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作品数:722被引量:1250H指数:13
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相关机构:北京师范大学陕西中医药大学附属医院东南大学新疆医科大学第一附属医院更多>>
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Mogroside V protects against acetaminophen-induced liver injury by reducing reactive oxygen species and c-jun-N-terminal kinase activation in mice
《World Journal of Hepatology》2025年第3期170-179,共10页Jia-Lin Shi Tian Sun Qing Li Chun-Mei Li Jun-Fei Jin Chong Zhang 
Supported by Guangxi Natural Science Foundation of China,No.2024GXNSFAA010040;Special Fund of the Central Government Guiding Local Scientific and Technological Development by Guangxi Science and Technology Department,No.GuikeZY21195024;National Natural Science Foundation of China,No.82260499 and No.82460463.
BACKGROUND High levels of acetaminophen(APAP)consumption can result in significant liver toxicity.Mogroside V(MV)is a bioactive,plant-derived triterpenoid known for its various pharmacological activities.However,the i...
关键词:ACETAMINOPHEN Mogroside V Reactive oxygen species Liver injury C-jun-N-terminal kinase 
Hyperthermia combined with opioid therapy:Enhancing cancer pain management and reducing surgical stress in gastrointestinal cancer patients
《World Journal of Gastrointestinal Surgery》2025年第3期14-20,共7页Yue Wang Xin Xun Wen-Yu Luan Zheng Zhang Zhen-Xi Xu Si-Xiang Lin Yan-Dong Miao 
Supported by the Shandong Province Medical and Health Science and Technology Development Plan Project,No.202203030713;Science and Technology Program of Yantai Affiliated Hospital of Binzhou Medical University,No.YTFY2022KYQD06.
In this article,we evaluate the findings of the study by Qian et al,which explores the efficacy of combining hyperthermia with opioid therapy for enhanced cancer pain management in patients with middle and late-stage ...
关键词:Gastrointestinal cancer HYPERTHERMIA Opioid therapy Cancer pain management Surgical stress reduction Enhanced recovery Adverse reactions Pain control 
Effect of esketamine on reducing postpartum pain and depression
《World Journal of Clinical Cases》2025年第7期17-20,共4页Brandon Lucke-Wold Armin Karamian 
In this editorial,we comment on a recent article by Chen et al,that addressed the effect of intraoperative injection of esketamine on postoperative analgesia and postoperative rehabilitation after cesarean section.Poo...
关键词:Cesarean section Postpartum pain Postpartum depression Postoperative analgesia Esketamine 
Reducing invasiveness in liver surgery-where is the limit?
《World Journal of Gastrointestinal Surgery》2025年第2期316-319,共4页Ivan Romic Ivan Separovic Dora Grgic Igor Petrovic Josip Mavrek Hrvoje Silovski 
In this article,we comment on the article by Wang et al published in the recent issue of the World Journal of Gastroenterology Surgery.Most prominent advancements in liver surgery in the last two decades are related t...
关键词:Liver resection LAPAROSCOPY Glissonean approach SEGMENTECTOMY 
DNA2 knockout aggravates cerebral ischemia/reperfusion injury by reducing postsynaptic Homer1a
《Zoological Research》2025年第1期87-102,共16页Ting Ma Yu-Meng Li Peng-Yu Ren Shi-Quan Wang Xiang-Long Liu Wen-Bo Lv Wu-Gang Hou Wen-Qiang Zuo Wei-Qiang Lin Jian Sima An-Qi Geng 
supported by the National Natural Science Foundation of China (32070979);Shenzhen Science and Technology Program (JCYJ20220530161604009,JCYJ20240813150734043);Key Research and Development Program of Shaanxi (2024SF,YBXM,050);Fundamental Research Funds for the Central Universities (31020190QD004,3102019YX01001);Double First-Class Project of China Pharmaceutical University (CPUQNJC22_02);Global Pharmaceutical Development Alliance Plan of China Pharmaceutical University (1302090024-05)。
DNA2,a multifunctional enzyme with structure-specific nuclease,5'-to-3'helicase,and DNA-dependent ATPase activities,plays a pivotal role in the cellular response to DNA damage.However,its involvement in cerebral ische...
