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作品数：2328被引量：5787H指数：25
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Biomarkers in aortic dissection:Diagnostic and prognostic value from clinical research被引量：2
《Chinese Medical Journal》2024年第3期257-269,共13页Yufei Zhao Weiguo Fu Lixin Wang 
supported by grants from the National Natural Science Foundation of China(No.81970412);the Science and Technology Innovation Plan of the Shanghai Science and Technology Commission(No.18441902400)
Aortic dissection is a life-threatening condition for which diagnosis mainly relies on imaging examinations,while reliable biomarkers to detect or monitor are still under investigation.Recent advances in technologies ...
关键词：Aortic dissection BIOMARKER PROTEIN Cell-free DNA MIRNA INFLAMMATION Lipid-metabolism 
Evaluation of the immunogenicity and protective efficacy of a Chlamydia muridarum protein OmcB and its C segment in BALB/c mice
《Chinese Medical Journal》2023年第21期2638-2640,共3页Han Deng Tudi Chen Pinglu Li Wanxing Zhao Congzhong Zhu Yuyang Zhang Huiping Wang Shuping Hou 
supported by grants from the National Natural Science Foundation(No.31770194);Tianjin Key Medical Discipline(specialty)Construction Project(No.TJYXZDXK-057B);Zhejiang Provincial Natural Science Foundation(No.LY18C01003).
To the Editor:Chlamydia trachomatis(Ct)is an obligate intracellular bacterium that can infect the human urogenital system and cause cervicitis,salpingitis,and pelvic inflammatory diseases.Ct infections can be easily t...
关键词：CHLAMYDIA protective DIAGNOSIS 
Role of steroid receptor-associated and regulated protein in tumor progression and progesterone receptor signaling in endometrial cancer
《Chinese Medical Journal》2023年第21期2576-2586,共11页Jie Liu Zhiqi Wang Jingyi Zhou Jiaqi Wang Xiangjun He Jianliu Wang 
supported by grants from the National Key Technology R&D Program of China(Nos.2019YFC1005200 and 2019YFC1005201).
Background:Steroid receptor-associated and regulated protein(SRARP)suppresses tumor progression and modulates steroid receptor signaling by interacting with estrogen receptors and androgen receptors in breast cancer.I...
关键词：SRARP Progesterone receptor Epithelial-mesenchymal transition COREGULATOR Tumor suppressor Endometrial cancer 
USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/β-catenin signaling pathway被引量：1
《Chinese Medical Journal》2023年第18期2229-2242,共14页Yinghui Liu Jingjing Ma Shimin Lu Pengzhan He Weiguo Dong 
National Natural Science Foundation of China(No.81870392)
Background:Hepatocellular carcinoma(HCC)is one of the most common malignant tumors in the world.The ubiquitin-specific peptidase 25(USP25)protein has been reported to participate in the development of several cancers....
关键词：Hepatocellular carcinomas USP25 protein human TRIM21 protein human Wnt/β-catenin signaling pathway Epithelial-mesenchymal transition 
Overexpression of ASPH protein predicts poor outcomes in retroperitoneal liposarcoma patients
《Chinese Medical Journal》2023年第17期2113-2115,共3页Mengmeng Xiao Xiaobing Chen Weida Chen Lihua Wang Xiaosong Rao Chenghua Luo 
Peking University International Hospital Research Grant(No.YN2019QN11);Beijing Science and Technology Commission"Applied research on clinical characteristics of the capital city"(No.Z171100001017095)
To the Editor:Liposarcoma is a common subtype of retroperitoneal sarcoma.Due to the complicated anatomical heterogeneity of retroperitoneal liposarcoma(RPLS),it compresses and invades adjacent important organs,and mas...
关键词：SARCOMA PATIENTS SURGERY 
H19 recruited N^(6)-methyladenosine(m^(6)A)reader YTHDF1 to promote SCARB1 translation and facilitate angiogenesis in gastric cancer被引量：3
《Chinese Medical Journal》2023年第14期1719-1731,共13页Rumeng Bai Miaomiao Sun Yuanyuan Chen Shuaishuai Zhuo Guoxin Song Tianjun Wang Zhihong Zhang 
Background:Angiogenesis is described as a complex process in which new microvessels sprout from endothelial cells of existing vasculature.This study aimed to determine whether long non-coding RNA(lncRNA)H19 induced th...
