Dual-specificity tyrosine phosphorylation-regulated kinase 1B(DYRK1B),also known as minibrain-related kinase(MIRK)is one of the best functionally studied members of the DYRK kinase family.DYRKs comprise a family of pr...
Quiescent state has been observed in stem cells(SCs),including in adult SCs and in cancer SCs(CSCs).Quiescent status of SCs contributes to SC self-renewal and conduces to averting SC death from harsh external stimuli....
The discovery of cancer stem cells caused a paradigm shift in the concepts of origin and development of colorectal cancer. Several unresolved questions remain in this field though. Are colorectal cancer stem cells the...
SA:Sapienza University 2012(#C26A125ENW)and PRIN 2012(#2012N8YJC3);NM:Sapienza University"Avvio alla ricerca"2014;VM:EU Marie Curie"Muscle repair-Mdx",Italian Ministry of Instruction,University and Research FIRB project and Italian Ministry of Health"Ricerca finalizzata"grants
Epigenetics finely tunes gene expression at a functionallevel without modifying the DNA sequence, thereby contributing to the complexity of genomic regulation. Satellite cells(SCs) are adult muscle stem cells that are...
Supported by A grant from the National Science Council,Taiwan
Scientific evidence suggests that stem cells possess the anti-aging ability to self-renew and maintain differentiation potentials, and quiescent state. The objective of this review is to discuss the microenvironment w...