Natural Science Foundation of China(Grant Nos.32170192 and 32000103);Zhejiang Science and Technology Major Program on Agricultural New Variety Breeding(Grant No.2021C02064);Key Research and Development Project of China National Rice Research Institute(Grant No.CNRRI-2020-04);the Chinese Academy of Agricultural Sciences under the‘Elite Youth’Program and the Agricultural Sciences and Technologies Innovation Program.
Polycomb repressive complex 2(PRC2)contributes to catalyze the methylation of histone H3 at lysine 27 and plays vital roles in transcriptional silencing and growth development in various organisms.In Magnaporthe oryza...
关键词：rice blast H3K27me3 transcriptional regulation PATHOGENICITY Polycomb repressive complex 2 
Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants被引量：2
《Plant Communications》2022年第1期135-151,共17页Fernando Baile Angeles Gomez-Zambrano Myriam Calonje 
This work was supported by a PID2019-106664GB-I00 grant from the Spanish Ministry of Science and Innovation.
The evolutionary conserved Polycomb Group(PcG)repressive system comprises two central protein complexes,PcG repressive complex 1(PRC1)and PRC2.These complexes,through the incorporation of histone modifications on chro...
关键词：Polycomb Group PRC1 PRC2 histone modifications gene repression chromatin organization 
Genomewide decoupling of H2AK119ub1 and H3K27me3 in early mouse development被引量：2
《Science Bulletin》2021年第24期2489-2497,M0004,共10页Yezhang Zhu Jiali Yu Yan Rong Yun-Wen Wu Yang Li Lejiao Zhang Yinghao Pan Heng-Yu Fan Li Shen 
supported by the National Natural Science Foundation of China(32022023 and 31871478);the National Key Research and Development Programs of China(2017YFC1001500);Zhejiang Provincial Natural Science Foundation of China(LR18C060001)。
Polycomb group(Pc G)proteins are crucial chromatin regulators during development.H2 AK119 ub1(H2 Aub)and H3 K27 me3 are catalyzed by Polycomb-repressive complex 1 and 2(PRC1/2)respectively,and they largely overlap in ...
关键词：POLYCOMB H2AK119ub1 H3K27me3 Preimplantation development Non-canonical imprinting 
Comprehensive genomic analysis and expression profiling of cysteine-rich polycomb-like transcription factor gene family in tea tree被引量：2
《Horticultural Plant Journal》2021年第5期469-478,共10页Hong Nan Yanglei Lin Xinghua Wang Lizhi Gao 
supported by Yunnan Innovation Team Project.
Cysteine-rich polycomb-like(CPP)is a small gene family in plants,which plays key role in plant development and stress response.Although CPP transcription factors have been characterized in several other plant species,...
关键词：Camellia sinensis CPP transcription factor Genome-wide analysis Gene expression profiling 
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