关键词：Gastric cancer H19 long non-coding RNA ANGIOGENESIS YTHDF1 protein human SCARB1 protein human 6-methyladenine 
Reverse effect of Semaphorin-3F on rituximab resistance in diffuse large B-cell lymphoma via the Hippo pathway
《Chinese Medical Journal》2023年第12期1448-1458,共11页Qiong Li Naya Ma Xinlei Li Chao Yang Wei Zhang Jingkang Xiong Lidan Zhu Jiali Li Qin Wen Lei Gao Cheng Yang Lingyi Rao Li Gao Xi Zhang Jun Rao 
National Natural Science Fund(No.82070208);National Natural Science Foundation of Chongqing(cstc2020jcyjmsxmX0433);Major program of Chongqing Health Commission and Science and Technology Bureau Joint project(2022DBXM003);Chongqing Science and Health Joint medical research project(2023QNXM047);Military clinical medical innovation project of Xinqiao hospital(2021JSLC0003);Science and technology innovation promotion project of AMU(2019XLC3020);Translational Research Grant of NCRCH(2020ZKZC02 and 2021WWB05)
Background:Exploring the underlying mechanism of rituximab resistance is critical to improve the outcomes of patients with diffuse large B-cell lymphoma(DLBCL).Here,we tried to identify the effects of the axon guidanc...
关键词：Lymphoma large B-cell diffuse Rituximab resistance APOPTOSIS WW domain-containing transcription regulator protein 1 
Leucine-rich repeats containing 4 protein(LRRC4)in memory,psychoneurosis,and glioblastoma
《Chinese Medical Journal》2023年第1期4-12,共9页Kun Deng Minghua Wu 
National Natural Science Foundation of China(No.82073096);Hunan Provincial Natural Science Foundation of China(No.2022JJ40578)
Leucine-rich repeats containing 4(LRRC4,also named netrin-G ligand 2[NGL-2])is a member of the NetrinGs ligands(NGLs)family.As a gene with relatively high and specific expression in brain,it is a member of the leucine...
关键词：Netrin G Excitatory synapses Long-term potentiation AUTISM Multiple sclerosis GLIOBLASTOMA 
Association between follistatin-related protein 1 and the functional status of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis
《Chinese Medical Journal》2021年第10期1168-1174,共7页Taejun Yoon Sung Soo Ahn Jung Yoon Pyo Jason Jungsik Song Yong-Beom Park Sang-Won Lee 
supported by a faculty research grant from the Yonsei University College of Medicine(No.6-2019-0184);a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute,funded by the Ministry of Health and Welfare,Republic of Korea(No.HI14C1324)。
Background:Follistatin-like 1(FSTL1)plays both pro-inflammatory and anti-inflammatory roles in the inflammatory processes.We investigated whether serum FSTL1 could predict the current anti-neutrophil cytoplasmic antib...
关键词：Anti-neutrophil cytoplasmic antibody Follistatin-like 1 Functional status VASCULITIS 
Monocyte chemotactic protein-inducing protein 1 negatively regulating asthmatic airway inflammation and mucus hypersecretion involvingγ-aminobutyric acid type A receptor signaling pathway in vivo and in vitro被引量：3
《Chinese Medical Journal》2021年第1期88-97,共10页Guang-Ming Dai Jia-Jia Wang Zhi-Hong Chen Ya-Juan Ran Huo-Jin Deng Ruo-Lin Mao Tao Zhu 
supported by grants from the National Natural Science Foundation of China for Young Scholar(No.81801484);China Postdoctoral Science Foundation(No.2014M552369);Natural Science Foundation of Guangdong Province(No.2017A030310286);Scientific Research Project of Guangzhou(No.201707010282)。
Background:Mounting evidence,consistent with our previous study,showed thatγ-aminobutyric acid type A receptor(GABAAR)played an indispensable role in airway inflammation and mucus hypersecretion in asthma.Monocyte ch...
关键词：Airway inflammation Airway mucus hypersecretion Gamma-aminobutyric acid type A receptor GABAAR IL-13 MCPIP1 Monocyte chemotactic protein-inducing protein 1 OVALBUMIN 
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