supported fnancially by the Nanseishoto Project of WWFJ,Pro Natura Foundation Japan’s 31st Pro Natura Fund;the Project for Biodiversity Conservation Promotion of the Japan Ministry of the Environment.
There are many short-lived animals,but those displaying a lifecycle with more than one generation per year(multivoltine lifecycle)are rare amongterrestrial vertebrates.The multivoltine lifecycle requires rapid growth ...
BACKGROUND At present,the clinical mechanisms underlying precocious puberty remain unclear,making effective intervention for children experiencing this condition and rapidly progressive puberty essential.AIM To explor...
Supported by National Natural Science Foundation-funded Project:Study on the Experimental Animal Model of Precocious Puberty with Syndrome of Yin Deficiency and Fire Hyperactivity by Changing the Cycle of Light Exposure(No.81373692);The Constructive Project of Flagship Hospital of Integrated TCM with Western Medicine in Children’s Hospital of Fudan University[No.ZY(2021-2023)-0205-03];the Network Coverage of Coordinated Medical Practice Combined TCM with Western Medicine in Fudan Pediatric Medical Partnerships Union[ZY(2021-2023)-0206-06]。
OBJECTIVE:To elucidate the mechanism of the nourishing Yin and purging fire Chinese herbal mixture(NYPF)in delaying light-induced premature puberty in rats.METHODS:Twenty-one days old female SpragueDawley rats were ra...
the National Natural Science Foundation of China(32071025,31921002,and 31730108);the Beijing Municipal Science&Technology Commission(Z181100001518001);the Interdisciplinary Research Fund of Beijing Normal University;the Strategic Priority Research Program and Innovation Program of the Chinese Academy of Sciences(XDB32020100)。
Brain-specific loss of a microtubule-binding protein collapsin response mediator protein-2(CRMP2)in the mouse recapitulates many schizophrenia-like behaviors of human patients,possibly resulting from associated develo...
This work was supported by the China Ministry of Agriculture Fujian Honeybee Biology Observation Station grant(2015-350426-G1203-053);National Natural Science Foundation of China(31401737,31171874 and 31321004);Beijing talents fund(2015000021223ZK29);Beijing Nova Program(Z1511000003150118);US Department of Agriculture National Institute of Food and Agriculture(hatch grant ARZT-1360890-H31-164 and multi state grant ARZT-1370400-R31-168);State Key Laboratory for Biology and of Plant Diseases and Insects(SKLOF201402 and SKLOF201504).
Workers of Apis cerana cerana undergo an in-hive nursing to outdoor foraging transition,but the genes underlying this age-related transition remain largely unknown.Here,we sequenced the head transcriptomes of its 7-da...
the Strategic PriorityResearch Program of the Chinese Academy of Sciences(XDB19000000 and XDA12040323);the National Natural ScienceFoundation of China(91853128,31470770 and 81525019to R.H.;81773023 to S.G.);the model animal project of ShanghaiScience and Technology Commission(19140903500);theMinistry of Science and Technology of China(2019YFA082103and 2018ZX10101004);China Postdoctoral Science Foundation(2018M642109);the National Natural Science Foundation of China(31900804)to C.L.;supported by the Shanghai Municipal Science andTechnology Major Project(2017SHZDZX01).
Central precocious puberty(CPP)refers to a human syndrome of early puberty initiation with characteristic increase in hypothalamic production and release of gonadotropin-releasing hormone(GnRH).Previously,loss-of-func...
Introduction:Incomplete pubertal development is a common phenomenon found in patients with Klinefelter syndrome (KFS).KFS combined with central precocious puberty (CPP) rarely occurs.We herein report a rare case of KF...
Background Internationally adopted children (IAC) can present growth impairment at arrival,which usually recovers over time.Moreover,a major prevalence of precocious puberty has been reported in this group.Methods All...
Central precocious puberty (CPP)is one of the most common and complex problems in clinical pediatric endocrinology practice. Currently,CPP is believed to result from complex interactions between genetic,endocrinal,nut...
Supported by the Shanghai Integrated Chinese and Western Medicine Key Diseases Construction Projects(No.zxbz2012-14);a Medical Guidance Item of the Shanghai Science and Technology Commission(No.12401906900);by the Chinese Medicine Prescription Project of the Shanghai Shenkang Hospital Development Center(No.SHDC12012414);by the Development Project of the Shanghai Peak
OBJECTIVE: To evaluate the effect of ZiYin Xiehuo granules(ZYXH) and Zishen Qinggan granules(ZSQG) on partial precocious puberty(PPP).METHODS: This was a multicenter, randomized, single-blind, positive-controlled tria...