关键词:DNA2 Homer1a Cerebral I/R OGD/R Neuronal apoptosis 
Curcumin attenuates ochratoxin A and hypoxia co‑induced liver injury in grass carp(Ctenopharyngodon idella)by dual targeting endoplasmic reticulum stress and apoptosis via reducing ROS content
《Journal of Animal Science and Biotechnology》2025年第1期408-423,共16页Liangqin Wu Piao Zhao Pei Wu Weidan Jiang Yang Liu Hongmei Ren Xiaowan Jin Xiaoqiu Zhou Lin Feng 
This research was financially supported by the earmarked fund for CARS(CARS-45);National Natural Science Foundation of China(32273144,32072985);National Key R&D Program of China(2019YFD0900200).
Background Ochratoxin A(OTA)is a toxin widely found in aquafeed ingredients,and hypoxia is a common prob-lem in fish farming.In practice,aquatic animals tend to be more sensitive to hypoxia while feeds are contaminate...
关键词:APOPTOSIS CURCUMIN Endoplasmic reticulum stress Grass carp HYPOXIA Ochratoxin A Oxidative damage 
Reducing the measurement errors in nonadiabatic holonomic quantum computers
《Science China(Physics,Mechanics & Astronomy)》2025年第1期60-66,共7页Guo-Fu Xu 
supported by the National Natural Science Foundation of China(Grant No.12174224)。
Nonadiabatic holonomic quantum computers serve as the physical platform for nonadiabatic holonomic quantum computation.As quantum computation has entered the noisy intermediate-scale era,building accurate intermediate...
关键词:quantum holonomy quantum computation measurement errors 
Biochar as a Climate-Smart Agricultural Practice: Reducing Greenhouse Gas Emissions and Promoting Sustainable Farming
《Phyton-International Journal of Experimental Botany》2025年第1期65-99,共35页Muhammad Nazim Abdul Ghafoor Abida Hussain Mehwish Tabassum Aamir Nawaz Muhammad Ahmad Murad Muhammad Muqarrab Ali 
Deanship of Scientific Research(DSR)at King Faisal University,Saudi Arabia,under project number KFU241939.
In recent years, the world has faced rising global temperatures, accumulative pollution, and energy crises, stimulating scientists worldwide to strive for eco-friendly and cost-effective solutions. Biochar has materia...
关键词:AGRO-ECOLOGY BIOCHAR carbon storage greenhouse gas reduction sustainable agriculture 
Enhancing the radiosensitivity of colorectal cancer cells by reducing spermine synthase through promoting autophagy and DNA damage
《World Journal of Gastrointestinal Oncology》2024年第12期4716-4727,共12页Yu-Bin Guo Yue-Ming Wu Zhi-Zhao Lin 
Supported by National Natural Science Foundation of China,No.82102996;Guangdong Provincial Natural Science Foundation,No.2022A1515010517;Guangzhou Science and Technology Plan Project,No.202201011016;President Foundation of Nanfang Hospital,Southern Medical University,No.2020C038.
BACKGROUND Colorectal cancer(CRC),the third most common cancer worldwide,has increasingly detrimental effects on human health.Radiotherapy resistance diminishes treatment efficacy.Studies suggest that spermine synthas...
关键词:Spermine synthase Colorectal cancer RADIOSENSITIVITY AUTOPHAGY DNA damage 
Reducing off-target effects of DdCBEs by reversing amino acid charge near DNA interaction sites
《Cell Research》2024年第12期877-881,共5页Long Xie Yaqi Cao Di Li Mengxue Ma Danrong Jiao Hu Feng Zhenrui Zuo Erwei Zuo 
Dear Editor,DddA_(tox)-derived cytosine base editors(DdCBEs)can mediate precise,CRISPR-independent editing of mitochondrial DNA(mtDNA),but were recently shown to potentially introduce extensive and non-trivial off-tar...
关键词:TRIVIAL utilizing PRECISE 
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